Southern Illinois Hotels from โน5,640
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Go beyond your typical stay in Southern Illinois
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Check prices for these dates
Tonight
18 Aug - 19 AugTomorrow
19 Aug - 20 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Southern Illinois hotels
1. Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
Kirstyn
โน10,592
โน11,946 total
includes taxes & fees
7 Sept - 8 Sept
2. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
Angela D
โน11,261
โน12,689 total
includes taxes & fees
28 Aug - 29 Aug
3. Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
Erica
โน11,674
โน13,146 total
includes taxes & fees
6 Sept - 7 Sept
4. Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon ILMount Vernon
Matthew W,
โน6,700
โน7,626 total
includes taxes & fees
30 Aug - 31 Aug
5. DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. VernonMount Vernon
Samuel
โน12,227
โน13,760 total
includes taxes & fees
3 Sept - 4 Sept
6. Quality Inn Mount Vernon, IL
Quality Inn Mount Vernon, ILMount Vernon
Kristin
โน7,215
โน8,198 total
includes taxes & fees
6 Sept - 7 Sept
7. SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
Debbie
โน7,648
โน8,488 total
includes taxes & fees
19 Aug - 20 Aug
8. Days Inn by Wyndham Mount Vernon
Days Inn by Wyndham Mount VernonMount Vernon
Norberto
โน6,895
โน7,843 total
includes taxes & fees
20 Aug - 21 Aug
9. Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & SuitesCentralia
Corey
โน14,220
โน15,923 total
includes taxes & fees
8 Sept - 9 Sept
10. Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
Amy
โน6,908
โน7,666 total
includes taxes & fees
30 Aug - 31 Aug
11. Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
Donna
โน10,306
โน11,129 total
includes taxes & fees
19 Aug - 20 Aug
12. Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
Sheridan
โน10,900
โน12,205 total
includes taxes & fees
23 Aug - 24 Aug
13. Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
Tara
โน10,134
โน12,159 total
includes taxes & fees
23 Aug - 24 Aug
14. Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51Vandalia
Cherilyn
โน6,994
โน7,621 total
includes taxes & fees
6 Sept - 7 Sept
15. Best Western Marion Hotel
Best Western Marion HotelMarion
Lauren
โน5,881
โน7,056 total
includes taxes & fees
19 Aug - 20 Aug
16. Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis AreaTroy
Donta
โน6,490
โน7,202 total
includes taxes & fees
27 Aug - 28 Aug
17. Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
Sierra
โน7,301
โน8,102 total
includes taxes & fees
30 Aug - 31 Aug
18. Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
Kate
โน11,682
โน12,964 total
includes taxes & fees
6 Sept - 7 Sept
19. Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
Jaysen
โน9,615
โน10,959 total
includes taxes & fees
30 Aug - 31 Aug
20. Baymont by Wyndham Marion
Baymont by Wyndham MarionMarion
james
โน8,175
โน9,808 total
includes taxes & fees
20 Aug - 21 Aug
Holiday Rentals in Southern Illinois
Cottage
Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg Home w/ Private Yard + Screened Porch!Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Apartment
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Murphysboro Retreat w/ Deck Near Kinkaid Lake!Murphysboro
"This is a very clean and nice apartment within a very close drive to the Kinkaid boat launch. Easy to locate and can fit a car with a boat in tow no problem. This spot was also much more quiet than the campground or RV spots nearby. They have a great porch and a grill and we didnโt bring something for it which made me sad. "
Cottage
Peaceful Robinson Home w/ Yard, Near Golf Courses!
Peaceful Robinson Home w/ Yard, Near Golf Courses!Robinson
Cottage
Illinois Vacation Rental Home: Pets Welcome
Illinois Vacation Rental Home: Pets WelcomePalestine
Cottage
Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!Anna
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
Cottage
Country Home Near EIU & Lake Charleston!
Country Home Near EIU & Lake Charleston!Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Cottage
Mins to Local Attractions: Pet Friendly w/ Yard!
Mins to Local Attractions: Pet Friendly w/ Yard!Casey
"Property was very clean and quiet, will definitely schedule for next family reunion."
Cottage
Beautiful Makanda Cabin in Shawnee National Forest
Beautiful Makanda Cabin in Shawnee National ForestMakanda
"It was very peaceful and relaxing. "
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Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburgโs unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Harrah's Metropolis
8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards programme to maximise your experience while enjoying Southern classics at the on-site restaurants.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
See all hotels in Southern Illinois
Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Second time here, just a stop off the freeway, very nice!"
Best Western St. Louis Fairview Heights
8/10 Good
"The staff was very kind. This is an old hotel that they have remodeled so it is still old just new paint etc. Breakfast was a little limited but everything was fine for a quick one night stay!"
Comfort Inn Edwardsville - St. Louis
8/10 Good
"Breakfast was vary goods Well stocked"
Drury Inn & Suites Marion
10/10 Excellent
"Travelled solo with 2 dogs. Staff were so helpful. They held leashes so I could grab food and then we're nice enough to take my tray to my room. Excellent customer service"
Holiday Inn Express Metropolis by IHG
8/10 Good
"The room is very clean you could tell that they've done work on the property since the last time I stayed. My only complaint was the footsteps I could hear above and the television options. But a very clean comfortable place to stay."
Ramada by Wyndham Effingham
10/10 Excellent
"Great basic hotel for the price! Fantastic place to stay and pinch pennies"
Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"Nice"
The Principal Hotel
10/10 Excellent
"Very clean and new rooms. Cassie was great at the front desk. I recommend the principal hotel"
Country Inn & Suites by Radisson, Effingham, IL
10/10 Excellent
"Staff member very helpful when i made a small error in my reservation. He gave me the room that i had meant to reserve"
More cheap stays in Southern Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
โน4,905
โน5,640 total
19 Aug - 20 Aug
includes taxes & fees
Baymont by Wyndham Effingham
1811 W Fayette Avenue Effingham IL
โน6,908
โน7,666 total
30 Aug - 31 Aug
includes taxes & fees
Best Western St. Louis Fairview Heights
150 Ludwig Dr Fairview Heights IL
โน7,626
โน8,616 total
27 Aug - 28 Aug
includes taxes & fees
7.2/10 Good! (91 reviews)
Baymont by Wyndham Marion
2608 W Main St Marion IL
โน8,175
โน9,808 total
20 Aug - 21 Aug
includes taxes & fees
Holiday Inn Express Metropolis by IHG
2179 East 5th Street Metropolis IL
โน10,021
โน11,121 total
8 Sept - 9 Sept
includes taxes & fees
8.8/10 Excellent! (1,010 reviews)
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
โน11,674
โน13,146 total
6 Sept - 7 Sept
includes taxes & fees
9/10 Wonderful! (1,075 reviews)
Hotels in Southern Illinois with star rating
4 Star Hotels
4 properties
3 Star Hotels
81 properties
2 Star Hotels
218 properties
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