Photo by Southernmost Illinois Tourism Bureau
Search Spa Hotels in Southern Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois Spa Hotels
Our top choices for Southern Illinois hotels with a spa
9.4 out of 10, Exceptional, (443 reviews)
- Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
"The hot tub we enjoyed ...."
Matthew J
The price is ₹10,522
₹11,677 total
includes taxes & fees
14 May - 15 May
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
- Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
"Our stay was wonderful. The rooms are so nice. Bed was comfortable. The jaccuzi tub is excellent. The free breakfast was lovely. Even had healthy options with turkey sausage and egg white omelets. Delicious. "
Laura
The price is ₹9,934
₹11,207 total
includes taxes & fees
17 May - 18 May
8.4 out of 10, Very good, (139 reviews)
"I like how clean the rooms were. Water was nice and hot just didnt last long but thats okay. The only complaint would be it had a bad mildew smell. "
Brittany
The price is ₹10,407
₹11,550 total
includes taxes & fees
11 May - 12 May
8.6 out of 10, Excellent, (1,006 reviews)
- Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
"The spa was great and all the staff were perfect very polite!"
Charlotte
The price is ₹15,062
₹19,173 total
includes taxes & fees
25 May - 26 May
9.2 out of 10, Wonderful, (412 reviews)
- Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
"Jacuzzi tub clean and powerful."
Celina
The price is ₹8,071
₹10,921 total
includes taxes & fees
10 May - 11 May
9.0 out of 10, Wonderful, (1,822 reviews)
- Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
"Beautiful, repurposed hotel with gorgeous lobby, amazing art museum, top-notch pool and spa facilities, central location, and very comfortable and compact room."
Natalie
The price is ₹15,990
₹19,169 total
includes taxes & fees
10 May - 11 May
9.4 out of 10, Exceptional, (1,001 reviews)
- Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
"I would definitely come back here to rest and recharge."
Lynne
The price is ₹31,695
₹37,061 total
includes taxes & fees
10 May - 11 May
9.2 out of 10, Wonderful, (566 reviews)
- Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
"Top quality
Concierge floor worth the cost"
Norma E.
The price is ₹47,212
₹55,114 total
includes taxes & fees
24 May - 25 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews
Country Inn & Suites by Radisson, Effingham, IL
8/10 Good
Explore a world of travel with Expedia
- Car hire Alma
- Car hire Alto Pass
- Car hire Chester
- Car hire Colp
- Car hire Cutler
- Car hire Edgewood
- Car hire Energy
- Car hire near Fairfield Country Club
- Car hire Glendale
- Car hire Golden Gate
- Car hire Grand Tower
- Car hire Huey
- Car hire Louisville
- Car hire Macedonia
- Car hire Marion
- Rental cars MidAmerica-St. Louis airport
- Car hire Mount Erie
- Car hire Mount Vernon
- Car hire Nashville
- Car hire New Athens
- Car hire New Memphis
- Car hire Odin
- Car hire Omaha
- Car hire Raleigh
- Car hire Rockwood
- Car hire near Salem Fairgrounds
- Car hire near Salem Township Hospital
- Car hire Salem
- Car hire Scott Air Force Base
- Rental cars Southern Illinois airport
- Car hire Sparta
- Car hire St. Johns
- Car hire Trenton
- Car hire Vandalia
- Car hire Xenia
- Car hire near Washington County