All Hotels by Ayres Collection in South San Diego - 2026 Updated Prices

A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

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Top South San Diego Hotel Reviews

Manchester Grand Hyatt San Diego

8/10 Good

"Beautiful view. Nice room."

Handlery Hotel

8/10 Good

"We stayed for 4 days and one of the days our room was not cleaned. There was also construction going on in the parking lot next to our room and the workers were using noisy machinery outside our window/room at 7:30am in the morning. Also an alarm for the entry door went off due to a battery that needed replaced at 6:30am in the morning. The staff were apologetic but this was our vacation and we wanted to sleep and come back from our meeting to a clean room."

Lafayette Hotel & Club

10/10 Excellent

"Unique hotel with a lot of nightlife! This felt like an adult playground. Explicit house music on at the pool, rooms with lot of alcohol and lots of bars. Not as much access to small bites after hours except in the diner where that menu was small. No food in lobby bar or jazz club. We walked around the neighborhood to see what else we could enjoy, but only found resturants. Loved Chance's coffee next door! We saw a few kids there, but I wouldn't bring kids under 21 there. My 21-year-old son was with me and agreed. Fun experience!!!"

The Dana on Mission Bay

10/10 Excellent

"It is a great place to stay. Very good location to visit a lot of places. Breakfast was great and the gift shop had great coffee. The rooms were nice and spacious and clean. The grounds were very nice to take a walk. I definitely work stay there again"

Bay Club Hotel & Marina

10/10 Excellent

"Love this place. The staff is wonderful and so friendly. We stay here once every year in September and will continue in the years to come."

The Sofia Hotel

10/10 Excellent

"My first hotel ever so all I can say the staff was very informative and attentive. I was told about the amenities and bar. The small gym was clean and nice for a light workout."

Wyndham San Diego Bayside

8/10 Good

"We didn’t have any washcloth size towels in our rooms. It would be nice if they were included. Not a big deal though, we really enjoyed our stay and will likely return in the future!"

Hard Rock Hotel San Diego

10/10 Excellent

"We had a wonderful stay at the Hard Rock Hotel San Diego. The amenities and overall experience made our anniversary trip feel extra special, and the thoughtful anniversary gift we received was such a lovely cherry on top! ❤️ The only area that could have used a little more attention was the room cleanliness, as some areas could have been dusted more thoroughly. Aside from that, we really enjoyed our stay and appreciated the hospitality and special touches that helped make our anniversary memorable."

Sheraton San Diego Resort

10/10 Excellent

"Staff from check-in to breakfast service were friendly and efficient. Dining area was clean as well as the property. I will definitely come back and recommend to others."

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Change your mind

Treat yourself

Be picky

Check prices for these dates

Top South San Diego Hotel Reviews

Manchester Grand Hyatt San Diego

Handlery Hotel

Lafayette Hotel & Club

The Dana on Mission Bay

Bay Club Hotel & Marina

The Sofia Hotel

Wyndham San Diego Bayside

Hard Rock Hotel San Diego

Sheraton San Diego Resort

Explore a world of travel with Expedia