Otay Mesa Travel Guide
San Diego
Visit Otay Mesa
Stay near popular Otay Mesa attractions
Top hotels in Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
"Happy with are stay"
Reviewed on 11 Aug 2026
Paradise Point Resort & Spa
"Waterfall pool was not clean"
Reviewed on 12 Aug 2026
Manchester Grand Hyatt San Diego
"Don’t book here at all. I booked this place for a honeymoon and a nice room, only to be told on day of arrival that"
Reviewed on 12 Aug 2026
Wyndham San Diego Bayside
"The view was perfect"
Reviewed on 12 Aug 2026
The Dana on Mission Bay
"It was a very nice place to stay for a couple of days. Very close to lots to do. You can catch an Uber or drive because it was central to lots of things. I would recommend this place. One downfall is having to pay for parking. That is my only complaint and wish I had seen that but because I reserved ..."
Reviewed on 12 Aug 2026
Hard Rock Hotel San Diego
Where to stay in Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Nova SD – discover Gaslamp Quarter, a destination also famous for its shopping.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
