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Our top choices for Southeast Missouri hotels with suites

Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,009 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
United States
Jamie
The price is ₹9,083
₹9,603 total
includes taxes & fees
2 Aug - 3 Aug
Drury Inn & Suites Jackson MO
View from property

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (86 reviews)
"I really enjoyed my time at the stay !"
United States
Ronrecus
The price is ₹8,893
₹13,685 total
includes taxes & fees
13 Aug - 14 Aug
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Desk, iron/ironing board, free cots/infant beds, rollaway beds

Comfort Inn Willow Springs US 60 and US 63

Comfort Inn Willow Springs US 60 and US 63
2.5 star property
Willow Springs
9.2 out of 10, Wonderful, (598 reviews)
"Always clean room & quality service"
United States
Dennis
The price is ₹10,485
₹11,288 total
includes taxes & fees
9 Aug - 10 Aug
Comfort Inn Willow Springs US 60 and US 63
Breakfast, dinner and brunch served

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (338 reviews)
"Great hotel and nice staff!"
United States
Michelle
The price is ₹9,601
₹10,655 total
includes taxes & fees
16 Jul - 17 Jul
The Principal Hotel
Indoor pool, outdoor pool

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,017 reviews)
"Great place!"
United States
Jennifer
The price is ₹10,613
₹12,203 total
includes taxes & fees
26 Jul - 27 Jul
Drury Inn & Suites Sikeston, MO
Exterior

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (420 reviews)
"Staff was excellent. It was fine for what it was — a cheap place near the highway"
United States
Emily
The price is ₹6,812
₹7,560 total
includes taxes & fees
19 Jul - 20 Jul
The Riverstone Hotel Charleston-Sikeston
Exterior

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (606 reviews)
"Breakfast was good nice beds very nice stay"
United States
scott
The price is ₹8,478
₹9,705 total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites Perryville by IHG
Lobby

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,006 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
United States
Stephanie
The price is ₹8,988
₹10,154 total
includes taxes & fees
2 Aug - 3 Aug
Drury Inn & Suites Poplar Bluff
Lobby

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
3.0 star property
Hayti
9.4 out of 10, Exceptional, (1,009 reviews)
"Excellent friendly stag and great amenities"
United States
Steven
The price is ₹10,135
₹11,552 total
includes taxes & fees
31 Jul - 1 Aug
Drury Inn & Suites Hayti Caruthersville
Outdoor dining

Perryville RV Resort

Perryville RV Resort
2.0 star property
Perryville
10.0 out of 10, Exceptional, (1 review)
"We had a amazing time it was our 4 yr anniversary"
United States
Von
The price is ₹7,055
₹8,076 total
includes taxes & fees
20 Jul - 21 Jul
Perryville RV Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Convince to interstate"
Kendall 1-night trip
Posted 1 day ago
Drury Inn & Suites Hayti Caruthersville

Frequently asked questions

How much do hotels with suites in Southeast Missouri cost?
You'll pay between ₹7,560 and ₹13,685 per night for hotels with suites in Southeast Missouri. Whatever your plans or budget, Expedia will help you find a home away from home with the spaciousness you're after. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with suites in Southeast Missouri?
Southeast Missouri offers multiple hotels with suites, with a total average guest review rating of 9.3. Planning a trip to Cape Girardeau? Put your bags down at Hampton Inn Cape Girardeau I 55 East, a popular 2.5-star city base with a dining venue and a terrace. Another recommended choice with suite rooms is Drury Plaza Hotel Cape Girardeau Conference Centre. It has a 3-star rating and amenities including a swimming pool and complimentary breakfast.
How many hotels with suites are there in Southeast Missouri?
Southeast Missouri has 9 hotels with suites to choose from. Enter your destination and travel dates and get a start on planning your perfect getaway today.
What are the best cheap hotels with suites in Southeast Missouri?
In Southeast Missouri, hotels with suites start from just ₹7,560 per night, which means you'll have plenty of cash left over for exploring. If Cape Girardeau is in your travel plans, check in at Hampton Inn Cape Girardeau I 55 East. As well as suite rooms, it comes with pool sun loungers and a terrace. Expedia also has inexpensive hotels with suites in Sikeston. Settle in at Pear Tree Inn Sikeston and take advantage of handy amenities including a swimming pool and front desk services. Discover Southeast Missouri on a shoestring by filling your sightseeing itinerary with fabulous free attractions. Hunter Valley Winery in Cape Girardeau is popular. If you're spending some time in Sikeston, you won't have to spend a cent when you visit Sikeston Depot Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels with suites in Southeast Missouri?
You'll find superb family-friendly hotels that offer this accommodation type in Southeast Missouri. If you're making tracks for Cape Girardeau, make a booking at Drury Plaza Hotel Cape Girardeau Conference Centre. With suites and useful amenities such as complimentary breakfast and housekeeping services, your entire crew will enjoy chilling out at this 3-star property. Drury Inn & Suites Cape Girardeau is also a top pick for families in Cape Girardeau. This 3-star option comes with complimentary breakfast, a laundry service and comfy suite rooms. Cape Girardeau offers plenty of family-friendly attractions when you're ready to head out and explore. Cape Splash Family Aquatic Centre and Lazy L Safari Park promise fun for the entire crew.
How can I find cheap hotels with suites in Southeast Missouri?
Expedia's filters will help you find a cheap hotel with suites in Southeast Missouri. First, set your nightly budget. Next, choose your preferred hotel star rating — the lower the rating, the more affordable the stay. You can also search for hotels in less popular neighbourhoods or ones that are located away from the centre. Like another tip? Join One Key™, our free travel rewards programme, to access our best prices.
Why book your hotel with suites in Southeast Missouri with Expedia?
Booking a hotel with suites in Southeast Missouri is as simple as deciding on your travel dates and selecting an option that suits you best. Seeking something low cost or luxurious, or a property that also has a particular amenity like a pool or spa? Expedia's filters make it a breeze to narrow down your search results and find your perfect match.
What is there to do in Southeast Missouri near my hotel with suites?
No matter your interests, there are so many things to put on your to-do list in Southeast Missouri. If you're holidaying in Cape Girardeau, check out Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site. Basing yourself in Ste Genevieve? Sainte Genevieve Winery, Bolduc House Museum and Felix Valle House State Historic Site are among the best sights in this city.

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