Search Hotels in Mission Bay, San Diego

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Our top choices for Mission Bay hotels

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1572)
"Loved our stay "
United States
Jeremy
The price is ₹11,664
₹18,192 total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Mission Bay Spa and Marina

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1311)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
The price is ₹10,639
₹16,305 total
includes taxes & fees
16 Dec - 17 Dec
San Diego Mission Bay Resort

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay
9.0 out of 10, Wonderful, (3925)
"Always love staying here. Staff was very courteous and the rooms very clean. "
United States
Eric
The price is ₹12,569
₹16,255 total
includes taxes & fees
16 Dec - 17 Dec
The Dana on Mission Bay

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2353)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is ₹11,696
₹18,229 total
includes taxes & fees
16 Dec - 17 Dec
Paradise Point Resort & Spa

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
8.2 km from Mission Bay
8.8 out of 10, Excellent, (738)
"Friendly staff and clean rooms. "
Canada
Justine
The price is ₹9,331
₹10,819 total
includes taxes & fees
28 Dec - 29 Dec
The DEXTRO Little Italy, BW Premier Collection

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 10 km from Mission Bay
8.6 out of 10, Excellent, (1865)
"Enjoyed my stay"
United States
Brandon
The price is ₹9,337
₹15,262 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
8 km from Mission Bay
8.4 out of 10, Very good, (6064)
"Always an amazing stay"
United States
Jana
The price is ₹12,220
₹16,791 total
includes taxes & fees
17 Dec - 18 Dec
Wyndham San Diego Bayside

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
6 km from Mission Bay
8.2 out of 10, Very good, (3183)
"Great stay! "
United States
Melissa
The price is ₹10,127
₹14,896 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sheraton San Diego Resort

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 9.4 km from Mission Bay
9.4 out of 10, Exceptional, (1003)
"Great location "
United States
Mohammad
The price is ₹7,726
₹11,572 total
includes taxes & fees
23 Dec - 24 Dec
Staypineapple, Hotel Z, Gaslamp San Diego

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
8.5 km from Mission Bay
8.6 out of 10, Excellent, (1064)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is ₹12,225
₹16,796 total
includes taxes & fees
21 Dec - 22 Dec
The Westin San Diego Bayview

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
8.7 km from Mission Bay
8.6 out of 10, Excellent, (1452)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 9.2 km from Mission Bay
9.2 out of 10, Wonderful, (1949)
"Great hotel"
United States
Farzana
The price is ₹14,377
₹21,425 total
includes taxes & fees
21 Dec - 22 Dec
Marriott Marquis San Diego Marina

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
2.6 km from Mission Bay
7.4 out of 10, Good, (4114)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is ₹7,645
₹8,788 total
includes taxes & fees
21 Dec - 22 Dec
Wyndham Garden San Diego Near SeaWorld

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
7 km from Mission Bay
8.8 out of 10, Excellent, (1559)
"Staff was great, easy check in and great location"
United States
Alysa
The price is ₹10,344
₹11,890 total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Island Palms Hotel & Marina

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 17.8 km from Mission Bay
8.4 out of 10, Very good, (1886)
"Excellent location"
United States
Paolo
The price is ₹9,082
₹10,348 total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 9 km from Mission Bay
9.0 out of 10, Wonderful, (2872)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is ₹15,914
₹23,379 total
includes taxes & fees
16 Dec - 17 Dec
Manchester Grand Hyatt San Diego

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
6.8 km from Mission Bay
9.2 out of 10, Wonderful, (3186)
"Great stay and location!"
United States
Jason
The price is ₹11,230
₹12,909 total
includes taxes & fees
4 Jan - 5 Jan 2026
Bay Club Hotel & Marina

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
4.3 km from Mission Bay
8.8 out of 10, Excellent, (1286)
"Hotel was very clean and the staff was very friendly"
United States
Norma
The price is ₹8,536
₹9,811 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 4 km from Mission Bay
8.2 out of 10, Very good, (1915)
"Efficient check in, clean rooms and great breakfast."
Canada
Wendy
The price is ₹7,302
₹8,393 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 9.6 km from Mission Bay
9.0 out of 10, Wonderful, (1229)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is ₹12,395
₹14,371 total
includes taxes & fees
17 Dec - 18 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mission Bay

Find the best Mission Bay areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Mission Bay Hotel Reviews

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Frequently asked questions

What is Mission Bay like?
You'll be sure to have fun exploring San Diego's Mission Bay neighbourhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighbourhood.
What's a favourite hotel to stay in Mission Bay?
Based on Expedia customer reviews, Paradise Point Resort & Spa is the highest ranked property in Mission Bay. This resort offers a marina and 5 outdoor pools. Other favourite options in the area include San Diego Mission Bay Resort and The Dana on Mission Bay.
How many hotels should I expect to find in the Mission Bay area?
If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals in Mission Bay.
What is there to do around this San Diego neighbourhood?
Enjoy a stroll along the shore at Mission and Pacific Beaches, Ski Beach and Crown Point Shores while you're in Mission Bay. You could also plan a visit to Mission Bay or Mission Bay Golf Course while you're in the neighbourhood. Hotel Circle, North Cove Beach and Bahia Point Beach are just a few of the places to visit in and around Mission Bay. When you're sightseeing in San Diego, Bay City Brewing Co. and Sail Bay are also worth a stop.