Search Spa Hotels in Southern Illinois

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on Southern Illinois Spa Hotels

Top Southern Illinois Spa Hotels

Sauna, hot tub, body treatments, hot stone massages
Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 star property
9.4 out of 10, Exceptional, (378)
"The entire staff from front desk, bar, restaurant, housekeeping were so friendly!! I've never met so many friendly people in one place !!"
United States
Deborah
Walker's Bluff Casino Resort
Property entrance
1895 Washington Hotel
1895 Washington Hotel
3.0 star property
9.2 out of 10, Wonderful, (380)
"An absolutely charming B&B with a great history."
United States
Laurie
1895 Washington Hotel
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
9.4 out of 10, Exceptional, (1000)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is ₹8,354
₹9,424 total
includes taxes & fees
2 Nov - 3 Nov
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exclusive Room, 1 Queen Bed | Memory-foam beds, desk, laptop workspace, iron/ironing board
Arthur's Country Inn
Arthur's Country Inn
2.5 star property
8.4 out of 10, Very good, (130)
"We loved this Inn it was a unique experience in comparison to modern hotels but definitely a nice change. "
United States
Latasha
The price is ₹9,333
₹10,358 total
includes taxes & fees
25 Oct - 26 Oct
Arthur's Country Inn
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
8.4 out of 10, Very good, (1001)
"Great place to stay.Will visit again."
United States
Shameka
The price is ₹15,621
₹19,716 total
includes taxes & fees
26 Oct - 27 Oct
Ameristar Casino Resort and Spa
Massages
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 star property
9.0 out of 10, Wonderful, (1424)
"Unique hotel and very convenient to City Museum. "
United States
michael
The price is ₹12,583
₹14,713 total
includes taxes & fees
31 Oct - 1 Nov
21C Museum Hotel St Louis
Couples treatment room(s), hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
5.0 star property
9.4 out of 10, Exceptional, (1001)
"Beautiful stay at the four seasons! "
United States
Maria
The price is ₹37,371
₹43,698 total
includes taxes & fees
31 Oct - 1 Nov
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (551)
"Service is exceptional!!!"
United States
Jorge
The price is ₹44,758
₹52,250 total
includes taxes & fees
26 Oct - 27 Oct
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Cozy beds, clean rooms, hot shower"
Coral 1-night trip
Posted 4 days ago
Comfort Suites Mount Vernon

Explore a world of travel with Expedia