A bench, a bicycle, and a lake surrounded by trees.

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Check availability on Upstate South Carolina 4 Star Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Upstate South Carolina 4-star hotels

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (570 reviews)
"Wonderful"
United States
colleen
The price is ₹33,215
₹37,633 total
includes taxes & fees
23 Nov - 24 Nov
Grand Bohemian Lodge Greenville, Autograph Collection
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

2. Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (881 reviews)
"Beautiful property and very friendly staff! Highly recommend!"
United States
Nicole
The price is ₹15,598
₹20,804 total
includes taxes & fees
3 Dec - 4 Dec
Hotel Hartness
A hotel facade with arched windows, a fountain, and a sign for "The Westin."

3. The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1,001 reviews)
"This was our first stay and we were very impressed. Great location and helpful staff. Very nice room and comfy beds. Good restaurants within walking distance. Highly recommend."
United States
Mary C
The price is ₹15,089
₹17,381 total
includes taxes & fees
22 Nov - 23 Nov
The Westin Poinsett Greenville
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

4. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (935 reviews)
"Great location, convenient!"
United States
Michelle
The price is ₹8,973
₹9,871 total
includes taxes & fees
1 Dec - 2 Dec
Mint House Greenville Downtown by Kasa
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

5. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (657 reviews)
"Great place."
United States
John
The price is ₹14,434
₹16,022 total
includes taxes & fees
15 Nov - 16 Nov
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

6. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (906 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is ₹19,834
₹22,016 total
includes taxes & fees
4 Nov - 5 Nov
The Shepherd Hotel Downtown Clemson
A bar area with multiple hanging decorative lights, a counter with bar stools, and a seating area with chairs.

7. Greenville Marriott

Greenville Marriott
4.0 star property
Greenville
8.6 out of 10, Excellent, (714 reviews)
"We had a great stay! Rooms were very clean and beds very comfortable!!"
United States
John
The price is ₹10,819
₹12,257 total
includes taxes & fees
29 Nov - 30 Nov
Greenville Marriott
Lobby

8. Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport
4.0 star property
Greer
9.4 out of 10, Exceptional, (33 reviews)
"Great stay"
United States
Brittany
The price is ₹11,595
₹13,137 total
includes taxes & fees
19 Nov - 20 Nov
Doubletree By Hilton Greenville Airport
A modern building with outdoor seating and a garden.

9. The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (24 reviews)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is ₹20,880
₹30,797 total
includes taxes & fees
29 Nov - 30 Nov
The Station by Compo Hotels
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.

10. Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (37 reviews)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is ₹39,763
₹43,739 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Domestique
A spacious living room with a stone fireplace, wooden beams, and a chandelier.

11. Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek
4.0 star property
Greer
9.2 out of 10, Wonderful, (5 reviews)
"The apartment was clean. Excellent value for stay. Amenities were great. Will book again!"
United States
Amanda
Landing Apartments Greer - Sugar Creek
A bedroom with a bed, a chair, and a potted aloe plant on a table.

12. Landing Furnished Apartments - Spartanburg, SC

Landing Furnished Apartments - Spartanburg, SC
4.0 star property
Spartanburg
Landing Furnished Apartments - Spartanburg, SC
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.

13. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"Property is in a great community, and it was very clean and beautifully decorated."
United States
Anonymous traveller
Designer Retreat w/ Pool, Golf + Beach Access!
An indoor swimming pool with clear lanes, a covered roof, and a bench area.

14. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
4.0 star property
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A sandy beach with a calm lake surrounded by trees.

15. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
4.0 star property
Salem
10.0 out of 10, Exceptional, (2 reviews)
"Wow!! Absolutely beautiful property. Recent remodel with beautiful and very tasteful design. Amazingly clean, organized and tidy. We are from Denver and did not have exposure to Lake Keowee. The lake was beautiful with great walking trails on the property. Special and spectacular spot! We will definitely go back. This is a gated community. Super comfortable king beds and nice linens."
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!
A swimming pool with a view of the lake and docked boats.

16. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
4.0 star property
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.

17. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
4.0 star property
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.

18. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
4.0 star property
Salem
Views, Pools & Marina: Lake Keowee Condo!
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.

19. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
4.0 star property
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
Interior

20. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
4.0 star property
Salem
10.0 out of 10, Exceptional, (1 review)
"This is a beautiful property in a beautiful location. Amenities are excellent. Beds are comfortable and there are plenty of towels and extra blankets. Kitchen is well stocked either basics for cooking. It took us about 25 minutes to get to Clemson- where we were visiting- but it is well worth the drive!"
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina
A multi-tiered waterfall cascading over rocks in a forested area.
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

Take Your Pick of 4 Star Hotels in Upstate South Carolina

The get-go of any holiday starts with choosing a great spot. Upstate South Carolina has been a popular destination with guests because it offers so much to do and see. But, "location, location, location" applies to more than just what city where your plane lands. Now that you have a feel for the town, it's time you to get to know your new digs.

Accommodations as Picturesque as Upstate South Carolina

Search Expedia.com.sg for the right 4 Star Upstate South Carolina Hotel to suit your fancy. Plenty of these people wrote tips to help you select the accommodation that is the right fit for your holiday.You'll be more than glad to get back to your resort every night. Upstate South Carolina has dozens of good options in the 4-star hotel range that create the ideal getaway.

A stay at one of these lodgings ensure that whether you are just relaxing after a day of checking out Upstate South Carolina or you are ready to lie down for the night, you'll be as comfortable as possible. You won't go without a thing during your stay at one of these accommodations. Visitors have consistently given them high marks for their attentive service. It's no surprise that loads of guests recommend it.

Reserve a 4-Star Hotel in Upstate South Carolina Today!

Your trip to Upstate South Carolina should be one that you'll reminisce over for years to come, and booking a 4-star hotel will help create memories that are incredible. Make sure to make a reservation soon. With so few hotels, and plenty of people desiring to vacation in Upstate South Carolina, you may miss out on your perfect hotel.

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