A cityscape with modern skyscrapers, a Ferris wheel, and a clock tower.

Search Adults Only Resorts & Hotels in Southwest Houston

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Houston Adults Only Resorts & Hotels

Our top choices for Southwest Houston adults-only hotels

A rooftop terrace with outdoor seating and a city skyline view at sunset.

1. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,284 reviews)
"Good hotel. Clean and nice staff."
United States
Ariane
The price is ₹10,605
₹13,200 total
includes taxes & fees
21 Nov - 22 Nov
The Westin Houston Medical Center/Museum District
An outdoor patio area with round wooden tables and wicker chairs, a pool, and a covered seating area.

2. Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,000 reviews)
"Will stay again , highly recommend!"
United States
Shatara
The price is ₹9,911
₹11,596 total
includes taxes & fees
26 Nov - 27 Nov
Hilton Garden Inn Houston Medical Center, TX
A multi-story hotel with a modern design, featuring a prominent "HOME" sign, a covered entrance, and a landscaped area with plants.

3. Home2 Suites by Hilton at the Galleria

Home2 Suites by Hilton at the Galleria
3.0 star property
Greater Uptown
9.0 out of 10, Wonderful, (1,101 reviews)
"Great place to stay."
United States
Jeffrey
The price is ₹9,948
₹11,639 total
includes taxes & fees
19 Nov - 20 Nov
Home2 Suites by Hilton at the Galleria
A modern hotel with a prominent 'DoubleTree by Hilton' sign, surrounded by well-maintained greenery and a busy road with traffic.

4. DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
Greenway Plaza-Upper Kirby
8.4 out of 10, Very good, (1,981 reviews)
"Was clean and staff was very friendly"
United States
Scott
The price is ₹7,884
₹9,225 total
includes taxes & fees
26 Nov - 27 Nov
DoubleTree by Hilton Hotel Houston - Greenway Plaza
A modern interior with a sectional sofa, two yellow armchairs, a patterned rug, and a large window with a view.

5. Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (2,739 reviews)
"Great place to stay"
United States
Joel
The price is ₹11,660
₹13,714 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt Place Houston Medical Center
A spacious lobby with a high ceiling, a mezzanine level, and a variety of seating options including sofas and armchairs.

6. Drury Inn & Suites Houston Near the Galleria

Drury Inn & Suites Houston Near the Galleria
3.0 star property
The Galleria
9.4 out of 10, Exceptional, (1,588 reviews)
"Comfortable stay, good breakfast."
United States
Pamela
The price is ₹10,774
₹12,605 total
includes taxes & fees
30 Nov - 1 Dec
Drury Inn & Suites Houston Near the Galleria
A modern hallway with marble flooring, a central bench, two blue chairs, and a large chandelier.

7. The Chifley Houston, Tapestry Collection by Hilton

The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
The Galleria
9.2 out of 10, Wonderful, (1,436 reviews)
"Great stay"
United States
Ronda
The price is ₹10,679
₹12,495 total
includes taxes & fees
26 Nov - 27 Nov
The Chifley Houston, Tapestry Collection by Hilton
A rooftop pool area with a covered seating area, a pool with a metal railing, and a cityscape view in the background.

8. Holiday Inn Express Houston - Galleria Area by IHG

Holiday Inn Express Houston - Galleria Area by IHG
2.5 star property
The Galleria
9.4 out of 10, Exceptional, (1,034 reviews)
"Breakfast was wonderful. Very convenient locatrion."
United States
Patrick
The price is ₹11,473
₹13,424 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express Houston - Galleria Area by IHG
A modern interior with a sectional sofa, two yellow armchairs, a patterned rug, and a large window with a view.

9. Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,260 reviews)
"Clean rooms, helpful staff, and great breakfast."
United States
Nikki
The price is ₹11,660
₹13,714 total
includes taxes & fees
26 Nov - 27 Nov
Hyatt House Houston Medical Center
A modern hotel with a covered entrance, multiple floors, and a Marriott logo.

10. Springhill Suites Houston Westchase

Springhill Suites Houston Westchase
3.0 star property
Alief
8.8 out of 10, Excellent, (980 reviews)
"Clean and great breakfast."
United States
Richard
The price is ₹7,956
₹9,309 total
includes taxes & fees
3 Dec - 4 Dec
Springhill Suites Houston Westchase
A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.

11. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,785 reviews)
"Great hotel definitely would stay again."
United States
Michael
The price is ₹13,804
₹16,203 total
includes taxes & fees
22 Nov - 23 Nov
Blossom Hotel Houston, Curio Collection by Hilton
An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

12. Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (764 reviews)
"This room was spacious and had more amenities than a normal in a double queen room. We enjoyed our stay and will come here again!"
United States
Colleen
The price is ₹11,866
₹13,883 total
includes taxes & fees
23 Nov - 24 Nov
Home2 Suites by Hilton Houston Medical Center, TX
A modern hotel interior with a central spiral staircase, large glass windows, and a buffet area with various food items.

13. The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.8 out of 10, Excellent, (2,451 reviews)
"Great place to stay Would definitely come back"
United States
Bruce
The price is ₹11,149
₹13,045 total
includes taxes & fees
26 Nov - 27 Nov
The Royal Sonesta Houston Galleria
A modern hotel lobby with a wooden reception desk, comfortable seating, and a large decorative wall piece.

14. Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria
3.0 star property
Greater Uptown
8.8 out of 10, Excellent, (1,688 reviews)
"Great place to stay"
Australia
Katrina
The price is ₹10,672
₹12,548 total
includes taxes & fees
25 Nov - 26 Nov
Hyatt Place Houston/Galleria
A modern hotel building with a prominent entrance, large windows, and a visible name sign.

15. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay!"
United States
Luke
The price is ₹14,294
₹18,605 total
includes taxes & fees
22 Nov - 23 Nov
InterContinental Houston by IHG
A spacious lobby with high ceilings, wooden columns, hanging pendant lights, and potted plants.

16. Hilton Garden Inn Houston/Galleria Area

Hilton Garden Inn Houston/Galleria Area
3.0 star property
The Galleria
8.8 out of 10, Excellent, (1,004 reviews)
"We really enjoyed our 1 night stay. Staff was friendly and helpful and the property was clean and well maintained"
United States
Trushay
The price is ₹9,079
₹10,688 total
includes taxes & fees
26 Nov - 27 Nov
Hilton Garden Inn Houston/Galleria Area
A high-rise hotel with a modern design, featuring a prominent curved corner and a sign reading "DOWNTREE SUITES."

17. DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
Greater Uptown
8.4 out of 10, Very good, (4,716 reviews)
"Great stay"
United States
Hernando
The price is ₹10,679
₹12,583 total
includes taxes & fees
26 Nov - 27 Nov
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
A spacious lobby with a reception desk, two sofas, a coffee station, and large windows providing natural light.

18. Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.8 out of 10, Excellent, (1,012 reviews)
"Great location."
United States
Sandra P
The price is ₹8,535
₹9,986 total
includes taxes & fees
6 Dec - 7 Dec
Comfort Suites Houston near Medical Center- NRG Stadium
A modern hotel lobby with a reception desk, seating area, and a large digital display.

19. Champions Club and Hotel, Houston Westchase

Champions Club and Hotel, Houston Westchase
3.0 star property
Alief
8.8 out of 10, Excellent, (665 reviews)
"Good place to stay"
United States
Minh
The price is ₹7,685
₹8,992 total
includes taxes & fees
14 Dec - 15 Dec
Champions Club and Hotel, Houston Westchase
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southwest Houston Hotel Reviews

Explore a world of travel with Expedia