Visit Otay Mesa West
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Top hotels in Otay Mesa West
Bay Club Hotel & Marina
It was great
Reviewed on 6 Dec 2025
Legacy Resort Hotel & Spa
The room was very clean.
Reviewed on 1 Dec 2025
Hard Rock Hotel San Diego
Room was clean and staffs were courteous.
Reviewed on 4 Dec 2025
The DEXTRO Little Italy, BW Premier Collection
Mostly everything was great but the a/c wall unit was controlled by the wall thermostat but no matter what temp you set it at or even turn it off it runs 24/7, making the room like a refrigerator
Reviewed on 1 Dec 2025
Hampton Inn San Diego/Mission Valley
Spacious and clean rooms, helpful staff
Reviewed on 2 Dec 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
Very clean!
Reviewed on 2 Dec 2025
Other neighbourhoods around Otay Mesa West
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Marina District
Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Otay Mesa West Travel Guide
- Places of interest
- Hotels in top San Diego neighborhoods
- Search Otay Mesa West Hotel Brands
- More trip options
- San Diego Zoo
- Mission Bay
- San Ysidro Border Crossing
- Balboa Park
- Petco Park
- Hotel Circle
- Hotel del Coronado
- Marine Corps Recruit Depot
- Coronado Beach
- Seaport Village
- USS Midway Museum
- San Diego State University
- Old Town San Diego State Park
- Waterfront Park
- Fashion Valley Mall
- Shelter Island
- San Diego-Coronado Bridge
- Belmont Park
Hotels Near Otay Mesa West, San Diego
Search Otay Mesa West Hotel Brands
Expedia's Latest Trends
- Hotels with Early Check-in in Hollywood
- Resorts Karur
- Hotels in Fisherman's Wharf
- Cheap Hotels in Downtown Los Angeles
- 5 Star Hotels in Fatehabad Road
- Hotels in Downtown San Francisco
- Resorts Bengaluru
- Hotels in Ratanada
- Four Leaf Service Suites
- Hotels in Union Square
- Hotels in Downtown Los Angeles
- Hotels in Hollywood
- Park Plaza Delhi CBD Shahdara
