What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Children's Museum of Houston and Houston Natural Science Museum as part of your South Central Houston travel plans.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, La Maison in Midtown an urban B&B is the highest ranked property in South Central Houston. This B&B is a short 5-minute walk from Westheimer Road, and it offers free breakfast and free parking. Other top choices in the neighbourhood include Wanderstay Boutique Hotel and The Westin Houston Medical Center/Museum District .

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1070 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Children's Museum of Houston and Houston Natural Science Museum are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

The Best Hotels in South Central Houston, Houston - 2026 Updated Prices

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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

South Central Houston

Jordan

₹10,665 total

includes taxes & fees

4 Apr - 5 Apr

Hilton Houston Plaza/Medical Center

South Central Houston

Diane

₹10,737 total

includes taxes & fees

29 Mar - 30 Mar

DoubleTree by Hilton Houston Medical Center Hotel & Suites

South Central Houston

Judy

₹12,691 total

includes taxes & fees

30 Mar - 31 Mar

Americas Best Value Inn Medical Center Downtown

South Central Houston

Deiedra

₹10,596 total

includes taxes & fees

23 Mar - 24 Mar

Newly Built Modern 3 Bedroom Houston Home

South Central Houston

"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...

robin

₹40,116 total

includes taxes & fees

23 Mar - 24 Mar

Wanderstay Boutique Hotel

South Central Houston

Jason

₹13,640 total

includes taxes & fees

1 Apr - 2 Apr

InterContinental Houston by IHG

South Central Houston

ERIC

₹20,880 total

includes taxes & fees

29 Mar - 30 Mar

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

South Central Houston

Daniella

₹23,527 total

includes taxes & fees

9 Mar - 10 Mar

La Maison in Midtown an urban B&B

South Central Houston

Eugene

₹17,243 total

includes taxes & fees

15 Mar - 16 Mar

Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

South Central Houston

Travis

₹17,455 total

includes taxes & fees

5 Apr - 6 Apr

Houston Marriott Medical Center/Museum District

South Central Houston

Linda

₹22,143 total

includes taxes & fees

3 Apr - 4 Apr

Hilton University of Houston

South Central Houston

Alexandra

₹16,449 total

includes taxes & fees

5 Apr - 6 Apr

Premium bedding, pillow-top beds, minibar, in-room safe

Hotel Zaza Houston Museum District

South Central Houston

Tolbert

Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout curtains, free WiFi

Southmore Boulevard Motel

South Central Houston

Lisa-Maria

₹6,261 total

includes taxes & fees

1 Apr - 2 Apr

Downtown Houston 3BR Bachelorette Escape

South Central Houston

Iesheal

₹41,238 total

includes taxes & fees

17 Mar - 18 Mar

Rodeway Inn & Suites Houston near Medical Center

South Central Houston

AUGUSTIN

₹6,822 total

includes taxes & fees

3 Apr - 4 Apr

Extended Stay America Suites Houston Med Ctr Braeswood Bl

South Central Houston

Tekle

₹8,309 total

includes taxes & fees

29 Mar - 30 Mar

Wanderstay Houston Hostel

South Central Houston

Darius

₹5,903 total

includes taxes & fees

16 Mar - 17 Mar

House | 4 bedrooms, desk, iron/ironing board, Internet

Paradise Palace Best Rooftop in HTX w Hot Tub

South Central Houston

₹75,152 total

includes taxes & fees

18 Mar - 19 Mar

House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

South Central Houston

₹64,988 total

includes taxes & fees

18 Mar - 19 Mar

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Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Discovery Green featuring a high-rise building, a city and modern architecture

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

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The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

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Houston_TexasChildrensHospital_553248635389801905_9

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

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Taken in front of apartments.

#UrbanJungle

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

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Menil Collection featuring interior views

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

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Top South Central Houston Hotel Reviews

InterContinental Houston by IHG

10/10 Excellent

"amenities in room were good. Restaurant on site was very good. Staff were very pleasant"

Houston Marriott Medical Center/Museum District

6/10 Okay

"Old facility; uncomfortable beds and furniture; crispy carpet in room (yuk!); limited onsite dining; noisy area with emergency vehicles coming and going to nearby hospitals, hotel patio area on 4th floor was dirty, not well maintained, and very uninviting. Definitely not worth the per night room rate."

Downtowner Inns - Houston Downtown

10/10 Excellent

"We stayed at this motel for two days and had a really great experience. The person who welcomed us was extremely kind, friendly, and always available to help with anything we needed — that kind of attitude really makes a difference when you’re traveling. The motel is conveniently located close to downtown, which made it easy to get around and explore. The entire property has been fully renovated, and everything feels fresh and well maintained. The bed was very comfortable, perfect after long days out. Breakfast includes waffles, cereals, different types of coffee, juices, and more — simple but complete and definitely better than many other places we’ve stayed at. One of the best motels we’ve visited so far. We would absolutely stay here again."

Search Hotels in South Central Houston, Houston

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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

Hilton Houston Plaza/Medical Center

DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

Newly Built Modern 3 Bedroom Houston Home

Wanderstay Boutique Hotel

InterContinental Houston by IHG

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

La Maison in Midtown an urban B&B

The Westin Houston Medical Center/Museum District

Houston Marriott Medical Center/Museum District

Hilton University of Houston

Hotel Zaza Houston Museum District

Southmore Boulevard Motel

Downtown Houston 3BR Bachelorette Escape

Rodeway Inn & Suites Houston near Medical Center

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Wanderstay Houston Hostel

Paradise Palace Best Rooftop in HTX w Hot Tub

Posh Dtwn Midtown Home w Stunning Roof-topterrace

Where to stay in South Central Houston

Downtown Houston

The Galleria

Texas Medical Center

Houston Central Business District

Montrose

Top South Central Houston Hotel Reviews

InterContinental Houston by IHG

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