South Central Houston Travel Guide
Houston
Visit South Central Houston
Popular places to visit
MD Anderson Cancer Center
If MD Anderson Cancer Center is what brings you to town, hopefully you'll have a chance to explore more of Houston.
Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed art galleries and great live music.
Houston Zoo
With a huge collection of animals, a water park and a cinema, Houston Zoo is a great day out for the family.
University of Houston
Take a campus tour or just explore the area of University of Houston during your travels in Houston. Experience the acclaimed theatre scene and lively festivals in this vibrant area.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's entertainment choices and acclaimed theatre scene.
Houston Methodist Hospital
If Houston Methodist Hospital is what brings you to town, hopefully you'll have a chance to explore more of Houston.
Top hotels in South Central Houston
Hotel Zaza Houston Museum District
Excellent experience!
Reviewed on 22 Apr 2026
Hilton Houston Plaza/Medical Center
Room needs fixtures replaced. Towel holder not in good condition and bath tub spigot needs to be worked on. The door security latch is broken and the mattress is way too soft. Staff was very helpful.
Reviewed on 21 Apr 2026
InterContinental Houston by IHG
Beautiful property
Reviewed on 22 Apr 2026
The Westin Houston Medical Center/Museum District
The staff was very delightful, room was exactly what I expected plus more. Clean room, bed was so comfortable. Valet top tier!
Reviewed on 17 Apr 2026
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Parking was fine. Room temperature was easily controlled. The room we checked in for had a problem, but the front desk took care of giving us another room very easily and quickly. No complaints from us.
Reviewed on 22 Apr 2026
Houston Marriott Medical Center/Museum District
The hotel is very well-maintained and our room was clean and comfortable. The valet service for the shuttle was excellent with everyone involved giving special consideration to the passengers, most of whom were in Houston for medical reasons and were being transported to the various hospitals within ...
Reviewed on 13 Apr 2026
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Other neighbourhoods around South Central Houston
Greater Third Ward
If you're spending time in Greater Third Ward, check out sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Midtown is well liked for its restaurants and live music. If you're hoping to get in some sightseeing, Continental Club and Houston Fire Museum are top spots, and you can jump on the metro at McGowen Station or Ensemble/HCC Station to get around.
East Downtown Houston
The restaurants and live music are just a few things visitors like about East Downtown Houston. Shell Energy Stadium and Giant Beatles Statues are worthwhile spots to check out, and you can hop on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the larger area.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.
