Sant' Ambrogio Travel Guide
Florence
Visit Sant' Ambrogio
Popular places to visit
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Piazza del Duomo
The beating heart of Florence is the perfect place to chill out, surrounded by some of the city’s most breathtaking architectural treasures.
Pitti Palace
Head to the south bank of the Arno River to immerse yourself in some of the finest art galleries in Florence.
Top hotels in Sant' Ambrogio
Hotel Bodoni
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Reviewed on 17 Apr 2026
Hotel Bavaria
Excellent location near the Duomo.
Reviewed on 17 Apr 2026
Hotel Regency
The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff.
Reviewed on 12 Apr 2026
Residenza D'Epoca Sant'Egidio
Broken glass left on the floor, I was bleeding out, we tried to contact staff and they were dismissive. There was a constant rattling and banging noise coming from somewhere which made feel very scary and annoying to sleep.
Reviewed on 15 Apr 2026
Villa Tortorelli
Beautiful property!! Easy checkin and the ability to store luggage before and after checkin/out. Staff was so kind and helpful. Love the location, 15 minute walk from the city center. Rooms were clean and beautiful. Very much enjoyed our stay.
Reviewed on 16 Apr 2026
B&B di Piazza del Duomo
Very close to the Duomo as it was in sight! Close to shops, restaurants and cafés. Room was comfortable and exactly as described. Air conditioning worked and was welcome. Room was clean, beds comfortable and bathroom clean.
Reviewed on 17 Apr 2026
Other neighbourhoods around Sant' Ambrogio
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santissima Annunziata
Santissima Annunziata is known for its colourful gardens, and you can plan a trip to Piazza Massimo D'Azeglio and Santissima Annunziata Square while you're in town.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza di Santa Maria Novella while you're exploring the neighbourhood.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
San Niccolò
If you're spending some time in San Niccolò, Arno River and Piazzale Michelangelo are top sights worth seeing.
