East Prairie Travel Guide

Tourist Guide

The Mississippi River near Hannibal, Missouri, USA
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is ₹10,538 per night from 22 Jun to 23 Jun
₹10,538
₹12,116 total
22 Jun - 23 Jun
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,006 reviews)
"Clean rooms and was ready when we arrived. We did not use the pool but other guests were enjoying it. Breakfast and Kick back were both great meals."

Reviewed on 4 Jun 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is ₹10,947 per night from 2 Jul to 3 Jul
₹10,947
₹12,395 total
2 Jul - 3 Jul
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (573 reviews)
"The doughnuts and fry potatoes for breakfast were delicious"

Reviewed on 2 Jun 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is ₹8,658 per night from 14 Jun to 15 Jun
₹8,658
₹9,868 total
14 Jun - 15 Jun
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,004 reviews)
"Very convenient and staff was great."

Reviewed on 2 Jun 2026

Best Western Plus Sikeston I-55
See all 90 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Prime Fishing & Boating: Tiptonville Home

Prime Fishing & Boating: Tiptonville Home

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking and air conditioning. Popular attractions Tiptonville Public Library and Lake County Recreational Park ...
Prime Fishing & Boating: Tiptonville Home
Gloria's on Exchange

Gloria's on Exchange

3.5 out of 5
622 Exchange St Union City TN
Stay at this business-friendly holiday home in Union City. Enjoy free Wi-Fi, free parking and a snack bar/deli. Popular attractions Kiwanis Park and Union City ...
10/10 Exceptional! (2 reviews)
"Love love love Gloria’s and love Julie and David they are the best hosts."

Reviewed on 3 Jul 2019

Gloria's on Exchange
Boat Dock on Reelfoot Lake: Tiptonville Retreat

Boat Dock on Reelfoot Lake: Tiptonville Retreat

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking, a marina and balconies. Popular attractions Grassy Island and Horse Island are located nearby.
Boat Dock on Reelfoot Lake: Tiptonville Retreat
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park