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Top Adventure Southeast Missouri Hotels

Hampton Inn Farmington

850 Valley Creek Dr Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

8.8/10 Excellent! (539 reviews)

Just ok. Trouble getting in internet

Reviewed on 26 Mar 2026

Crown Pointe Lodge, BW Signature Collection

4245 Hunt Rd Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this golf hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (600 reviews)

Overall it was okay, we’ve stayed here for years but it has changed owners and with that different management. Staff takes all the upfront parking including the manager. Parking in the handicap striped space that’s suppose to allow cars with handicap tags the ability to open their doors fully or ...

Reviewed on 25 Mar 2026

Echo Bluff State Park

34489 Echo Bluff Dr Eminence MO

43 min drive from Mark Twain National Forest

Stay at this business-friendly hotel in Eminence. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Echo Bluff State Park and Current ...

9.6/10 Exceptional! (234 reviews)

The lodge was beautiful! Our room was good for our time there. We enjoyed being able to eat at the grille and relax for the weekend!

Reviewed on 22 Mar 2026

See all 630 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.