Photo by Southernmost Illinois Tourism Bureau

Southern Illinois Hotels from ₹5,582
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southern Illinois
Check prices for these dates
Our top choices for Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,653 reviews)
The price is ₹10,524
₹11,868 total
includes taxes & fees
5 Apr - 6 Apr

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (723 reviews)
The price is ₹10,288
₹11,418 total
includes taxes & fees
5 Apr - 6 Apr

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,000 reviews)
The price is ₹8,124
₹9,016 total
includes taxes & fees
5 Apr - 6 Apr

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,000 reviews)
The price is ₹9,107
₹10,198 total
includes taxes & fees
5 Apr - 6 Apr

Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1,007 reviews)
The price is ₹8,307
₹9,303 total
includes taxes & fees
5 Apr - 6 Apr

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,002 reviews)
The price is ₹10,055
₹11,347 total
includes taxes & fees
12 Apr - 13 Apr

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (936 reviews)
The price is ₹7,273
₹8,071 total
includes taxes & fees
5 Apr - 6 Apr

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (220 reviews)
The price is ₹10,284
₹11,414 total
includes taxes & fees
30 Mar - 31 Mar

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,012 reviews)
The price is ₹10,624
₹11,978 total
includes taxes & fees
19 Apr - 20 Apr

Walker's Bluff Casino Resort
Walker's Bluff Casino ResortCarterville
9.4 out of 10, Exceptional, (421 reviews)
The price is ₹10,380
₹11,520 total
includes taxes & fees
1 Apr - 2 Apr

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (668 reviews)
The price is ₹9,867
₹11,049 total
includes taxes & fees
19 Apr - 20 Apr

Hampton Inn Carbondale
Hampton Inn CarbondaleCarbondale
8.4 out of 10, Very good, (628 reviews)
The price is ₹11,482
₹13,202 total
includes taxes & fees
5 Apr - 6 Apr

Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (828 reviews)
The price is ₹7,907
₹8,539 total
includes taxes & fees
5 Apr - 6 Apr

Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ₹11,160
₹13,389 total
includes taxes & fees
12 Apr - 13 Apr

Quality Inn & Suites Metropolis I-24
Quality Inn & Suites Metropolis I-24Metropolis
8.0 out of 10, Very good, (1,002 reviews)
The price is ₹6,108
₹7,060 total
includes taxes & fees
5 Apr - 6 Apr

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ₹10,525
₹11,786 total
includes taxes & fees
5 Apr - 6 Apr

Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (823 reviews)
The price is ₹6,390
₹6,964 total
includes taxes & fees
1 Apr - 2 Apr

Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.0 out of 10, Very good, (1,001 reviews)
The price is ₹7,173
₹7,960 total
includes taxes & fees
12 Apr - 13 Apr

Comfort Suites Effingham Central
Comfort Suites Effingham CentralEffingham
8.8 out of 10, Excellent, (595 reviews)
The price is ₹8,787
₹9,839 total
includes taxes & fees
5 Apr - 6 Apr

Days Inn & Suites by Wyndham Casey
Days Inn & Suites by Wyndham CaseyCasey
7.4 out of 10, Good, (844 reviews)
The price is ₹6,259
₹6,946 total
includes taxes & fees
9 Apr - 10 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is ₹5,120 per night from 29 Mar to 30 Mar
₹5,120
₹5,887 total
29 Mar - 30 Mar
includes taxes & fees
7/10 Good! (1,005 reviews)
Hotels in Southern Illinois with star rating

4 Star Hotels
4 properties
Explore a world of travel with Expedia
- Car hire Alma
- Car hire Alto Pass
- Car hire Chester
- Car hire Colp
- Car hire Cutler
- Car hire Edgewood
- Car hire Energy
- Car hire near Fairfield Country Club
- Car hire Glendale
- Car hire Golden Gate
- Car hire Grand Tower
- Car hire Huey
- Car hire Louisville
- Car hire Macedonia
- Car hire Marion
- Rental cars MidAmerica-St. Louis airport
- Car hire Mount Erie
- Car hire Mount Vernon
- Car hire Nashville
- Car hire New Athens
- Car hire New Memphis
- Car hire Odin
- Car hire Omaha
- Car hire Raleigh
- Car hire Rockwood
- Car hire near Salem Fairgrounds
- Car hire near Salem Township Hospital
- Car hire Salem
- Car hire Scott Air Force Base
- Rental cars Southern Illinois airport
- Car hire Sparta
- Car hire St. Johns
- Car hire Trenton
- Car hire Vandalia
- Car hire Xenia
- Car hire near Washington County














































































