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Check prices for these dates

Tonight
9 Nov - 10 Nov
Tomorrow
10 Nov - 11 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Our top choices for Otay Mesa West LGBT-friendly hotels

A Hampton Inn & Suites hotel with a modern facade, large windows, and a covered entrance area.

1. Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
Mar Vista
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place to stay in imperial beach. Would stay here again."
United States
Joshua
The price is ₹13,890
₹15,861 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Imperial Beach San Diego
A hotel with a prominent bell tower, a covered entrance, and a well-lit facade.

2. La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1,795 reviews)
"Clean room , friendly staff , always helpful, breakfast good , always great to return"
United States
Luis
The price is ₹9,739
₹10,713 total
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn by Wyndham San Diego Chula Vista
A Holiday Inn Express hotel with a covered entrance, multiple windows, and a palm tree in the foreground.

3. Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
Chula Vista
9.4 out of 10, Exceptional, (1,654 reviews)
"Great stay"
United States
Daniel
The price is ₹14,932
₹16,425 total
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Express San Diego South - Chula Vista by IHG
A swimming pool adjacent to a multi-story building with balconies, a lifeguard stand, and a no diving sign.

4. Days Inn by Wyndham Chula Vista/San Diego

Days Inn by Wyndham Chula Vista/San Diego
3.0 star property
Chula Vista
7.0 out of 10, Good, (1,321 reviews)
"Stayed here a few times and staff has always treated me well"
United States
Brian
The price is ₹8,030
₹8,849 total
includes taxes & fees
16 Nov - 17 Nov
Days Inn by Wyndham Chula Vista/San Diego
A modern hotel room with a grey sectional sofa, a wooden armchair, a beige ottoman, and a bed with a blue headboard. There are framed pictures on the wall and a view of the outdoors through large windows.

5. Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center
4.0 star property
Chula Vista
8.8 out of 10, Excellent, (703 reviews)
"I had a wonderful stay at the Gaylord! Everything was great, and I have no complaints. The restaurants were excellent, and having Starbucks downstairs was amazing—a perfect way to start the morning. I really enjoyed my visit and would happily stay again!"
United States
Joane
The price is ₹26,296
₹34,245 total
includes taxes & fees
29 Nov - 30 Nov
Gaylord Pacific Resort & Convention Center
A hotel room with a bed, a sofa, a desk, and a window with curtains.

6. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (4,230 reviews)
"Great property, friendly staff and a restaurant with good food and live music next door. Had an excellent time!"
United States
Candas
The price is ₹12,595
₹13,879 total
includes taxes & fees
29 Nov - 30 Nov
Best Western Plus Marina Gateway Hotel
A courtyard with palm trees, a brick pathway, and a building with a tiled roof.

7. Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista
3.0 star property
Otay Ranch
9.4 out of 10, Exceptional, (643 reviews)
"Wonderful accommodations, delicious breakfast, friendly staff, convenient location."
United States
Leslie
The price is ₹17,686
₹19,489 total
includes taxes & fees
30 Nov - 1 Dec
Residence Inn by Marriott San Diego Chula Vista
A marina with numerous boats docked, surrounded by buildings and a city skyline in the background.

8. Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.6 out of 10, Excellent, (3,814 reviews)
"Comfortable stay with beautiful views"
United States
Solair
The price is ₹10,894
₹17,272 total
includes taxes & fees
22 Nov - 23 Nov
Sheraton San Diego Resort
A modern high-rise building with a grid of windows and a flat facade.

9. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,262 reviews)
"Amazing stay! Would definitely come back!"
United States
Dirosia
The price is ₹13,523
₹15,680 total
includes taxes & fees
22 Nov - 23 Nov
Marriott Vacation Club®, San Diego
A building named "The Davis" with a modern facade, a brick base, and a staircase leading to the entrance.

10. The Davis Downtown San Diego

The Davis Downtown San Diego
3.5 star property
Downtown San Diego
8.0 out of 10, Very good, (635 reviews)
"Great hotel! Easy to use! Great price and location!"
United States
Robert Scott
The price is ₹6,977
₹7,936 total
includes taxes & fees
26 Nov - 27 Nov
The Davis Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Otay Mesa West

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A Hampton Inn & Suites hotel with a modern facade, large windows, and a covered entrance area.
Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
9.4
Exceptional
1,001 reviews
View
A hotel with a prominent bell tower, a covered entrance, and a well-lit facade.
La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
8.6
Excellent
1,795 reviews
View
A Holiday Inn Express hotel with a covered entrance, multiple windows, and a palm tree in the foreground.
Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
9.4
Exceptional
1,654 reviews
View
A swimming pool adjacent to a multi-story building with balconies, a lifeguard stand, and a no diving sign.
Days Inn by Wyndham Chula Vista/San Diego
3.0 star property
7.0
Good
1,321 reviews
View
A modern hotel room with a grey sectional sofa, a wooden armchair, a beige ottoman, and a bed with a blue headboard. There are framed pictures on the wall and a view of the outdoors through large windows.
Gaylord Pacific Resort & Convention Center
4.0 star property
8.8
Excellent
703 reviews
View

Top Otay Mesa West Hotel Reviews

A Hampton Inn & Suites hotel with a modern facade, large windows, and a covered entrance area.
Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
Mar Vista

10/10 Excellent

Very clean room and spacious
United Kingdom
David
Reviewed January 13, 2026
Hampton Inn & Suites Imperial Beach San Diego

Frequently Asked Questions

Looking for a gay-friendly hotel in Otay Mesa West?

If you’re looking for a place that will welcome you to Otay Mesa West, Expedia has all the gay-friendly hotels you'd wish for. Discover the people, places and traditions found only in Otay Mesa West.

What are the top places to visit in Otay Mesa West?

During your trip, get out and enjoy everything Otay Mesa West has to offer. You and your travelling companions may want to visit San Diego Zoo, Mission Bay and San Ysidro Border Crossing. While you're here, capture some great memories of your trip with stops at Petco Park, Port of San Diego and Marine Corps Recruit Depot.

What is a gay-friendly hotel in Otay Mesa West?

LGBTQ-friendly hotels welcome all travellers who identify as LGBTQIA+. Expedia has worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of LGBTQ-friendly hotels worldwide. In Otay Mesa West, hotels affiliated with IGLTA prioritise a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.

What can I expect from a gay-friendly hotel in Otay Mesa West?

Take a holiday from the ordinary; stay at a gay-friendly hotel in Otay Mesa West, and you’ll be around like-minded people, so you can relax and enjoy your trip. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.

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