What's it like in Downtown South San Francisco?

You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.

What's a favourite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favourite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N .

How many hotels should I expect to find in the Downtown South San Francisco area?

When you want to put your feet up after a day of exploring the sights in South San Francisco, you can choose from 14 Expedia hotels and other accommodation options in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.

What can I see and do in this South San Francisco neighbourhood?

See's Candies, Cinemark Century at Tanforan and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.

The Best Hotels in Downtown South San Francisco, San Francisco - 2026 Updated Prices

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco

manuel

₹10,896 total

includes taxes & fees

25 Jan - 26 Jan

Airport Inn

Downtown South San Francisco

Christopher

₹10,231 total

includes taxes & fees

23 Jan - 24 Jan

Premium bedding, pillow-top beds, in-room safe, desk

Inn By The SFO

Downtown South San Francisco

Gabriel

Deluxe Room | 1 bedroom, individually decorated, individually furnished, desk

Miller Apartments

Downtown South San Francisco

Kasey

₹14,962 total

includes taxes & fees

24 Jan - 25 Jan

Hotel Riu Plaza Fisherman's Wharf

16.7 km from Downtown South San Francisco

Gary

₹16,585 total

includes taxes & fees

25 Jan - 26 Jan

Hotel Aura SFO

4.4 km from Downtown South San Francisco

Victor

₹9,834 total

includes taxes & fees

25 Jan - 26 Jan

Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Hotel Caza Fisherman's Wharf

16.7 km from Downtown South San Francisco

Harold Franklin

₹18,379 total

includes taxes & fees

22 Feb - 23 Feb

Hotel Zoe Fisherman's Wharf

16.6 km from Downtown South San Francisco

Sergio

₹15,011 total

includes taxes & fees

9 Feb - 10 Feb

Breakfast, lunch, dinner served; local cuisine

DoubleTree by Hilton San Francisco Airport

9.3 km from Downtown South San Francisco

Mary Ann

₹10,003 total

includes taxes & fees

30 Jan - 31 Jan

The Westin San Francisco Airport

6.9 km from Downtown South San Francisco

Risa

₹14,414 total

includes taxes & fees

25 Jan - 26 Jan

Hilton San Francisco Airport Bayfront

9.9 km from Downtown South San Francisco

Daniel

₹10,941 total

includes taxes & fees

31 Jan - 1 Feb

The Dylan at SFO

7.1 km from Downtown South San Francisco

Alan

₹11,928 total

includes taxes & fees

23 Jan - 24 Jan

Hilton San Francisco Financial District

15.4 km from Downtown South San Francisco

Christine

₹11,560 total

includes taxes & fees

15 Feb - 16 Feb

YOTEL San Francisco

13.8 km from Downtown South San Francisco

Sherretha

₹11,951 total

includes taxes & fees

27 Jan - 28 Jan

Hotel Zephyr San Francisco

16.8 km from Downtown South San Francisco

Deborah

₹17,286 total

includes taxes & fees

28 Jan - 29 Jan

Aloft San Francisco Airport

6.9 km from Downtown South San Francisco

Jon

₹12,152 total

includes taxes & fees

14 Feb - 15 Feb

Hotel Aluxor SFO

3.8 km from Downtown South San Francisco

Alondra

₹9,705 total

includes taxes & fees

15 Feb - 16 Feb

Handlery Union Square Hotel

14.5 km from Downtown South San Francisco

Laura

₹61,440 total

includes taxes & fees

5 Feb - 6 Feb

Club Quarters Hotel in San Francisco

15.4 km from Downtown South San Francisco

Natthaya

₹12,731 total

includes taxes & fees

15 Feb - 16 Feb

Hypo-allergenic bedding, in-room safe, desk, laptop workspace

Holiday Inn Golden Gateway by IHG

14.8 km from Downtown South San Francisco

Carlos Emiro

₹12,844 total

includes taxes & fees

25 Jan - 26 Jan

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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Union Square

One of the biggest and most popular shopping plazas across the United States.

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Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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Fisherman's Wharf

A historic neighbourhood by the waterfront, and a great place to eat out and enjoy the busy surroundings.

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South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

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