Southeast Missouri Pet-friendly Holidays

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Top Pet-friendly Southeast Missouri Hotels

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
  • 3 hours drive from Mark Twain National Forest
Stay at this motel in Poplar Bluff. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their ...
7.8/10 Good! (1,002 reviews)
"Friendly staff. Had everything we needed. No microwave. My husband said mattress wasn’t very comfortable but it didn’t bother me that much. No breakfast."

Reviewed on 25 Jun 2025

Motel 6 Poplar Bluff, MO
Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 out of 5
21958 Hwy 32, Ste Genevieve, MO
  • 4 hours drive from Mark Twain National Forest
Stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (577 reviews)
Gross cleaning service in front of guests at bkfst
"The first morning we ate breakfast (24th) as we were in the breakfast room I witnessed a female cleaning the area. She used a rag to scrub at the floor in front of the coffee machine. Nothing unusual, but I kept watching. She then stood up, rinsed out the rag then immediately started to wipe down ..."

Reviewed on 27 Jun 2025

Microtel Inn & Suites by Wyndham Sainte Genevieve
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3 out of 5
1001 Veterans Blvd, Festus, MO
  • 3 hours drive from Mark Twain National Forest
Stay at this 3-star business-friendly hotel in Festus. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (807 reviews)
Dog friendly.
"Super easy check in. Dog friendly!"

Reviewed on 30 Jun 2025

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.