Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Top hotels in Otay Mesa West
Hampton Inn & Suites by Hilton San Diego SeaWorld
Reviewed on 15 Oct 2025
Manchester Grand Hyatt San Diego
Reviewed on 20 Oct 2025
Comfort Inn San Diego Airport At The Harbor
Reviewed on 19 Oct 2025
Handlery Hotel
Reviewed on 19 Oct 2025
Wyndham San Diego Bayside
Reviewed on 20 Oct 2025
Pendry San Diego
Reviewed on 15 Oct 2025
Other neighbourhoods around Otay Mesa West
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Mid-City
While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Otay Mesa West Travel Guide
- Places of interest
- Hotels in top San Diego neighborhoods
- Search Otay Mesa West Hotel Brands
- More trip options
- San Diego Zoo
- Mission Bay
- San Ysidro Border Crossing
- Petco Park
- Balboa Park
- San Diego State University
- Hotel Circle
- USS Midway Museum
- Marine Corps Recruit Depot
- Hotel del Coronado
- Coronado Beach
- Seaport Village
- Old Town San Diego State Park
- Waterfront Park
- Fashion Valley Mall
- North Island Credit Union Amphitheatre
- Shelter Island
- Belmont Park
- Mission Bay Park
Hotels Near Otay Mesa West, San Diego
Search Otay Mesa West Hotel Brands
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