Visit Sant' Ambrogio
Popular places to visit
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the acclaimed art galleries in this vibrant area.
Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Ponte Vecchio
The shop-lined Ponte Vecchio over the River Arno is one of Florence’s most familiar and most romantic landmarks.
Uffizi Gallery
A visit to Florence’s famous art gallery will bring you face to face with some of the world’s best-loved masterpieces.
Pitti Palace
Head to the south bank of the Arno River to immerse yourself in some of the finest art galleries in Florence.
Piazza del Duomo
The beating heart of Florence is the perfect place to chill out, surrounded by some of the city’s most breathtaking architectural treasures.
Top hotels in Sant' Ambrogio
Hotel Regency
I've stayed here multiple times and absolutely love the staff. They are BEYOND wonderful. They are Four Seasons/ Ritz Carlton tier!!! It's the perfect personalised luxury hotel. I'd live here!!!!
Reviewed on 26 Dec 2025
Hotel Cardinal Of Florence
I can not say enough good things about this hotel and our 16-day stay! Giuseppe and the other front desk staff went out of their way to help, provide recommendation and help when my husband got sick. Thank you so much! Many folks have commented about the stairs. But the climb (there are 67 to be ...
Reviewed on 2 Jan 2026
Hotel Bodoni
Good value for your money, close to Firenze duome
Reviewed on 12 Jan 2026
Hotel Bavaria
Sensational location, huge room. Very old fashioned but comfortable.
Reviewed on 15 Jan 2026
Residenza D'Epoca Sant'Egidio
WOW! What an experience to stay in this property. I could imagine living in this period as I made my way to and from the room every day. The folks helping with check in and out were very friendly and responsive. The room was clean and had plenty of comforts when needed. Great location with a minuet ...
Reviewed on 4 Jan 2026
Residenza d'Epoca Borgo Albizi
Conveniently located about 10 mins from the Duomo and on a street with great access to shopping and restaurants. The best shower I have experienced compared to my last 2 accommodations on the same trip. The toilet is heated, the hot water is immediate, powerful and continuous. Only minor complaint ...
Reviewed on 19 Dec 2025
Other neighbourhoods around Sant' Ambrogio
Santa Croce
Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santissima Annunziata
Santissima Annunziata is known for its colourful gardens, and you can plan a trip to Florence Botanical Gardens and Santissima Annunziata Square while you're in town.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza di Santa Maria Novella or Via de' Calzaiuoli while you're exploring the neighbourhood.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
San Niccolò
If you're spending some time in San Niccolò, Arno River and Piazzale Michelangelo are top sights worth seeing.
