Photo by Catherine Edejer-McCormick

Search Hotels in Downtown South San Francisco, San Francisco

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Property class
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top Trending Hotels Near Downtown South San Francisco, San Francisco

Other neighbourhoods around Downtown South San Francisco

Hotels in top San Francisco neighborhoods Learn more about Downtown South San Francisco
Fisherman\'s Wharf featuring a marina and a city

Fisherman's Wharf

1 out of top 10 points of interest in this area
5/5(4 area reviews)

A historic neighbourhood by the waterfront, and a great place to eat out and enjoy the busy surroundings.

Find hotels in Fisherman's Wharf

Downtown South San Francisco hotels information

Number of reviews
30,053
Accommodation
4,902 hotels
Lowest Price
₹3,687
Highest Price
₹17,178

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun exploring South San Francisco's Downtown South San Francisco neighbourhood.

What's a favourite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favourite options in the area include Airport Inn and Inn By The SFO.

How many hotels should I expect to find in the Downtown South San Francisco area?

Expedia has 43 hotels and other accommodation options in Downtown South San Francisco to choose from, making this an ideal home base for exploring the greater South San Francisco area.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Downtown South San Francisco.

What can I see and do in this South San Francisco neighbourhood?

See's Candies, K1 Speed San Francisco and The Shops at Tanforan are just a few of the places to visit in and around Downtown South San Francisco. San Bruno Point Park and SFO Museum are also worth a visit when you're out sightseeing in South San Francisco.

Downtown South San Francisco Hotel Reviews

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

5/5 Excellent
"Great staff, parking, and nice clean room. Will be coming back!"
A verified traveller stayed at Chancellor Hotel on Union Square
Posted 12 hours ago
Chancellor Hotel on Union Square