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Top Luxury Charleston Hotels

The Charleston Place

205 Meeting Street Charleston SC

8 min walk from Medical University of South Carolina

Stay at this luxury hotel in Charleston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the property condition ...

9.6/10 Exceptional! (1,003 reviews)

Great location

Reviewed on 7 May 2026

Market Pavilion Hotel

225 East Bay Street Charleston SC

10 min walk from Medical University of South Carolina

Stay at this luxury hotel in Charleston. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their ...

9.4/10 Exceptional! (1,004 reviews)

Friendly and attentive Beautiful hotel. Close to everything

Reviewed on 4 May 2026

Planters Inn

112 N Market St Charleston SC

9 min walk from Medical University of South Carolina

Stay at this luxury hotel in Charleston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...

9.6/10 Exceptional! (1,013 reviews)

Everything was great

Reviewed on 9 May 2026

See all 5,040 properties in Charleston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.