Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.

Sikeston Hotels from ₹5,706
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Our top choices for Sikeston hotels

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ₹7,716
₹8,158 total
includes taxes & fees
3 May - 4 May

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ₹9,410
₹10,616 total
includes taxes & fees
3 May - 4 May

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (752 reviews)
The price is ₹8,385
₹9,075 total
includes taxes & fees
26 Apr - 27 Apr

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
The price is ₹9,882
₹11,148 total
includes taxes & fees
17 May - 18 May

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (176 reviews)
The price is ₹8,719
₹9,837 total
includes taxes & fees
14 May - 15 May

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (121 reviews)
The price is ₹9,183
₹10,452 total
includes taxes & fees
24 May - 25 May

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,006 reviews)
The price is ₹8,012
₹9,131 total
includes taxes & fees
3 May - 4 May

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (806 reviews)
The price is ₹9,955
₹11,231 total
includes taxes & fees
3 May - 4 May

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,004 reviews)
The price is ₹6,869
₹7,749 total
includes taxes & fees
3 May - 4 May

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is ₹9,034
₹10,191 total
includes taxes & fees
3 May - 4 May

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,003 reviews)
The price is ₹10,351
₹11,901 total
includes taxes & fees
26 Apr - 27 Apr

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (769 reviews)
The price is ₹6,117
₹6,974 total
includes taxes & fees
3 May - 4 May

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
The price is ₹6,098
₹6,951 total
includes taxes & fees
26 Apr - 27 Apr

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (553 reviews)
The price is ₹11,417
₹12,880 total
includes taxes & fees
19 May - 20 May

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (72 reviews)
The price is ₹10,352
₹11,721 total
includes taxes & fees
3 May - 4 May

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (460 reviews)
The price is ₹9,882
₹11,189 total
includes taxes & fees
3 May - 4 May

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.2 out of 10, Good, (730 reviews)
The price is ₹6,258
₹7,060 total
includes taxes & fees
27 Apr - 28 Apr

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (544 reviews)
The price is ₹9,569
₹10,835 total
includes taxes & fees
3 May - 4 May

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (503 reviews)
The price is ₹13,467
₹15,260 total
includes taxes & fees
20 May - 21 May

Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
10.0 out of 10, Exceptional, (22 reviews)
The price is ₹9,183
₹10,312 total
includes taxes & fees
3 May - 4 May
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Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Top Sikeston Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
8/10 Good
More cheap stays in Sikeston

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
The price is ₹6,098 per night from 26 Apr to 27 Apr
₹6,098
₹6,951 total
26 Apr - 27 Apr
includes taxes & fees
7.2/10 Good! (1,001 reviews)
Hotels in Sikeston with star rating

3 Star Hotels
17 properties
Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
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The Sikeston info point: What you need to know
Category | Details |
|---|---|
| Location | Sikeston, Missouri, United States |
| Population | Approximately 16,000 |
| Climate | Humid subtropical |
| Best time to visit | Spring and fall |
| Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
| Local cuisine | Barbecue, Southern comfort food |
| Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
| Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
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