Compare and book 3 Star hotels in Southeast Missouri, Missouri
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Top Southeast Missouri 3 Star Hotels

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO

Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
Explore similar 4-star hotels

Urban Lofts
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Find out more about Southeast Missouri
Find out more about Southeast Missouri
Find Your Ideal 3 Star Hotel in Southeast Missouri
There's a reason the top 3-star hotels in Southeast Missouri, Missouri, United States of America are so incredibly popular: They combine comforting amenities and just-for-you service with some of the best rates and discounts the area has to offer. When you book a stay at a three star hotel in Southeast Missouri, you'll get affordable rates at these mid-range properties. Check through our listings and you'll find some hotels may even give you access to perfect little perks like on-site restaurants and cocktail bars, well-appointed fitness centres, and spacious rooms.
Search for a cheap deal on a 3 star hotel in Southeast Missouri for the most elegant experience, or grab a low rate on one of the cheap 3 star hotels in Southeast Missouri near the local attractions, if you want something a touch more unassuming. Whatever your travelling style, make sure to use the search tools at Expedia to track down prices, read more about amenities, and score a few local discounts.
From business trips to family getaways, the Southeast Missouri 3 star hotels offer a fantastic economical yet comfortable stay for any type of holiday.
Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
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Explore a world of travel with Expedia
Hotels in Southeast Missouri by Star Rating
Areas of Southeast Missouri
Accommodation near Southeast Missouri attractions
- Hotels near Mark Twain National Forest
- Hotels near Johnson's Shut-ins State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Hotels near Echo Bluff State Park
- Hotels near Isle Casino Cape Girardeau
- Hotels near Current River State Park
- Hotels near Sainte Genevieve Winery
Choose Your Southeast Missouri Hotel Style
- Business Hotels in Southeast Missouri
- Casino Hotels in Southeast Missouri
- Cheap Hotels in Southeast Missouri
- Family-Friendly Hotels in Southeast Missouri
- Golf Hotels in Southeast Missouri
- Historic Hotels in Southeast Missouri
- Hotels Suites in Southeast Missouri
- Hotels near Museums in Southeast Missouri
- Hotels with Air Conditioning in Southeast Missouri
- Hotels with Breakfast in Southeast Missouri
- Hotels with Connecting Rooms in Southeast Missouri
- Hotels with Entertainment in Southeast Missouri
- Hotels with Gym in Southeast Missouri
- Hotels with Hot Tubs in Southeast Missouri
- Hotels with Indoor Pools in Southeast Missouri
- Hotels with Laundry Service in Southeast Missouri
- Hotels with Parking in Southeast Missouri
- Hotels with Parking in Southeast Missouri
- Hotels with Restaurant in Southeast Missouri
- Hotels with Swimming Pool in Southeast Missouri
- Hotels with Views in Southeast Missouri
- Hotels with Wifi in Southeast Missouri
- Hotels with a Bar in Southeast Missouri
- Hotels with smoking rooms in Southeast Missouri
- Luxury Hotels in Southeast Missouri
- Pet-Friendly Hotels in Southeast Missouri
- Romantic Hotels in Southeast Missouri
- Shopping Hotels in Southeast Missouri
- Spa Hotels in Southeast Missouri
- Sports Hotels in Southeast Missouri
- Wedding Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
Explore more hotels
- Drury Inn & Suites Sikeston, MO
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Quality Inn
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Cape Girardeau West
- Courtyard by Marriott Cape Girardeau Downtown
- Postcard Cabins St. Francois
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Drury Inn & Suites Jackson MO
- Drury Inn & Suites Poplar Bluff
- Super 8 by Wyndham Perryville
- Holiday Inn Express & Suites Perryville by IHG
- Super 8 by Wyndham Poplar Bluff Missouri
- Super 8 by Wyndham Farmington
- Pear Tree Inn Sikeston
- Drury Inn & Suites Hayti Caruthersville
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