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20 Apr - 21 Apr
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21 Apr - 22 Apr
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24 Apr - 26 Apr
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Our top choices for South Central Houston hotels

Laptop workspace, blackout curtains, soundproofing, iron/ironing board

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
8.6 out of 10, Excellent, (118 reviews)
"Good hotel. great location. "
United States
Porfirio
The price is ₹8,363
₹9,785 total
includes taxes & fees
22 Apr - 23 Apr
Downtowner Inns - Houston Downtown
Premium bedding, pillow-top beds, minibar, in-room safe

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,002 reviews)
"Awesome hotel. "
United States
john
The price is ₹18,940
₹26,378 total
includes taxes & fees
26 Apr - 27 Apr
Hotel Zaza Houston Museum District
Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,145 reviews)
"Great central location within the walking distance to many places. "
United States
Kasey
The price is ₹13,436
₹16,723 total
includes taxes & fees
17 May - 18 May
The Westin Houston Medical Center/Museum District
Exterior

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,003 reviews)
"Wonderful location to events at NRG. Very clean, friendly staff and great bar area. "
United States
Staci
The price is ₹15,704
₹20,233 total
includes taxes & fees
17 May - 18 May
InterContinental Houston by IHG
Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (1,882 reviews)
"Very clean property, staff was helpful"
United States
Elton
The price is ₹9,236
₹10,914 total
includes taxes & fees
26 Apr - 27 Apr
Hilton Houston Plaza/Medical Center
Reception

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,005 reviews)
"Clean, convenient, quiet and very friendly staff. Would stay here again."
United States
Ruben
The price is ₹9,200
₹10,764 total
includes taxes & fees
21 Apr - 22 Apr
Americas Best Value Inn Medical Center Downtown
American cuisine

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was great "
United States
Casey
The price is ₹17,563
₹23,586 total
includes taxes & fees
25 Apr - 26 Apr
Houston Marriott Medical Center/Museum District
Exterior detail

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (10 reviews)
"Jerrick (front desk) was super friendly and helpful, and the room and amenities were great."
United States
Cade
The price is ₹14,134
₹19,255 total
includes taxes & fees
26 Apr - 27 Apr
Sentral Forme Houston
Exterior

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (568 reviews)
"Loved the area, the staff was super friendly and accomodating. "
United States
Silvia Alejandra
The price is ₹16,634
₹19,461 total
includes taxes & fees
23 Apr - 24 Apr
La Maison in Midtown an urban B&B
House | 4 bedrooms, desk, iron/ironing board, Internet

Paradise Palace Best Rooftop in HTX w Hot Tub

Paradise Palace Best Rooftop in HTX w Hot Tub
3.0 star property
South Central Houston
The price is ₹28,801
₹65,770 total
includes taxes & fees
4 May - 5 May
Paradise Palace Best Rooftop in HTX w Hot Tub
Breakfast and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (562 reviews)
"Breakfast was pricey"
United States
Thomas
The price is ₹9,731
₹11,385 total
includes taxes & fees
25 Apr - 26 Apr
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (211 reviews)
"Thoroughly enjoyed our stay. Nick, the property manager is very nice and thoughtful. The bed was so comfortable and the best part for me was the incredibly private and quiet spaces. "
United States
Misty
The price is ₹19,235
₹23,899 total
includes taxes & fees
22 Apr - 23 Apr
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Reception

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (69 reviews)
"Great location will stay again "
United States
Jason
The price is ₹11,184
₹13,087 total
includes taxes & fees
10 May - 11 May
Wanderstay Boutique Hotel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout curtains, free WiFi

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (235 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is ₹5,436
₹6,361 total
includes taxes & fees
24 Apr - 25 Apr
Southmore Boulevard Motel
Lobby

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (932 reviews)
"Booking was easy, staff was super friendly, and the location was perfect for what I needed! "
United States
Brandon
The price is ₹12,808
₹14,985 total
includes taxes & fees
19 May - 20 May
Hilton University of Houston
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,008 reviews)
"Room was clean and had a very comfortable bed We had a very pleasant stay. We were very comfortable and felt quite safe st this property. "
United States
Nilda
The price is ₹6,857
₹8,049 total
includes taxes & fees
23 Apr - 24 Apr
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Breakfast area

Rodeway Inn & Suites Houston near Medical Center

Rodeway Inn & Suites Houston near Medical Center
2.0 star property
South Central Houston
6.0 out of 10, (511 reviews)
"Very dirty place. No TV. Air conditioning did work."
United States
Gabriela
The price is ₹5,435
₹6,359 total
includes taxes & fees
21 Apr - 22 Apr
Rodeway Inn & Suites Houston near Medical Center
Reception

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (1 review)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is ₹5,111
₹6,491 total
includes taxes & fees
21 Apr - 22 Apr
Golden Motel Near Houston Medical Center
Interior

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (198 reviews)
"it was a great experience, staff was kind and helpful. "
United States
James
The price is ₹5,428
₹6,351 total
includes taxes & fees
21 Apr - 22 Apr
Wanderstay Houston Hostel
House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

Posh Dtwn Midtown Home w Stunning Roof-topterrace
3.0 star property
South Central Houston
The price is ₹22,932
₹64,676 total
includes taxes & fees
27 Apr - 28 Apr
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Reception
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
69 reviews
View
Exterior detail
Sentral Forme Houston
4.5 star property
9.2
Wonderful
10 reviews
View
Exterior
InterContinental Houston by IHG
4.0 star property
9.2
Wonderful
1,003 reviews
View
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,145 reviews
View
Premium bedding, pillow-top beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.0
Wonderful
1,002 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

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Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

10/10 Excellent
"Fresh coffee every morning. Room was clean and spacious. A good location to access all of Houston with highway access nearby."
Cynthia 4-night trip
Posted 6 hours ago
Downtowner Inns - Houston Downtown

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Children's Museum of Houston and Houston Natural Science Museum as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1087 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Children's Museum of Houston and Houston Natural Science Museum are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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