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Top Adults Only Charleston Hotels

86 Cannon Charleston - Adults Only

86 Cannon Street Charleston SC

5 min walk from Medical University of South Carolina

Stay at this luxury inn in Charleston. Enjoy free breakfast, free Wi-Fi and free bicycles on-site. Popular attractions Charleston City Market and South Carolina ...

The Jasmine House

64 Hassell Street Charleston SC

7 min walk from Medical University of South Carolina

Stay at this guesthouse in Charleston. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ...

9.4/10 Exceptional! (385 reviews)

Our original room we booked had an issue so they changed our room unfortunately but wavered the parking fee. The inn is in a great location within walking distance to king street. The room has a wonderful basket full of goodies and drinks in the mini fridge that was complimentary which was wonderful! ...

Reviewed on 7 May 2026

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

5757 Palm Boulevard Isle of Palms SC

7 min drive from Medical University of South Carolina

Stay at this beach resort in Isle of Palms. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...

8.8/10 Excellent! (1,005 reviews)

Nice property with lots of amenities.

Reviewed on 30 Apr 2026

See all 5,043 properties in Charleston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.