Otay Mesa Travel Guide
San Diego
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Top hotels in Otay Mesa
Paradise Point Resort & Spa
Paradise Point is a very nice, clean, property. The staff are all very helpful. There are lots of things to do on site and the restaurants are excellent. Nice beaches you can walk to and plenty of scenery without ever leaving the resort. Would definitely stay here again.
Reviewed on 22 Mar 2026
Best Western Seven Seas
Appreciate the free parking!
Reviewed on 23 Mar 2026
Hard Rock Hotel San Diego
Stay was great. Fast check-in. I did wish they could approve our late checkout. We ran the SD half marathon and had limited time to get cleaned up before check out. That was a bit stressful
Reviewed on 23 Mar 2026
Handlery Hotel
Yes
Reviewed on 22 Mar 2026
The DEXTRO Little Italy, BW Premier Collection
Yes
Reviewed on 22 Mar 2026
Days Inn by Wyndham San Diego Hotel Circle
We had a great two-day stay in San Diego! The hotel is beautiful and the rooms were very clean and spacious enough for four adults. We especially appreciated the excellent handicap parking, which made arrivals much easier. The only downsides were that our room door (277) was quite heavy and hard ...
Reviewed on 23 Mar 2026
Other neighbourhoods around Otay Mesa
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
