An aerial view of a coastal landscape with a dam, farmland, and dense forests.

Santee Hotels from ₹5,443

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Filter by

Star rating

Guest rating

Our top choices for Santee hotels

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
United States
Victor
₹13,143
₹14,589 total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Santee

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
United States
sandra
₹11,179
₹12,408 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn Santee-I-95

3. Tru By Hilton Santee

Tru By Hilton Santee
Santee
United States
Connor
₹9,523
₹10,570 total
includes taxes & fees
22 Nov - 23 Nov
Tru By Hilton Santee

4. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Johnny
₹11,298
₹12,541 total
includes taxes & fees
22 Nov - 23 Nov
Best Western Plus Santee Inn

5. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Stephen
₹7,585
₹8,420 total
includes taxes & fees
1 Nov - 2 Nov
Baymont by Wyndham Santee

6. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
United States
santa
₹9,523
₹10,570 total
includes taxes & fees
22 Nov - 23 Nov
Comfort Inn & Suites Santee

7. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
United States
Traci
₹10,159
₹11,276 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Santee by IHG

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
United States
Robert
₹6,069
₹6,736 total
includes taxes & fees
29 Oct - 30 Oct
Travelodge by Wyndham Santee

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
United States
William
₹6,045
₹6,710 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Santee/I-95

10. Red Roof Inn Santee

Red Roof Inn Santee
Santee
United States
Sharyn
₹5,973
₹6,630 total
includes taxes & fees
8 Nov - 9 Nov
Red Roof Inn Santee

11. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
United States
Louis
₹5,165
₹6,207 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn & Suites Santee I-95

12. Econo Lodge Santee

Econo Lodge Santee
Santee
United States
Arthur
₹6,447
₹7,156 total
includes taxes & fees
17 Nov - 18 Nov
Econo Lodge Santee

13. Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
United States
Stevenson
₹7,349
₹8,157 total
includes taxes & fees
25 Oct - 26 Oct
Ramada by Wyndham Santee I-95

14. Ashburn Inn Manning I 95

Ashburn Inn Manning I 95
Manning
₹5,879
₹6,526 total
includes taxes & fees
2 Nov - 3 Nov
Ashburn Inn Manning I 95

15. Bells Marina & Resort

Bells Marina & Resort
Eutawville
United States
Mark
₹6,806
₹7,839 total
includes taxes & fees
1 Nov - 2 Nov
Bells Marina & Resort

16. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
Orangeburg
United States
Julie
₹9,592
₹10,647 total
includes taxes & fees
2 Nov - 3 Nov
Fairfield Inn by Marriott Orangeburg

17. Hampton Inn Manning

Hampton Inn Manning
Manning
United States
Clayton
₹13,312
₹14,776 total
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn Manning

18. Peach Tree Inn

Peach Tree Inn
St. George
United States
Linda
₹5,810
₹6,275 total
includes taxes & fees
1 Nov - 2 Nov
Peach Tree Inn

19. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
Orangeburg
United States
Henrietta
₹10,348
₹11,487 total
includes taxes & fees
2 Nov - 3 Nov
SpringHill Suites by Marriott Orangeburg

20. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
United States
Belinda
₹10,410
₹11,556 total
includes taxes & fees
8 Nov - 9 Nov
Tru by Hilton Orangeburg
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
See properties

Santee Cooper Country Club

7.8/10 (94 reviews)
This George Cobb-designed course winds through majestic pines with strategic doglegs and panoramic Lake Marion views. Enjoy the signature closing hole and well-maintained fairways perfect for golfers of all skill levels.
See properties

Santee National Golf Club

8.0/10 (74 reviews)
This championship course blends Lowcountry charm with highland terrain, featuring moss-draped oaks and pristine bunkers. Enjoy diverse play with wide-open front nine and wooded back nine challenges.
See properties

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

See all hotels in Santee
A tree with Spanish moss and autumn leaves in a body of water.

Top Santee Hotel Reviews

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Staff was friendly upon arrival and it was easy to check in. Rooms were clean and quiet with an amazing amount of room for an affordable price"
Deb 1-night trip
Posted 1 hour ago
Comfort Inn & Suites Santee
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

10/10 Excellent
"We stay here every year as we travel from Florida to Virginia. We travel w a small dog, so our choices are limited, but this hotel is a great stop. The rooms are like new; clean, fresh, and comfortable. Also quiet between floors. The breakfast is ok, typical "free breakfast" fare, but it is hot and fresh, and we are always grateful for the hot coffee 22/7."
Laura 1-night trip
Posted 14 hours ago
Tru by Hilton Orangeburg
Baymont by Wyndham Santee

Baymont by Wyndham Santee

8/10 Good
"2nd stay here"
Stephen 1-night trip
Posted 19 hours ago
Baymont by Wyndham Santee
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

10/10 Excellent
"Great option. Quiet and clean. Staff was so nice. Great location. Very satisfied."
Nakia 4-night trip
Posted 1 day ago
Spark by Hilton Orangeburg
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The room we stayed in was clean.The only downside was that they were doing some remodeling to the place and a worker knocked on our door for some reason, don't know why he didn't speak English."
Dawn 1-night trip
Posted 2 days ago
Ramada by Wyndham Santee I-95
Red Roof Inn Santee

Red Roof Inn Santee

8/10 Good
"Everything was adequate or good."
Sharyn 1-night trip
Posted 4 days ago
Red Roof Inn Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Excellent place to visit and friendly people"
Raymond 1-night trip
Posted 7 days ago
Hampton Inn Santee-I-95
Bells Marina & Resort

Bells Marina & Resort

8/10 Good
"Enjoyed our time there. On a beautiful cove of the lake."
Annette 1-night trip
Posted 3 weeks ago
Bells Marina & Resort

More cheap stays in Santee

Red Roof Inn Orangeburg

Red Roof Inn Orangeburg

3691 Saint Matthews Rd Orangeburg SC
₹5,546
₹6,157 total
2 Nov - 3 Nov
includes taxes & fees
Red Roof Inn Orangeburg
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

3608 Saint Matthews Rd Orangeburg SC
₹5,547
₹6,158 total
25 Oct - 26 Oct
includes taxes & fees
Super 8 by Wyndham, Orangeburg
Baymont by Wyndham Santee

Baymont by Wyndham Santee

249 Britain Street Santee SC
₹7,585
₹8,420 total
1 Nov - 2 Nov
includes taxes & fees
8/10 Very good! (1,495 reviews)
Baymont by Wyndham Santee
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2816 Paxville Highway Manning SC
₹8,027
₹8,910 total
8 Nov - 9 Nov
includes taxes & fees
SureStay Hotel by Best Western Manning
Tru By Hilton Santee

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC
₹9,523
₹10,570 total
22 Nov - 23 Nov
includes taxes & fees
Tru By Hilton Santee
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

739 Citadel Road Orangeburg SC
₹10,410
₹11,556 total
8 Nov - 9 Nov
includes taxes & fees
9.2/10 Wonderful! (1,003 reviews)
Tru by Hilton Orangeburg

Find out more about Santee

Top reasons to visit Santee

  • Outdoor Adventures: Santee is a paradise for outdoor enthusiasts, featuring Santee State Park and picturesque lakes for hiking, fishing, and picnicking.
  • Golfing Opportunities: The area boasts several golf courses, making it a prime destination for golf lovers seeking a leisurely game.
  • Charming Accommodation: A variety of hotels and inns cater to different preferences, ensuring a comfortable stay for all visitors.
  • Community Spirit: Experience the warmth of friendly locals and a welcoming atmosphere throughout your visit.
  • Day Trip Excursions: Santee offers convenient access to delightful day trips, enhancing your vacation experience.

Find great hotels in and around Santee

In Santee, South Carolina, you'll discover a diverse selection of hotels and motels, catering to various preferences and needs. From pet-friendly accommodations to welcoming spaces for LGBTQIA travellers, Santee offers an inviting atmosphere for all. Whether you're seeking the comfort of a Hilton hotel or the charm of local inns, you're sure to find the perfect spot for your stay in this delightful destination.

  • Baymont by Wyndham Santee: A budget-friendly hotel located in the heart of Santee, Baymont by Wyndham offers a welcoming atmosphere for both business and leisure travellers. Its pet-friendly policy allows guests to bring their furry companions, with amenities tailored to ensure a comfortable stay. The hotel features essential amenities such as complimentary breakfast, free Wi-Fi, and a fitness centre, catering to the needs of both business travellers and holidaymakers alike. The inviting ambience and reasonable rates make it a practical choice for those seeking convenient lodging while exploring the region.
  • Fairfield Inn by Marriott Orangeburg: Situated 31km from Santee, the Fairfield Inn by Marriott Orangeburg is ideal for those in search of a reliable and comfortable lodging experience. This budget-friendly hotel boasts a commendable guest rating of 8.4 out of 10, reflecting its quality service and amenities. Guests can enjoy a complimentary breakfast, free high-speed internet access, and a well-equipped fitness centre. The property is especially suited for business travellers, providing a conducive environment for work while still being within easy reach of Santee's attractions.
  • Best Western Plus Santee Inn: Located in Santee and boasting a guest rating of 8.8 out of 10, the Best Western Plus Santee Inn combines comfort and convenience for both pet owners and business travellers. With a range of amenities, including a dog exercise area and a pet-friendly policy, guests can feel at home with their pets. The hotel also offers complimentary breakfast, free Wi-Fi, and a refreshing outdoor pool. Its welcoming atmosphere and excellent service make it an attractive option for anyone looking to explore Santee while enjoying modern comforts.

Where to stay near Santee

Santee, South Carolina, offers a delightful blend of outdoor adventures and serene landscapes, perfect for a romantic getaway or a family-friendly holiday. As you explore this charming city, you'll encounter friendly locals and a welcoming atmosphere. Nearby attractions provide an exciting mix of experiences, ensuring a comfortable and memorable stay. Embrace the vibrant community spirit and enjoy a budget-friendly escape while discovering the best of Santee and its surrounding regions.

  • Summerton: Located 18km from Santee, this charming city offers a blend of outdoor activities and stunning scenery. Visitors often flock here for a romantic getaway, with highlights including its recreational areas and picturesque golf courses. Nature lovers will appreciate the nearby lake and national state park, providing ample opportunities for exploration and relaxation. The best time to visit is during the peak seasons of March to April and July, when Summerton truly comes alive with visitors seeking its serene landscapes.
  • Vance: Just 8km away from Santee, Vance is a seasonal hotspot for travellers, particularly in March to April and July. Known for its captivating outdoor experiences and romantic settings, this city features delightful recreational areas and golf courses. The local attractions, including a stunning lake, a national state park, and a nearby beach, make Vance an excellent destination for those looking to immerse themselves in nature. However, be mindful of the off-peak months, such as February, October, and December, when visitor numbers dwindle.
  • Elloree: Situated 10km from Santee, Elloree offers a wonderful escape with a consistent flow of visitors throughout the year. The city attracts those in search of outdoor adventures and scenic beauty, with popular spots including golf courses and recreational areas. Visitors can also enjoy the nearby lake, national state park, and urban park, making Elloree an ideal location for those wishing to unwind amidst nature. Peak months, such as March, July, and September, draw the most travellers, ensuring a vibrant atmosphere.

Things to do in Santee

Shopping

In Santee, visit the local shops for unique gifts and souvenirs. If you're up for a drive, head to the nearby Orangeburg Mall, located approximately 32km away, which features a variety of retail stores and dining options for a broader shopping experience.

Recreation

The Santee State Park offers tranquil hiking trails, scenic views of Lake Marion, and opportunities for birdwatching. Enjoy peaceful picnics amidst nature or unwind with fishing and kayaking. Nearby, the Santee Cooper Resort provides relaxing spa services to rejuvenate your mind and body.

Adventure

Santee State Park offers a variety of outdoor activities, including hiking trails that wind through scenic woodlands and opportunities for fishing and boating on Lake Marion. Explore the natural beauty while enjoying the peaceful surroundings, ideal for an adventurous day out in nature.

For a thrilling experience, visit the Santee Cooper Lakes region, known for its excellent bass fishing and water sports. Engage in kayaking or jet skiing to explore the expansive waters while soaking up the sun.

Golf enthusiasts can enjoy the challenging courses at the Santee Cooper Resort, where picturesque views and well-maintained greens provide a delightful golfing experience amid tranquil nature.

Nightlife

Santee offers a relaxed nightlife atmosphere with venues like the Lake Marion Golf Club, which hosts casual evenings of camaraderie and local tunes. Nearby, the various lakeside bars provide a charming setting for enjoying drinks and live music, making for a pleasant end to your day.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santee

To save money on your trip to Santee, consider visiting between December and February, when accommodation prices are at their lowest. Look for free activities like Taw Caw Creek and take advantage of public transport options such as buses or bikes. Booking on a Monday can also help reduce costs, as Saturdays tend to be the most expensive. Use Expedia’s search tool to find budget-friendly hotels, and consider package deals that combine flights and activities for additional savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to specify your budget, ideal location, and additional preferences. You can arrange your search results to display prices from lowest to highest, allowing you to find the most affordable hotels first. Furthermore, you have the option to refine your choices by hotel type; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that you can book.
  • Consider bundling your trip: You can potentially save money by combining your hotel reservation in Santee with your flights and activities by opting for an Expedia package.

Find the best attractions near Santee

Santee, South Carolina, is an ideal destination for outdoor enthusiasts and couples seeking a picturesque getaway. The area boasts a variety of attractions, including Santee State Park, Santee Lakes, Santee Boulders, and the Santee Sportsplex, perfect for those looking to enjoy nature, beaches, and cultural experiences. With its stunning landscapes and recreational opportunities, Santee promises a memorable vacation for all visitors.

  • Taw Caw Creek: Located 14km from Santee, Taw Caw Creek offers a serene lake experience with beautiful scenery and a sandy beach. It's an ideal spot for outdoor activities and romantic strolls, making it perfect for those seeking relaxation amidst nature.
  • Santee Indian Mound and Fort Watson Site: Just 6km from Santee, this historic site is rich in culture, showcasing the area's indigenous heritage. Visitors can explore the ancient mound and learn about its significance in local history, providing a unique glimpse into the past.
  • Goat Island: Situated 14km from Santee, Goat Island is a tranquil escape featuring picturesque beaches and outdoor leisure opportunities. It’s an excellent destination for picnics, birdwatching, or simply enjoying the natural beauty of the surroundings.

Best time to go to Santee

The best time to visit Santee is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighAverage
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighSlightly High
May72.0°F (22.2°C)Light RainMostly SunnyAverageSlightly High
June78.6°F (25.9°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighAverage
August79.9°F (26.6°C)Light RainMostly SunnyAverageAverage
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowSlightly High
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Santee

Flying into Santee, South Carolina, is convenient with three major airports nearby. Charleston International Airport (CHS) is located 79km away, with luxurious hotels like The Charleston Place, Hotel Bennett, and The Dewberry Charleston, all offering transfer services. MYRtle Beach International Airport (MYR), situated 145km from Santee, features options such as the Marriott Myrtle Beach Resort & Spa and Hilton Grand Vacations Club Ocean Enclave. Lastly, Columbia Metropolitan Airport (CAE) is also 79km away, with hotels like Graduate by Hilton and Doubletree by Hilton providing easy access to the airport. Each hotel is well-connected, ensuring a smooth transition to your destination.

Frequently asked questions

Where is the best place for a stay in Santee?
Based on our traveller data, Tru By Hilton Santee is one of the top choices for your stay. This hotel offers free breakfast and an indoor pool. Other good choices for your visit include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee. See all available top hotels, or vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Tru By Hilton Santee is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Two other good options for you and your pet include Baymont by Wyndham Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee/I-95. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 153 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee State Park and Lake Marion. A couple of additional sights to add to your itinerary are Santee National Golf Club and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

Explore a world of travel with Expedia