A tree with sunlight filtering through its leaves, creating a warm glow.

Search Spa Hotels in Sikeston

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Sikeston Spa Hotels

Tonight
17 Sept - 18 Sept
Tomorrow
18 Sept - 19 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for Sikeston hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
₹9,692
₹11,030 total
includes taxes & fees
4 Oct - 5 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
View all properties

Choose what matters most at spa hotels in Sikeston

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Sikeston Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Sikeston?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers like the gourmet restaurants and popular shops in Sikeston. Enjoy the museums and riverfront during your holiday. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your stay.
What's there to see and do in Sikeston?
Experience Sikeston and visit Central Park, Hunter-Dawson State Historic Site and Sikeston Depot Museum. If you have a little extra time during your trip, you might want to make a stop at Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery.
What is a Sikeston spa hotel?
Spa hotels in Sikeston provide lodging and have an on-site spa offering services including facials and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your holiday.

Explore a world of travel with Expedia