Southeast Missouri Adventure Holidays 2026

Photo by JG Morris

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Top Adventure Southeast Missouri Hotels

Hampton Inn Farmington

850 Valley Creek Dr Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

Crown Pointe Lodge, BW Signature Collection

4245 Hunt Rd Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this golf hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (664 reviews)

"We booked Crown Point for my father’s Celebration of Life, which was held next door. Many of my family members stayed there. It was a convenient location, the staff was accommodating, and they allowed us to use the lobby space for gathering every night. The only issue was billing/checking out. We ..."

Reviewed on 13 Aug 2026

Echo Bluff State Park

34489 Echo Bluff Dr Eminence MO

43 min drive from Mark Twain National Forest

Stay at this business-friendly hotel in Eminence. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Echo Bluff State Park and Current ...

See all 670 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.