𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Southern Illinois (2026)

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

₹10,488

₹11,828 total

includes taxes & fees

13 Sept - 14 Sept

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a window providing natural light.

A hotel room with two beds, a large window, and a wall-mounted lamp.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

Abigail

₹11,150

₹12,563 total

includes taxes & fees

27 Sept - 28 Sept

A hotel lobby with a reception desk, seating area, and a large screen TV.

A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

A brick building with a patio area featuring wicker furniture and a table.

A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.

3. Comfort Suites Mount Vernon

Mount Vernon

James

₹11,113

₹12,522 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.

A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.

A reception area with a counter, a clock, and a chandelier.

4. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Matthew W,

₹7,276

₹8,264 total

includes taxes & fees

13 Sept - 14 Sept

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

A hotel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.

5. Quality Inn Mount Vernon, IL

Mount Vernon

Matthew

₹7,144

₹8,117 total

includes taxes & fees

20 Sept - 21 Sept

An indoor swimming pool with a diving board, a changing room, and a tiled floor.

A hotel room with two beds, a desk, a window with curtains, and a painting on the wall.

A living room with two gray armchairs, a coffee table, a flat-screen TV, and a fireplace. There are large windows and a potted plant.

A Days Inn building with a flat roof, large windows, and a sign above the entrance.

6. Days Inn by Wyndham Mount Vernon

Mount Vernon

Asa

₹6,827

₹7,766 total

includes taxes & fees

13 Sept - 14 Sept

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

An outdoor patio area with tables and chairs, large windows, and red umbrellas.

7. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Samuel

₹12,084

₹13,599 total

includes taxes & fees

1 Oct - 2 Oct

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

A hallway with vending machines and a carpeted floor.

A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.

A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

8. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

MARK

₹7,653

₹8,493 total

includes taxes & fees

15 Sept - 16 Sept

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A spacious lobby with a large seating area, a reception desk, and a television.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

9. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

₹13,134

₹14,708 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

A modern living area with a sectional sofa, a fireplace, and a flat-screen TV.

A hotel lobby with a large indoor pool, a reception desk, and a seating area.

A modern hotel lobby with a long dining table, bar stools, a sofa, and a fireplace.

10. Hampton Inn & Suites Effingham

Effingham

Kate

₹12,320

₹13,672 total

includes taxes & fees

20 Sept - 21 Sept

A Country Inn & Suites building with a covered entrance and a sign.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a no diving sign.

A restaurant with wooden tables and chairs, a coffee bar with various appliances, and a TV mounted on the wall.

A building with a green roof, white columns, and a glass entrance.

11. Country Inn & Suites by Radisson, Effingham, IL

Effingham

Larry

₹8,943

₹9,924 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel room with a large bed, a desk with a computer, a chair, a large window, a bathroom with a bathtub, and a green accent wall.

A hotel room with a large window, a blue sofa, a patterned armchair, a desk, and a television.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A grocery store aisle with shelves stocked with various food items and two refrigerated beverage dispensers.

12. Holiday Inn Express & Suites Effingham by IHG

Effingham

Sheridan

₹11,622

₹13,015 total

includes taxes & fees

13 Sept - 14 Sept

A reception area with a reception desk, a clock, a blue mat, and two potted plants.

A dining area with a central table surrounded by chairs, a kitchen area with appliances, and a sign that reads 'Coffee Anyone?'

A hotel room with a bed, bedside tables, a chair, and a window with curtains.

A hotel gym with cardio equipment, weight machines, and a mirrored wall.

13. Ramada by Wyndham Effingham

Effingham

Kristen

₹6,345

₹7,105 total

includes taxes & fees

13 Sept - 14 Sept

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A hotel room with a bed, a desk, a chair, a lamp, a mirror, and a television.

A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

14. Super 8 by Wyndham Troy IL/St. Louis Area

Troy

Donta

₹6,425

₹7,131 total

includes taxes & fees

15 Sept - 16 Sept

A hotel room with a bed, a desk, a television, and a bathroom.

A reception area with a stone wall, a reception desk, and a red patterned chair.

A wooden interior with a pool area, a white chair, and a view of the pool through a glass door.

A hotel room with a kitchenette, a dining area, a sofa, a bed, and a patterned carpet.

15. Quality Inn Effingham North

Effingham

Sierra

₹7,250

₹8,046 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with two beds, a desk, a chair, a TV, and a lamp.

A modern kitchen with a coffee station, seating area with tables and chairs, and a clock on the wall.

A reception area with a wooden counter, a television, and a sign reading "Baymont by Wyndham".

A compact kitchen with a refrigerator, a coffee maker, and a sink.

16. Baymont by Wyndham Effingham

Effingham

jamie

₹7,230

₹8,023 total

includes taxes & fees

16 Sept - 17 Sept

A hotel room with two beds, a desk, and a chair.

A large indoor swimming pool with a wooden ceiling and tiled floor, surrounded by windows and a door.

A spacious lobby with a seating area, a coffee station, and large windows providing natural light.

A reception area with a stone wall, a reception desk, a green wall with a sign, a wooden door, and a patterned rug.

17. Quality Inn & Suites Metropolis I-24

Metropolis

Cierra

₹5,404

₹6,280 total

includes taxes & fees

28 Sept - 29 Sept

An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

A spacious dining area with a long wooden table, multiple chairs, and pendant lighting.

A Best Western hotel with a modern facade, a parking lot, and a clear sky.

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a television, and a framed artwork on the wall.

18. Best Western Delta Inn

Effingham

Chris

₹8,353

₹9,354 total

includes taxes & fees

13 Sept - 14 Sept

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

A modern hotel room with a living area, a kitchenette, and a door leading to another room.

A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

19. Best Western Plus MidAmerica Hotel

Mascoutah

Justin

₹10,352

₹11,798 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.

An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.

An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.

20. Drury Inn & Suites Marion

Marion

Suzanne

₹8,692

₹10,429 total

includes taxes & fees

20 Sept - 21 Sept

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Holiday Rentals in Southern Illinois

Cottage

A modern kitchen with dark cabinets, a round dining table, and a tufted bench.

A single-story house with a front porch, a mailbox, and a wreath on the door.

A modern living room with a flat-screen TV, wooden entertainment unit, leather sofa, and a dining table.

A bedroom with a bed, a chair, a window, and two framed pictures on the wall.

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Robinson

Cottage

A living room with a fireplace, leather sofas, and a clock on the wall.

A room with a wooden wall, a window with a view of a deck and outdoor area, and a potted plant with flowers on a table.

A spacious living room with leather sofas, a dining table, and a ceiling fan.

A modern kitchen with wooden cabinets, a white refrigerator, and a microwave. There is a dining area with a table and chairs, and a living room with a couch and a fireplace.

Illinois Vacation Rental Home: Pets Welcome

Palestine

Cottage

A long, narrow hallway with wooden floors and large windows.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a tiled floor.

A single-story house with a front porch, a central entrance, and a small staircase leading to the door.

A modern kitchen with a stainless steel refrigerator, oven, and dishwasher. There is a wooden dining table and a brick accent wall.

Cozy Anna Home Near Southern Illinois Attractions!

Anna

"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."

Cottage

A modern kitchen with white cabinetry, a coffee maker, a sink, a dishwasher, and a built-in oven.

A modern kitchen with white cabinets, a wooden dining table, and black chairs.

A living room with a beige sectional sofa, a wooden coffee table, a patterned rug, and a small side table with a lamp.

A hallway with a white door, a mirror, a lamp, and a basket on a console table.

Country Home Near EIU & Lake Charleston!

Charleston

"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...

Cottage

A covered porch with a 'WELCOME' sign, wooden chairs, and a small table.

A living room with a sofa, coffee table, TV stand, and a ceiling fan.

A modern kitchen with a dining area, stainless steel appliances, and a welcome sign.

A bedroom with a bunk bed, a ceiling fan, a TV mounted on the wall, and a window with blinds.

Mins to Local Attractions: Pet Friendly w/ Yard!

Casey

"Property was very clean and quiet, will definitely schedule for next family reunion."

Cottage

A covered porch with blue plastic chairs, a ceiling fan, and large windows offering a view of the outdoors.

A kitchen with wooden cabinets, a microwave, a dishwasher, and a dining area with chairs and a table.

A bedroom with a bed, a nightstand, a mirror, a ceiling fan, and a door leading to a bathroom.

A single-story house with a stone foundation and a gabled roof, surrounded by a small lawn and a wooden fence.

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg

"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."

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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

See properties

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)

This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.

See properties

Harrah's Metropolis

8.0/10 (310 reviews)

This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards programme to maximise your experience while enjoying Southern classics at the on-site restaurants.

See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois

Top Southern Illinois Hotel Reviews

Super 8 by Wyndham Mt. Vernon IL

10/10 Excellent

"Very nice place clean comfortable and very accommodating"

The Principal Hotel

10/10 Excellent

"This property, is a prime example of how a developer can repurpose a church a Convent a school and all their amenities in a very respectful and meaningful way. As a former Catholic and going to Catholic grade school and high schools I loved the naming of everything involved the repurposing of lockers in the hallways and the pews probably from the church in the hallways for you to sit down or sit your things on. Just the name Graphite for the restaurant, the Do Not Disturb door sign was Class in Session. The Cafe on the Abbey was great food and catering. I highly recommed the Principal Hotel for anyone visiting the St Louis area and wants a place to enjoy without the rush!"

Holiday Inn Express Metropolis by IHG

10/10 Excellent

"Very nice people. Very clean. Good breakfast"

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent

"My son and I stayed here for a couple of days while I was in town visiting family over Labor Day weekend. The front desk person, Romello (sorry if I spelled your name wrong), was super nice and welcoming. All of the other staff we encountered throughout our stay were great as well. My son especially loved the pool. It was definitely his favorite part of the stay. The Marketplace downstairs was also really convenient for grabbing a quick snack or something to drink without having to leave the hotel. Overall, we had a great stay and really enjoyed our time here. We would definitely stay again when we’re back in town."

Comfort Suites Mount Vernon

10/10 Excellent

"Nice staff at front desk"

Motel 6 Caseyville, IL - Caseyville Il

8/10 Good

"thanks"

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"It was Very loud some nights. And the hallways smelt like marijuana. Next time I think we will be staying some where else."

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"This is a very solid hotel. The room was clean and pretty large. The breakfast had lots of options. And the fitness center was decent--two treadmills, an elliptical, and free weights in a nice clean room. There's also a pool. And theres lots of stuff nearby for shopping and eating."

Quality Inn & Suites Metropolis I-24

10/10 Excellent

"Room was clean and bright, the air was on so Ithe room felt amazing and the pool was warm."

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

₹5,060

₹5,818 total

22 Sept - 23 Sept

includes taxes & fees

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

₹5,207

₹5,987 total

5 Oct - 6 Oct

includes taxes & fees

Best Western Delta Inn

1509 Hampton Dr Effingham IL

₹8,353

₹9,354 total

13 Sept - 14 Sept

includes taxes & fees

9/10 Wonderful! (1,006 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

₹8,259

₹9,909 total

29 Sept - 30 Sept

includes taxes & fees

8.4/10 Very good! (1,098 reviews)

Country Inn & Suites by Radisson, Effingham, IL

1200 N Raney Effingham IL

₹8,943

₹9,924 total

13 Sept - 14 Sept

includes taxes & fees

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

₹9,449

₹10,865 total

29 Sept - 30 Sept

includes taxes & fees

8.4/10 Very good! (929 reviews)

Hotels in Southern Illinois with star rating

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Motels in Grand Tower

Book Hotels in Southern Illinois on Expedia.com

Southern Illinois Hotels from ₹5,818

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southern Illinois

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southern Illinois hotels

1. Drury Plaza Hotel Mt. Vernon

2. Holiday Inn Express & Suites Mount Vernon by IHG

3. Comfort Suites Mount Vernon

4. Super 8 by Wyndham Mt. Vernon IL

5. Quality Inn Mount Vernon, IL

6. Days Inn by Wyndham Mount Vernon

7. DoubleTree by Hilton Mt. Vernon

8. SureStay Hotel by Best Western Whittington Rend Lake

9. Best Western Plus Centralia Hotel & Suites

10. Hampton Inn & Suites Effingham

11. Country Inn & Suites by Radisson, Effingham, IL

12. Holiday Inn Express & Suites Effingham by IHG

13. Ramada by Wyndham Effingham

14. Super 8 by Wyndham Troy IL/St. Louis Area

15. Quality Inn Effingham North

16. Baymont by Wyndham Effingham

17. Quality Inn & Suites Metropolis I-24

18. Best Western Delta Inn

19. Best Western Plus MidAmerica Hotel

20. Drury Inn & Suites Marion

Holiday Rentals in Southern Illinois

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Illinois Vacation Rental Home: Pets Welcome

Cozy Anna Home Near Southern Illinois Attractions!

Country Home Near EIU & Lake Charleston!

Mins to Local Attractions: Pet Friendly w/ Yard!

Harrisburg Home w/ Private Yard + Screened Porch!

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

World Wide Technology Raceway

O'Fallon Family Sports Park

Harrah's Metropolis

Learn more about Southern Illinois

Top Southern Illinois Hotel Reviews

Super 8 by Wyndham Mt. Vernon IL

The Principal Hotel

Holiday Inn Express Metropolis by IHG

Drury Inn & Suites St. Louis Fairview Heights

Comfort Suites Mount Vernon

Motel 6 Caseyville, IL - Caseyville Il

Drury Inn & Suites St. Louis O'Fallon, IL

Comfort Inn Edwardsville - St. Louis

Quality Inn & Suites Metropolis I-24

More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon

Americas Best Value Inn Collinsville St. Louis

Best Western Delta Inn

Baymont by Wyndham Marion

Country Inn & Suites by Radisson, Effingham, IL

Comfort Inn Edwardsville - St. Louis

Hotels in Southern Illinois with star rating

Explore a world of travel with Expedia

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