East Prairie Travel Guide

Tourist Guide

The Mississippi River near Hannibal, Missouri, USA
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is ₹10,336 per night from 7 May to 8 May
₹10,336
₹11,883 total
7 May - 8 May
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,005 reviews)
👍

Reviewed on 19 Apr 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is ₹10,086 per night from 10 May to 11 May
₹10,086
₹11,420 total
10 May - 11 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (542 reviews)
The staff wS friebdly and helpful, upon arrival. The room was very clean and welcoming. The staff was able to accommodate our needs, with a smile. The breakfast was a great welcome to another beautiful day! Very plentiful and well stocked. Thank you and your great for great visit. We'll be back ...

Reviewed on 19 Apr 2026

Hampton Inn Sikeston
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is ₹6,034 per night from 26 Apr to 27 Apr
₹6,034
₹6,878 total
26 Apr - 27 Apr
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (1,000 reviews)
It had a clean room. Better than most hotels like this. The bathroom smelled like mold or mildew. And the lobby smelled of moth balls. Some of the sheets had black stuff on them. Not sure what it was. Air conditioning was cold.

Reviewed on 12 Apr 2026

Days Inn and Suites by Wyndham Sikeston
See all 85 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Prime Fishing & Boating: Tiptonville Home

Prime Fishing & Boating: Tiptonville Home

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking and air conditioning. Popular attractions Tiptonville Public Library and Lake County Recreational Park ...
Prime Fishing & Boating: Tiptonville Home
Gloria's on Exchange

Gloria's on Exchange

3.5 out of 5
622 Exchange St Union City TN
Stay at this business-friendly holiday home in Union City. Enjoy free Wi-Fi, free parking and a snack bar/deli. Popular attractions Kiwanis Park and Union City ...
10/10 Exceptional! (2 reviews)
Love love love Gloria’s and love Julie and David they are the best hosts.

Reviewed on 3 Jul 2019

Gloria's on Exchange
Boat Dock on Reelfoot Lake: Tiptonville Retreat

Boat Dock on Reelfoot Lake: Tiptonville Retreat

3 out of 5
Tiptonville TN
Stay at this cottage in Tiptonville. Enjoy free parking, a marina and balconies. Popular attractions Grassy Island and Horse Island are located nearby.
Boat Dock on Reelfoot Lake: Tiptonville Retreat
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park