Popular airlines from South Carolina
American Airlines
United
Delta
British Airways
KLM
Air France
Air Canada
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 25% on select hotels after you book a flight*
- Top Flights Destinations
- Flights from Other Cities
- Cheap Flights from Other Airports
- Expedia's Latest Trends
- Flights to Las Vegas
- Flights to New York
- Flights to Orlando
- Flights to Myrtle Beach
- Flights to Chicago
- Flights to San Diego
- Flights to Panama City Beach
- Flights to Destin
- Flights to Ocean City
- Flights to Los Angeles
- Flights to Miami
- Flights to Boston
- Flights to Gulf Shores
- Flights to Nashville
- Flights to Atlantic City
- Flights to Pigeon Forge
- Flights to Virginia Beach
- Flights to Atlanta
- Flights to San Francisco
- Flights to Houston
- Flights from Myrtle Beach
- Flights from Charleston
- Flights from Hilton Head Island
- Flights from North Myrtle Beach
- Flights from Charlotte
- Flights from Savannah
- Flights from Folly Beach
- Flights from Surfside Beach
- Flights from Columbia
- Flights from Kiawah Island
- Flights from Greenville
- Flights from Mount Pleasant
Nearby Airports
- Columbia Metropolitan Airport (CAE)
- Augusta Regional Airport (AGS)
- Florence Regional Airport (FLO)
- Charlotte-Douglas Intl. Airport (CLT)
- Greenville-Spartanburg Intl. Airport (GSP)
- Myrtle Beach Intl. Airport (MYR)
- Hilton Head Island Airport (HHH)
- Savannah - Hilton Head Intl. Airport (SAV)
- Asheville Regional Airport (AVL)
- Grand Strand Airport (CRE)
Expedia's Latest Trends
Flights
*Available to Expedia members.