Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.

Sikeston Hotels from ₹5,410
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Our top choices for Sikeston hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,012 reviews)
The price is ₹9,636
₹11,079 total
includes taxes & fees
14 May - 15 May

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,006 reviews)
The price is ₹9,896
₹11,164 total
includes taxes & fees
17 May - 18 May

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
The price is ₹9,447
₹10,658 total
includes taxes & fees
14 May - 15 May

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (506 reviews)
The price is ₹12,639
₹14,321 total
includes taxes & fees
24 May - 25 May

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (556 reviews)
The price is ₹9,970
₹11,288 total
includes taxes & fees
21 May - 22 May

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,007 reviews)
The price is ₹8,786
₹9,912 total
includes taxes & fees
17 May - 18 May

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (179 reviews)
The price is ₹8,754
₹9,876 total
includes taxes & fees
31 May - 1 Jun

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (761 reviews)
The price is ₹9,246
₹10,005 total
includes taxes & fees
18 May - 19 May

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,005 reviews)
The price is ₹6,802
₹7,673 total
includes taxes & fees
17 May - 18 May

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,002 reviews)
The price is ₹8,511
₹9,701 total
includes taxes & fees
10 May - 11 May

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,007 reviews)
The price is ₹8,219
₹8,690 total
includes taxes & fees
7 Jun - 8 Jun

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (462 reviews)
The price is ₹9,543
₹10,805 total
includes taxes & fees
7 Jun - 8 Jun

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (565 reviews)
The price is ₹11,098
₹12,520 total
includes taxes & fees
3 Jun - 4 Jun

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (125 reviews)
The price is ₹9,197
₹10,467 total
includes taxes & fees
25 May - 26 May

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (811 reviews)
The price is ₹9,970
₹11,247 total
includes taxes & fees
31 May - 1 Jun

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is ₹11,999
₹13,586 total
includes taxes & fees
21 May - 22 May

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (75 reviews)
The price is ₹10,393
₹11,768 total
includes taxes & fees
28 May - 29 May

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
The price is ₹12,889
₹14,541 total
includes taxes & fees
14 May - 15 May

Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.2 out of 10, Very good, (765 reviews)
The price is ₹8,685
₹9,399 total
includes taxes & fees
24 May - 25 May

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.2 out of 10, Good, (739 reviews)
The price is ₹6,293
₹7,099 total
includes taxes & fees
17 May - 18 May
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Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Top Sikeston Hotel Reviews

Drury Inn & Suites Jackson MO
10/10 Excellent
More cheap stays in Sikeston

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
The price is ₹5,952 per night from 10 May to 11 May
₹5,952
₹6,784 total
10 May - 11 May
includes taxes & fees
6.8/10 (622 reviews)
Hotels in Sikeston with star rating

3 Star Hotels
17 properties
Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
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The Sikeston info point: What you need to know
Category | Details |
|---|---|
| Location | Sikeston, Missouri, United States |
| Population | Approximately 16,000 |
| Climate | Humid subtropical |
| Best time to visit | Spring and fall |
| Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
| Local cuisine | Barbecue, Southern comfort food |
| Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
| Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
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