TOP Luxury Hotels in South San Francisco, CA for 2026

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Our top choices for South San Francisco luxury hotels

An outdoor dining area with tables and chairs, surrounded by glass walls and trees.

1. AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Oyster Point

₹17,101 total

includes taxes & fees

28 Nov - 29 Nov

A modern bar area with a long counter, bar stools, and a large window overlooking a body of water.

2. San Francisco Airport Marriott Waterfront

Ingold - Milldale

Waterfront elegance meets luxury and bay views at this San Francisco hotel with 24-hour airport shuttles.

₹15,187 total

includes taxes & fees

27 Nov - 28 Nov

A hotel with a modern facade, multiple floors, and a well-lit entrance.

3. The Westin San Francisco Airport

Ingold - Milldale

Spectacular airport stay with pillowtop luxury, indoor pool, and hot tub retreat, just steps from a 24-hour fitness centre.

₹13,873 total

includes taxes & fees

22 Nov - 23 Nov

A rooftop terrace with tables and potted plants, overlooking a cityscape with a prominent tower and a bridge.

4. Four Seasons Hotel San Francisco at Embarcadero

Downtown San Francisco

Spectacular luxury in San Francisco with breathtaking city views, pillowtop beds, and personalised turndown service.

₹51,368 total

includes taxes & fees

4 Dec - 5 Dec

A large, multi-story hotel with a golf course and beach views.

5. The Ritz-Carlton, Half Moon Bay

Ocean Colony

Oceanfront opulence awaits at this five-star retreat with a championship golf course, full-service spa, and stunning coastal views.

₹96,535 total

includes taxes & fees

6 Dec - 7 Dec

A modern house with a large glass facade, outdoor seating area, and a swimming pool.

6. Cavallo Point

Sausalito

Historic luxury near Golden Gate Bridge offers spa treatments, two restaurants, and scenic views.

₹61,530 total

includes taxes & fees

6 Nov - 7 Nov

A grand entrance with a large archway, a staircase, and two wall-mounted light fixtures.

7. Hotel Drisco

Pacific Heights

Pacific heights luxury at its finest with boutique charm, elevated service, and a daily manager's reception.

₹65,361 total

includes taxes & fees

30 Nov - 1 Dec

A luxurious interior with a round dining table, green upholstered seating, and a central fountain.

8. The Westin St. Francis San Francisco on Union Square

Union Square

Historic luxury in Union Square with fitness centre, fine dining, and concierge services.

₹25,120 total

includes taxes & fees

20 Nov - 21 Nov

An outdoor dining area with a view of a vineyard and a lake.

9. The St. Regis San Francisco

Downtown San Francisco

Indulge in five-star elegance at this city centre San Francisco sanctuary offering an indoor pool, luxury bedding, and bespoke service.

₹54,825 total

includes taxes & fees

22 Nov - 23 Nov

A balcony with a view of a tall building, a tree, and a table with chairs.

10. The Huntington Hotel

Downtown San Francisco

Historic luxury awaits at Nob Hill's Huntington Hotel, offering spa indulgence, dining, and boutique elegance.

₹94,117 total

includes taxes & fees

6 Nov - 7 Nov

View all properties

Top South San Francisco Hotel Reviews

Four Seasons Hotel San Francisco at Embarcadero

Downtown San Francisco

10/10 Excellent

Stephen

A grand building with classical architecture, featuring columns, detailed carvings, and a large entrance.

The Ritz-Carlton, San Francisco

Downtown San Francisco

10/10 Excellent

Henry

Hotel Drisco

Pacific Heights

10/10 Excellent

Andrew

A rooftop terrace with outdoor seating, a view of the city skyline, and modern buildings in the background.

Four Seasons Hotel San Francisco

Downtown San Francisco

10/10 Excellent

Adam

The Huntington Hotel

Downtown San Francisco

10/10 Excellent

A fantastic return for a San Francisco icon We recently stayed for three nights at the newly reopened Huntington Hotel on Nob Hill, and we’re delighted to say it has been well worth the wait. The rooms are beautifully appointed, combining comfort with understated luxury, and the gym is one of the best hotel fitness facilities we’ve used. Every member of staff made us feel genuinely welcome, with exceptional service throughout our stay. A special thank you to the Head Concierge and the...

Mark

The St. Regis San Francisco

Downtown San Francisco

10/10 Excellent

Anonymous traveller

A fire feature with a modern design, surrounded by outdoor seating with cushions, and a view of the water and distant landscape.

Fairmont Heritage Place, Ghirardelli Square

Fisherman's Wharf

10/10 Excellent

Anonymous traveller

An outdoor dining area with stone walls, fire pits, and wooden tables and chairs.

Four Seasons Hotel Silicon Valley at East Palo Alto

East Palo Alto

10/10 Excellent

AMANDA

A historic building with ornate architectural details, large windows, and a well-lit entrance.

Sutter Mansion

Western Addition

10/10 Excellent

Staying in the Mansion was to experience living in San Francisco in the style and comfort of a bygone era. The building has been beautifully restored and the rooms furnished in keeping with it's history. Our room was extremely comfortable and spacious, the bed amazing! Breakfast was of high quality and the kitchen responded well to special requests and dietary needs. All members of staff were welcoming, always going the extra mile to make our stay comfortable and easy. For us the location was...

Deborah J

A restaurant with outdoor seating surrounded by a garden path and various plants.

Nobu Hotel Palo Alto

University South

10/10 Excellent

This hotel repeatedly exceeded expectations! Firstly, the room was really nice - big, clean, comfortable, nice decor, good shower (including the shampoo, etc). Secondly, you couldn't ask for a better location in Palo Alto. It's central, close to all the bars and restaurants, and very close to the Cal train. Finally - and this was what impressed me the most - the staff go above and beyond expectations unlike anywhere I've seen. They brought me surprise treats when I merely mentioned that I had a...

Joanna

Frequently Asked Questions

Are you searching for the perfect hotel for your luxury holiday in South San Francisco?

Let Expedia help you arrange your flight to San Francisco International Airport (SFO) airport or Oakland, CA (OAK-Oakland Intl.) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that South San Francisco offers. Known for its sightseeing and tours, South San Francisco also has some interesting things to see and do including San Francisco Bay, so you may want to take in the local sights during your visit.

When can I expect good weather in South San Francisco?

Planning for the weather is an important factor for making your trip to South San Francisco a success, especially when you're splurging. The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.

What's there to see and do in South San Francisco?

Take in some sights and attractions while you're in South San Francisco by visiting San Francisco Bay, Santa Cruz Mountains and South San Francisco Hillside Sign. If you have spare time during your trip, you might want to make a stop at See's Candies and San Bruno Point Park.

How can I get around South San Francisco?

It's easier to get around town in style when you know your options. Head to South San Francisco Metro Station to catch the metro. To see more of the larger area, hop on a train at South San Francisco Station.

Search Luxury Hotels in South San Francisco

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for South San Francisco luxury hotels

1. AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

2. San Francisco Airport Marriott Waterfront

3. The Westin San Francisco Airport

4. Four Seasons Hotel San Francisco at Embarcadero

5. The Ritz-Carlton, Half Moon Bay

6. Cavallo Point

7. Hotel Drisco

8. The Westin St. Francis San Francisco on Union Square

9. The St. Regis San Francisco

10. The Huntington Hotel

Top South San Francisco Hotel Reviews

Four Seasons Hotel San Francisco at Embarcadero

10/10 Excellent

Frequently Asked Questions

Are you searching for the perfect hotel for your luxury holiday in South San Francisco?

When can I expect good weather in South San Francisco?

What's there to see and do in South San Francisco?

How can I get around South San Francisco?

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