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Our top choices for Southeast Missouri luxury hotels

Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely
2.0 star property
Pevely
5.6 out of 10, (837 reviews)
"did not use pool need lids for coffee"
United States
Carol
The price is ₹7,489
₹8,602 total
includes taxes & fees
16 Apr - 17 Apr
Super 8 by Wyndham Pevely

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,001 reviews)
"This was our third stay at this Motel 6. It’s a great hotel with friendly staff, clean rooms and good location. Pets stay free!"
United States
Amy
The price is ₹6,472
₹6,827 total
includes taxes & fees
18 Mar - 19 Mar
Motel 6 Poplar Bluff, MO

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,005 reviews)
"Great clean and quiet room "
United States
Susan
The price is ₹6,287
₹7,166 total
includes taxes & fees
19 Mar - 20 Mar
Days Inn and Suites by Wyndham Sikeston

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (922 reviews)
"Parking was okay. It seems alot of construction workers stay here."
United States
Tracy
The price is ₹6,583
₹7,692 total
includes taxes & fees
22 Mar - 23 Mar
Comfort Inn Festus - St Louis South

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (636 reviews)
"The room was clean. Staff was pleasant and helpful. Will stay there again, when in Poplar Bluff area."
United States
James
The price is ₹5,108
₹5,771 total
includes taxes & fees
12 Apr - 13 Apr
Super 8 by Wyndham Poplar Bluff Missouri

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
Festus
6.8 out of 10, (942 reviews)
"Room was good and staff was helpful and friendly"
United States
Michael
The price is ₹7,489
₹8,564 total
includes taxes & fees
19 Mar - 20 Mar
Baymont by Wyndham Festus

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (710 reviews)
"Room was clean. Staff was friendly. Hotel itself is due for a renovation. You get what you pay for. 2.5 out of 5 for this place "
United States
Robin
The price is ₹6,158
₹6,947 total
includes taxes & fees
23 Mar - 24 Mar
Quality Inn Cape Girardeau North

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,005 reviews)
"Very nice for overnight stay"
United States
Scott
The price is ₹8,690
₹9,992 total
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"The room was great and the staff was friendly as always. "
United States
LuAnne
The price is ₹8,320
₹9,387 total
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Southeast Missouri

Southeast Missouriand its attractions for luxury travelers

Southeast Missouri boasts a compelling blend of natural beauty and cultural richness, perfect for the discerning traveller seeking luxury. Begin your journey in Cape Girardeau, where the historic Riverfront adds charm to your stay; indulge in a gourmet meal at a riverside restaurant followed by a leisurely stroll along the Mississippi River. For a touch of adventure, head to the stunning trails of the Ozark National Scenic Riverways, where you can explore crystal-clear springs and enjoy a private guided canoe tour, immersing yourself in Missouri's breathtaking landscapes. The historic town of Ste. Genevieve, rich in French historic architecture, offers boutique shopping and exquisite dining experiences that cater to refined tastes. The region’s acclaimed wineries, such as the nearby Chaumette Vineyards, provide exclusive tastings and vineyard tours, perfect for an afternoon of indulgence. For a luxurious stay, consider the upscale options in Cape Girardeau, where hotels offer stunning views of the river along with top amenities and personalised services, ensuring that you feel pampered throughout your visit.

Top Southeast Missouri Hotel Reviews