Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.

Sikeston Hotels from ₹5,920
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Our top choices for Sikeston hotels

1. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (652 reviews)
The price is ₹9,574
₹10,888 total
includes taxes & fees
22 Nov - 23 Nov

2. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,000 reviews)
The price is ₹8,896
₹10,228 total
includes taxes & fees
15 Nov - 16 Nov

3. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.8 out of 10, Excellent, (520 reviews)
The price is ₹8,992
₹10,226 total
includes taxes & fees
6 Dec - 7 Dec

4. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,004 reviews)
The price is ₹7,028
₹8,010 total
includes taxes & fees
3 Dec - 4 Dec

5. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is ₹9,559
₹10,871 total
includes taxes & fees
15 Nov - 16 Nov

6. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (29 reviews)
The price is ₹9,976
₹11,345 total
includes taxes & fees
15 Nov - 16 Nov

7. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.4 out of 10, Good, (1,000 reviews)
The price is ₹6,275
₹7,152 total
includes taxes & fees
8 Nov - 9 Nov

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (829 reviews)
The price is ₹6,051
₹6,897 total
includes taxes & fees
15 Nov - 16 Nov

9. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very good, (322 reviews)
The price is ₹8,253
₹9,407 total
includes taxes & fees
30 Nov - 1 Dec

10. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
7.0 out of 10, Good, (695 reviews)
The price is ₹5,486
₹6,252 total
includes taxes & fees
15 Nov - 16 Nov

11. Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (163 reviews)
The price is ₹4,976
₹5,920 total
includes taxes & fees
6 Nov - 7 Nov

12. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ₹9,367
₹10,568 total
includes taxes & fees
15 Nov - 16 Nov

13. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ₹8,992
₹10,234 total
includes taxes & fees
6 Dec - 7 Dec

14. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (890 reviews)
The price is ₹7,562
₹8,184 total
includes taxes & fees
8 Nov - 9 Nov

15. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,000 reviews)
The price is ₹6,814
₹7,687 total
includes taxes & fees
15 Nov - 16 Nov

16. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (240 reviews)
The price is ₹9,574
₹10,800 total
includes taxes & fees
12 Nov - 13 Nov

17. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (858 reviews)
The price is ₹9,236
₹10,419 total
includes taxes & fees
15 Nov - 16 Nov

18. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ₹8,517
₹9,609 total
includes taxes & fees
13 Nov - 14 Nov

19. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (557 reviews)
The price is ₹10,989
₹12,452 total
includes taxes & fees
15 Nov - 16 Nov

20. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
The price is ₹10,061
₹11,350 total
includes taxes & fees
9 Nov - 10 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

More cheap stays in Sikeston

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
The price is ₹5,486 per night from 15 Nov to 16 Nov
₹5,486
₹6,252 total
15 Nov - 16 Nov
includes taxes & fees
7/10 Good! (695 reviews)
Hotels in Sikeston with star rating

3 Star Hotels
21 properties
Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
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The Sikeston info point: What you need to know
Category | Details |
|---|---|
| Location | Sikeston, Missouri, United States |
| Population | Approximately 16,000 |
| Climate | Humid subtropical |
| Best time to visit | Spring and fall |
| Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
| Local cuisine | Barbecue, Southern comfort food |
| Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
| Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
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