𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Upstate South Carolina (2026)

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

An indoor swimming pool with lounge chairs and potted plants.

1. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Pedro

₹9,795

₹11,097 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

A modern hotel lobby with a bar area, seating, and a large window providing natural light.

A modern lounge area with comfortable seating, a round table, and a large screen.

2. Courtyard by Marriott Greenville Mauldin

Greenville

Leticia

₹11,358

₹12,494 total

includes taxes & fees

13 Sept - 14 Sept

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A pool area with lounge chairs and a sign for Best Western Plus.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

3. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Sara

₹7,178

₹7,895 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with modern furniture, a chandelier, and potted plants.

A bar with a white countertop, multiple bar stools, and shelves stocked with bottles.

An outdoor seating area with tables and chairs, potted plants, and a modern building facade.

4. Hilton Greenville

Greenville

Edward

₹10,892

₹12,340 total

includes taxes & fees

20 Sept - 21 Sept

A modern building with a glass facade and a brick base, featuring a prominent entrance with a flag.

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern living room with a fireplace, seating area, and a kitchen in the background.

A swimming pool with lounge chairs and a no diving sign.

5. Comfort Suites Greenville Airport

Greenville

Chandler

₹8,894

₹10,077 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel room with a large bed, a separate bathroom with a bathtub, a nightstand, a lamp, and a wall-mounted artwork.

A reception area with two beige armchairs, a glass-top table, and a vibrant geometric wall art.

A Days Inn by Wyndham hotel with a covered entrance, multiple windows, and a parking area with cars.

A spacious dining area with a central table and chairs, a kitchen in the background, and a sign indicating a breakfast area.

6. Days Inn by Wyndham Greenville South/Mauldin

Mauldin

David

₹6,734

₹7,408 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

A hotel lobby with a reception desk, a patterned carpet, and a large abstract wall art piece.

7. Hampton Inn & Suites Greenville Airport, SC

Greenville

Kristina

₹10,007

₹11,338 total

includes taxes & fees

20 Sept - 21 Sept

A modern hotel lobby with a mix of seating areas, including sofas and tables, and a patterned carpet.

A hotel room with a large bed, a TV, a desk, and a view of the city through large windows.

A modern hotel lobby with a reception desk, seating area, and a decorative wall.

8. Hyatt Place Greenville Downtown

Greenville Downtown

Tamara

₹12,900

₹14,616 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with hanging light fixtures and bar seating.

A modern lobby with a curved reception desk, comfortable seating, and a large wall-mounted TV.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

9. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jeffery

₹11,378

₹12,891 total

includes taxes & fees

27 Sept - 28 Sept

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

10. Drury Inn & Suites Greenville

Greenville

Gohan

₹12,884

₹14,173 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel room with a large bed, a desk, and a seating area with chairs and a table.

A hotel room with a large bed, a television on a dresser, a nightstand with a lamp, and a window with curtains.

A hotel pool area with lounge chairs, a flag, and a sunset view.

A cafe with a checkered floor, wooden cabinets, and hanging pendant lights.

11. Hampton Inn Greenville I-385 - Woodruff Rd.

Greenville

Anne

₹9,716

₹11,009 total

includes taxes & fees

21 Sept - 22 Sept

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel lobby with a reception desk, computers, and a seating area.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

12. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

Paul

₹7,862

₹8,907 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio with a modern design, featuring a seating area with sofas and a fire pit, surrounded by plants and under a pergola with hanging lights.

A modern hotel lobby with a central seating area, a long reception desk, and a kitchen area visible to the right.

A bar area with a central island, multiple bar stools, hanging spherical light fixtures, and a stone pillar.

A modern interior with a bar area, seating, and a staircase.

13. SpringHill Suites by Marriott Greenville Downtown

Greenville Downtown

Douglas

₹13,947

₹15,802 total

includes taxes & fees

4 Oct - 5 Oct

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A gym with treadmills, stationary bikes, and exercise balls.

A hotel room with two beds, a desk, a TV, and a patterned carpet.

14. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Simone

₹7,626

₹8,390 total

includes taxes & fees

13 Sept - 14 Sept

An outdoor patio area with seating and tables, covered by a wooden pergola with string lights.

A modern kitchen with a stainless steel refrigerator, microwave, and sink. There are wooden cabinets and a countertop. A small office area with a desk and chair is visible in the background.

A modern hotel with a covered entrance and multiple floors.

A modern hotel lobby with a central seating area, a kitchenette, and a TV screen.

15. Home2 Suites by Hilton Greenville Airport

Greenville

Brian

₹12,444

₹14,100 total

includes taxes & fees

27 Sept - 28 Sept

A modern outdoor seating area with a glass-top coffee table, blue sofas, and orange patterned cushions.

A snack bar with a variety of packaged foods and beverages, a refrigerated display case, and a counter with a sign that reads 'This and that and then some.'

A modern lobby with a reception desk, seating areas, and a large window offering a view.

16. Tru by Hilton Greenville Woodruff Road

Greenville

Sandra

₹8,835

₹10,621 total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with seating areas, a reception desk, and a staircase.

A modern cafe with a central island, seating area, and a wall with circular patterns.

A hotel room with a bed, two bedside tables, a TV, a desk, a chair, and a sofa.

A hotel room with a desk, a television, a sofa, and a small round table.

17. Wingate by Wyndham - Greenville-Airport

Greenville

Victoria

₹7,653

₹8,419 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with a bed, a desk, a chair, a TV, and a bathroom.

A modern kitchen with wooden cabinets, a white microwave, a stainless steel refrigerator, a dishwasher, and a sink.

A modern hotel lobby with a seating area, a flat-screen TV mounted on the wall, and a reception desk.

18. Extended Stay America Premier Suites Greenville Woodruff Rd

Greenville

Debra

₹7,473

₹8,220 total

includes taxes & fees

27 Sept - 28 Sept

A spacious living area with a fireplace, a beige sofa, and a modern chandelier.

An outdoor patio area with a fire feature, wicker furniture, and potted plants.

A modern breakfast bar with wooden stools, a coffee station, and a variety of breakfast items.

A multi-story hotel with a prominent entrance and a landscaped driveway.

19. Hilton Garden Inn Greenville

Greenville

Pedro

₹9,314

₹10,553 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio with wicker furniture, a stone fire pit, and a pergola.

A building entrance with a stone facade, a number '31' above the door, and a modern light fixture above.

A hotel room with a sofa, a desk, a television, a chair, a small cabinet, and a bed.

A compact kitchen with a refrigerator, microwave, coffee maker, and a flat-screen TV.

20. Staybridge Suites Greenville I-85 Woodruff Road by IHG

Greenville

Jonathan

₹15,653

₹17,219 total

includes taxes & fees

13 Sept - 14 Sept

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Holiday Rentals in Upstate South Carolina

Aparthotel

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

stayAPT Suites Greenville-Haywood Mall

Greenville

"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"The unit was very clean, and I stay here whenever I'm in Greenville."

Cabin

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern kitchen with white cabinets, a large TV, wooden flooring, and a dining area with a bench and coffee table.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Aparthotel

A modern building with outdoor seating and a garden.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A row of modern, two-story buildings with a covered patio area.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Aparthotel

A modern living room with a flat-screen TV, a dining area with a round table and chairs, a kitchen with dark cabinets and a refrigerator, and a sofa with a patterned pillow.

A spacious living area with a ceiling fan, a flat-screen TV, and comfortable seating.

An outdoor patio area with wicker furniture, a fireplace, and a ceiling fan.

A pool area with a covered seating area, lounge chairs, and umbrellas.

Landing Apartments - Lyman

Lyman

"Great room that was nice and clean. Smooth check-in."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

A rustic cabin with a porch, wooden steps, and a picnic table.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A two-story house with a front porch, a small garden, and a wooden fence.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

A spacious kitchen with wooden flooring, white cabinets, and a dining area with a table and chairs.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

Cottage

A modern kitchen with white and blue cabinets, stainless steel appliances, and a central island with bar stools.

A spacious living room with a large TV, comfortable seating, and a kitchen area visible through an open archway.

A dining area with a wooden table, chairs, a vase with a plant, and a chandelier.

A dining area with a wooden table, chairs, and a chandelier. There is a view of a kitchen and a balcony with a railing.

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!

Walhalla

"The house was perfect for our group for our golf trip. We had one minor issue and we were able to speak to the host and they had someone to correct it quickly so that it didn’t disrupt our trip in any way. Place was clean, peaceful, with great hosts."

Apartment

A wooden gazebo with a roof, surrounded by trees, overlooking a lake.

A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

A cozy living room with a fireplace, leather armchair, and a large window.

A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.

Designer Retreat w/ Pool, Golf + Beach Access!

Salem

"Property is in a great community, and it was very clean and beautifully decorated."

Cottage

A cozy cabin interior with a dining area, kitchen, and living space.

A cabin with a gravel driveway, a wooden deck, and a view of a lake surrounded by trees.

A cozy wooden cabin bedroom with a bed, dresser, and ceiling fan.

A wooden cabin kitchen with a granite countertop, stainless steel appliances, and a clock on the wall.

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

Seneca

"Beautiful and quaint cabin! Highly recommend, great view of the lake."

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Frankie's Fun Park to Conestee Nature Preserve.

See all hotels in Upstate South Carolina

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"Excellent all the way around."

Hotel Hartness

10/10 Excellent

"The room was immaculate and the staff was very friendly. Such a beautiful property that is nice to explore. Close to other restaurants and store nearby. Would definitely stay again."

Lakeside Lodge Clemson

10/10 Excellent

"Wow! We were very impressed with the suite and felt like it was brand new! I've stayed in some of the nicest hotels and condos in the country and this place is right in that ballpark! We'll stay there again."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"The hotel was extremely clean and the breakfast delicious. Great location."

Hyatt Place Greenville Downtown

8/10 Good

"Price of the parking is too high"

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent

"Clean, comfortable and convenient."

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"Exceptional staff…. Great service on every level!!"

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Absolutely perfect in every way!"

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC

₹6,109

₹6,872 total

13 Sept - 14 Sept

includes taxes & fees

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

₹7,178

₹7,895 total

13 Sept - 14 Sept

includes taxes & fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

₹7,721

₹8,780 total

27 Sept - 28 Sept

includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

₹9,655

₹10,717 total

14 Sept - 15 Sept

includes taxes & fees

8/10 Very good! (1,005 reviews)

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

₹10,072

₹11,180 total

4 Oct - 5 Oct

includes taxes & fees

8.4/10 Very good! (1,004 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

₹10,404

₹12,915 total

13 Sept - 14 Sept

includes taxes & fees

9/10 Wonderful! (1,002 reviews)

Hotels in Upstate South Carolina with star rating

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Upstate South Carolina Hotels from ₹6,872

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Embassy Suites Greenville Golf Resort & Conference Center

2. Courtyard by Marriott Greenville Mauldin

3. Best Western Plus Greenville I-385 Inn & Suites

4. Hilton Greenville

5. Comfort Suites Greenville Airport

6. Days Inn by Wyndham Greenville South/Mauldin

7. Hampton Inn & Suites Greenville Airport, SC

8. Hyatt Place Greenville Downtown

9. DoubleTree by Hilton Greenville Woodruff Road

10. Drury Inn & Suites Greenville

11. Hampton Inn Greenville I-385 - Woodruff Rd.

12. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

13. SpringHill Suites by Marriott Greenville Downtown

14. Fairfield Inn & Suites by Marriott Greenville Simpsonville

15. Home2 Suites by Hilton Greenville Airport

16. Tru by Hilton Greenville Woodruff Road

17. Wingate by Wyndham - Greenville-Airport

18. Extended Stay America Premier Suites Greenville Woodruff Rd

19. Hilton Garden Inn Greenville

20. Staybridge Suites Greenville I-85 Woodruff Road by IHG

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

Carolina Camp Cedar

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

The Station by Compo Hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Landing Apartments - Lyman

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Greer Guest House < 1 Mi to Park & Downtown Area!

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!

Designer Retreat w/ Pool, Golf + Beach Access!

Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Bon Secours Wellness Arena

Greenville Convention Center

Memorial Stadium

BMW Performance Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Hotel Hartness

Lakeside Lodge Clemson

Comfort Inn & Suites Clemson - University Area

Hyatt Place Greenville Downtown

Embassy Suites Greenville Golf Resort & Conference Center

Grand Bohemian Lodge Greenville, Autograph Collection

The Shepherd Hotel Downtown Clemson

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star rating

Explore a world of travel with Expedia

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