What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

The Best Hotels in Main Street, Ann Arbor - 2026 Updated Prices

Ann Arbor, Michigan, USA Downtown Panorama

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Main Street hotels

Standard Single Room, 1 Bedroom | Bathroom | Towels, soap

Your Motel

13.3 km from Main Street

Martez

₹7,001 total

includes taxes & fees

22 Jun - 23 Jun

Presidential Suite, 1 King Bed with Sofa bed, Non Smoking | Living area | Flat-screen TV, video game console, pay films

Wingate by Wyndham Brighton

29.7 km from Main Street

Stephen

₹5,785 total

includes taxes & fees

5 Jul - 6 Jul

Country Meadow inn

23.7 km from Main Street

Gordon

₹8,098 total

includes taxes & fees

22 Jun - 23 Jun

Stadium Suites

2.5 km from Main Street

Fadi

₹12,228 total

includes taxes & fees

5 Jul - 6 Jul

Studio Suite, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds

Days Inn by Wyndham Whitmore Lake/Ann Arbor/Brighton

16.5 km from Main Street

Ashley

₹8,387 total

includes taxes & fees

22 Jun - 23 Jun

The Clinton Inn

29.7 km from Main Street

₹15,054 total

includes taxes & fees

22 Jun - 23 Jun

Wyndham Garden Ann Arbor

3.2 km from Main Street

Darrow

₹7,455 total

includes taxes & fees

5 Jul - 6 Jul

Ann Arbor North Inn

5.6 km from Main Street

Teresa

₹6,408 total

includes taxes & fees

3 Jul - 4 Jul

Deluxe Room, 2 Queen Beds, Non Smoking | Desk, free cots/infant beds, free WiFi, bed sheets

Red Roof Inn Ann Arbor - U of Michigan South

Bryant Pattengill East, 4.8 km from Main Street

Yvonne

₹6,742 total

includes taxes & fees

4 Jul - 5 Jul

Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi

Baymont by Wyndham Milan

21.4 km from Main Street

Courtney

₹9,977 total

includes taxes & fees

22 Jul - 23 Jul

Travelodge by Wyndham Livonia/Canton/Novi Detroit Area

29.6 km from Main Street

Nam D.H.

₹6,175 total

includes taxes & fees

28 Jun - 29 Jun

Residence Inn By Marriott Ann Arbor South

Bryant Pattengill West, 5.5 km from Main Street

₹16,858 total

includes taxes & fees

28 Jun - 29 Jun

Ann Arbor Regent Hotel & Suites

6.6 km from Main Street

Shana

₹11,178 total

includes taxes & fees

23 Jun - 24 Jun

La Quinta Inn by Wyndham Detroit Canton

25.2 km from Main Street

carlos

₹6,496 total

includes taxes & fees

28 Jun - 29 Jun

Standard Room, 1 King Bed | Jetted bathtub

Days Inn by Wyndham Ann Arbor

6.4 km from Main Street

Charlie

₹7,225 total

includes taxes & fees

22 Jun - 23 Jun

Quality Inn & Suites Ann Arbor Hwy 23

6.4 km from Main Street

Claudia

₹8,848 total

includes taxes & fees

24 Jun - 25 Jun

Hampton Inn & Suites Detroit-Canton

25.2 km from Main Street

Tiffani

₹8,901 total

includes taxes & fees

2 Jul - 3 Jul

Spark by Hilton Ann Arbor South

Bryant Pattengill East, 4.8 km from Main Street

Michael

₹8,863 total

includes taxes & fees

28 Jun - 29 Jun

In-room safe, desk, laptop workspace, blackout curtains

Red Roof Inn PLUS+ Ann Arbor - U of Michigan North

5.4 km from Main Street

Marcus

₹5,712 total

includes taxes & fees

22 Jun - 23 Jun

Candlewood Suites Brighton by IHG

29.2 km from Main Street

Benjamin

₹9,110 total

includes taxes & fees

29 Jun - 30 Jun

View all properties

Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

South Central

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

See properties

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Kempf House Museum are top sights worth seeing.

See properties

A river with a bridge, surrounded by autumn foliage and a small island.

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

See properties

Aerial View of Burton Memorial Tower in Ann Arbor Campus

Old West Side

If you're looking for some top things to see and do in Old West Side and surrounding area, you can visit Ann Arbor Hands On Museum and University of Michigan Museum of Art.

See properties

Central Campus Medical

While visiting Central Campus Medical, you might make a stop by sights like Exhibit Museum of Natural History at the University Of Michigan and Hill Auditorium.

See properties

Top Main Street Hotel Reviews

Spark by Hilton Ann Arbor South

10/10 Excellent

"Room and bed were very comfortable and modern and clean. Pool was really nice size and exercise room was also very nicely equipped. The only negatives were that the elevator was a bit slow and the breakfast options were good but not as many hot options as we've seen at most chains. (Really, the toaster provided the only hot options.). But the yogurt dispenser was something we hadn't seen before and kinda fun with the toppings offered."

Weber's Hotel & Restaurant

10/10 Excellent

"Very clean, great design for draining in pool area, no stuffiness or cobwebs not even on the very high ceilings. It is obvious that cleanliness is a top priority throughout the hotel. Dinner in the restaurant was amazing, between the three of us we had a lot and everything was world class! Our service was also very top notch! We are well traveled and were very impressed….definitely will be back. I will say, replacing the old wood paneling look in the hallways and new register vents would make a big difference in appearance."

Search Hotels in Main Street, Ann Arbor

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Guest rating

Star rating

Our top choices for Main Street hotels

Your Motel

Wingate by Wyndham Brighton

Country Meadow inn

Stadium Suites

Days Inn by Wyndham Whitmore Lake/Ann Arbor/Brighton

The Clinton Inn

Wyndham Garden Ann Arbor

Ann Arbor North Inn

Red Roof Inn Ann Arbor - U of Michigan South

Baymont by Wyndham Milan

Travelodge by Wyndham Livonia/Canton/Novi Detroit Area

Residence Inn By Marriott Ann Arbor South

Ann Arbor Regent Hotel & Suites

La Quinta Inn by Wyndham Detroit Canton

Days Inn by Wyndham Ann Arbor

Quality Inn & Suites Ann Arbor Hwy 23

Hampton Inn & Suites Detroit-Canton

Spark by Hilton Ann Arbor South

Red Roof Inn PLUS+ Ann Arbor - U of Michigan North

Candlewood Suites Brighton by IHG

Where to stay in Main Street

South Central

Downtown

Bryant Pattengill East

Old West Side

Central Campus Medical

Top Main Street Hotel Reviews

Spark by Hilton Ann Arbor South

Frequently asked questions

Explore a world of travel with Expedia