Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.
Photo by Ryan Coleman
Sikeston Hotels from ₹5,876
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Top 10 Sikeston hotels and places to stay

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
9.4 out of 10, Exceptional, (1005)
The price is ₹7,777
₹8,941 total
includes taxes & fees
14 Aug - 15 Aug

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
9.4 out of 10, Exceptional, (962)
The price is ₹7,772
₹8,767 total
includes taxes & fees
29 Jul - 30 Jul

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
9.4 out of 10, Exceptional, (1006)
The price is ₹8,383
₹9,457 total
includes taxes & fees
22 Aug - 23 Aug

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1011)
The price is ₹7,772
₹8,767 total
includes taxes & fees
28 Jul - 29 Jul

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
9.6 out of 10, Exceptional, (728)
The price is ₹9,470
₹10,684 total
includes taxes & fees
2 Aug - 3 Aug

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
9.8 out of 10, Exceptional, (15)
The price is ₹10,278
₹11,637 total
includes taxes & fees
27 Jul - 28 Jul
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Sikeston and related destinations
Explore Sikeston: its dining, riverfront, museums and more!

Photo by Ryan Coleman
Open Photo by Ryan Coleman
More cheap stays in Sikeston
More cheap stays in Sikeston

The Riverview
777 Main St, Cape Girardeau, MO
The price is ₹9,095 per night from 27 Jul to 28 Jul
₹9,095
₹10,260 total
27 Jul - 28 Jul
includes taxes & fees
9.2/10 Wonderful! (355 reviews)
Hotels in Sikeston with star rating
Hotels in Sikeston with star rating

3 Star Hotels
15 properties
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Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
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The Sikeston info point: What you need to know
Category | Details |
---|---|
Location | Sikeston, Missouri, United States |
Population | Approximately 16,000 |
Climate | Humid subtropical |
Best time to visit | Spring and fall |
Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
Local cuisine | Barbecue, Southern comfort food |
Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
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