Search Spa Hotels in Southern Indiana

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Nov - 9 Nov
Tomorrow
9 Nov - 10 Nov
Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Our top choices for Southern Indiana hotels with a spa

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

1. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (2,223 reviews)
  • cleanliness
    Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
The price is ₹19,083
₹22,453 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A treatment room with a massage table, a desk with a computer, and a large mirror.

2. Belterra Casino Resort

Belterra Casino Resort
3.5 star property
Florence
8.6 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
The price is ₹10,495
₹12,910 total
includes taxes & fees
24 Nov - 25 Nov
Belterra Casino Resort
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

3. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness centre in city centre Louisville.
The price is ₹14,288
₹17,281 total
includes taxes & fees
29 Nov - 30 Nov
21c Museum Hotel Louisville
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

4. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,475 reviews)
  • cleanliness
    Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
The price is ₹12,783
₹15,041 total
includes taxes & fees
22 Nov - 23 Nov
Galt House Hotel Trademark Collection by Wyndham
A restaurant with round tables, chairs, chandeliers, and a bar area.

5. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very good, (1,005 reviews)
  • cleanliness
    Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
The price is ₹5,684
₹8,187 total
includes taxes & fees
7 Dec - 8 Dec
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
2.5 star property
Seymour
7.0 out of 10, Good, (657 reviews)
  • cleanliness
    Revitalise your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness centre.
The price is ₹7,583
₹8,492 total
includes taxes & fees
7 Dec - 8 Dec
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
3.5 star property
La Grange
10.0 out of 10, Exceptional, (52 reviews)
  • cleanliness
    Relax in a cosy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
The price is ₹31,650
₹34,891 total
includes taxes & fees
16 Nov - 17 Nov
Pillow and Paddock B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included

Top Southern Indiana Hotel Reviews

A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
Pillow and Paddock B&B

Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange

10/10 Excellent

A beautiful tranquil friendly B&B that has the most amazing home full of awesome surprises! Amazing fresh home cooked breakfast, served with the warmest smile and Shannon has been superb in accommodating food requirements, catering to your needs. They have travelled themselves and thought of everything, you need it… you got it! Thank you for a memorable enjoyable stay, I only wish I could stay longer
United Kingdom
J
Reviewed June 24, 2024
Pillow and Paddock B&B