Visit Sant' Ambrogio
Popular places to visit
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Piazza del Duomo
The beating heart of Florence is the perfect place to chill out, surrounded by some of the city’s most breathtaking architectural treasures.
Pitti Palace
Head to the south bank of the Arno River to immerse yourself in some of the finest art galleries in Florence.
Top hotels in Sant' Ambrogio
Hotel Bodoni
Clean room, convenient location, lovely terrace
Reviewed on 10 Nov 2025
Hotel Bavaria
Nicest hotel staff and super convenient location. Would stay again if visiting Florence.
Reviewed on 5 Nov 2025
Hotel Cardinal Of Florence
The location is excelent. Very convinience.
Reviewed on 27 Sept 2025
Residenza D'Epoca Sant'Egidio
This is an excellent choice for location, good basic facilities in a grand historic building with tons of character.
Reviewed on 14 Nov 2025
Hotel Regency
Amazing stay as always. Beautiful hotel but the staff make it great. Feels like a home away from home. Perfect location that is easily walkable everywhere in the historic center.
Reviewed on 17 Nov 2025
B&B di Piazza del Duomo
The hotel has excellent location in the very heart of the city. The room was nice and clean. The stuff was always ready to help if you have any questions.
Reviewed on 29 Nov 2025
Other neighbourhoods around Sant' Ambrogio
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Via de' Calzaiuoli and Piazza della Repubblica are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santissima Annunziata
Santissima Annunziata is known for its colourful gardens, and you can plan a trip to Piazza Massimo D'Azeglio and Santissima Annunziata Square while you're in town.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
San Niccolò
If you're spending some time in San Niccolò, Arno River and Piazzale Michelangelo are top sights worth seeing.
