TOP Boutique Hotels in Santa Cruz for 2026

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Our top choices for Santa Cruz boutique hotels

Panoramic Penthouse, Terrace, City View (Pool) | Premium bedding, down duvets, in-room safe, individually decorated

Hotel Boutique Corral del Rey by ALUZ Collection

Historical Center

Katie

₹14,607 total

includes taxes & fees

14 Jul - 15 Jul

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Historical Center

Mandip

₹44,039 total

includes taxes & fees

19 Jul - 20 Jul

Hotel Boutique Casa del Poeta Sevilla

Historical Center

Jon

₹21,235 total

includes taxes & fees

24 Jul - 25 Jul

Hotel Amadeus Sevilla

Historical Center

Stephen

₹13,369 total

includes taxes & fees

28 Jun - 29 Jun

Las Casas de la Judería, Sevilla Historic City Center

Historical Center

Eleanor Louise

₹15,533 total

includes taxes & fees

5 Jul - 6 Jul

EME Catedral Mercer Hotel

Historical Center

Rachel

₹17,529 total

includes taxes & fees

5 Jul - 6 Jul

Hotel Doña Maria

Historical Center

Rajeev

₹12,367 total

includes taxes & fees

7 Jul - 8 Jul

Outdoor pool, pool umbrellas, pool loungers

Los Seises Sevilla, a Tribute Portfolio Hotel

Historical Center

Dorothy

₹15,365 total

includes taxes & fees

7 Jul - 8 Jul

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Top Santa Cruz Hotel Reviews

Hotel Murillo

10/10 Excellent

"Instalaciones muy ordenadas y limpias , el almuerzo muy bueno"

Las Casas de la Judería, Sevilla Historic City Center

10/10 Excellent

"Truly magical property, good location, friendly staff and lovely room in the annexe. Only downside is the lack of space at the rooftop pool which could be better managed to stop campers. Otherwise it is a lovely outdoor space."

Hotel Amadeus Sevilla

10/10 Excellent

"The location is unbeatable—right in the heart of Seville and within easy walking distance of the Cathedral, the Royal Alcázar, and countless restaurants, cafés, and shops. We barely needed transportation because everything was so close. The hotel is spotless, beautifully maintained, and smells wonderful throughout. One of my favorite touches was the soft classical music playing throughout the hotel, creating a relaxing and elegant atmosphere. What truly made our stay memorable was the exceptional hospitality. A heartfelt thank you to Victoria, Adelino, and Rocío for making us feel so welcome. A very special shout-out to Adelino. We had a minor issue with our room late at night, and at around 1:00 a.m., he handled it with kindness, professionalism, and genuine care. He quickly arranged for us to move to another room, ensuring we were comfortable and could enjoy the rest of our stay. That level of customer service is something you don't forget. Hotel Amadeus exceeded our expectations in every way. If we ever return to Seville and we certainly hope to we will definitely stay here again. Highly recommended!"

Hotel Doña Maria

10/10 Excellent

"So this hotel surpassed our expectations 100%! It was a beautiful historic hotel . Wonderful location across road from the Seville Cathedral . Close to restaurants, souvenir shops & bars & tourist attractions . Pool and bar area was spacious, & staff were lovely . Exceptional good value for what we paid ."

Frequently asked questions

Searching for a cosy accommodation option when you visit Santa Cruz?

A boutique hotel may be just what you want if you enjoy smaller hotels with quality service and a cool atmosphere. Select from 17 boutique-style accommodation options in Santa Cruz to find a property that characterises the local flavour of this destination.

What's the best boutique-style accommodation in Santa Cruz?

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville is a favourite hotel with Expedia travellers looking for a stylish stay, and features 2 restaurants and a garden. Las Casas de la Judería, Sevilla Historic City Center and Hotel Amadeus Sevilla are a couple of other boutique hotels.

How many boutique hotels should I expect to find in Santa Cruz?

Expedia has 17 boutique hotels in Santa Cruz.

What's there to see and do in Santa Cruz?

Visitors speak positively about this destination's fantastic nightlife, cultural attractions and stunning cathedral. Activities and attractions to experience around Santa Cruz include Giralda Tower, General Archive of the Indies and Murillo Gardens. While you're here, you might also like to explore more of the area and take in additional sights like Convent of the Incarnation, Archbishop's Palace and Archiddiocesis de Sevilla.

What's the best way to get to my boutique hotel in Santa Cruz?

You have a few options for travelling to and around Santa Cruz. The closest major airport is Seville (SVQ-San Pablo), which is located 5.7 mi (9.1 km) away. Make your way to Puerta Jerez Tram Stop for metro travel.

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Change your mind

Treat yourself

Be picky

Check availability on Santa Cruz Boutique Hotels

Our top choices for Santa Cruz boutique hotels

Hotel Boutique Corral del Rey by ALUZ Collection