
East Prairie Hotels from ₹4,883
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in East Prairie
Family friendly
Check prices for these dates
Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,003 reviews)
The price is ₹10,535
₹12,112 total
includes taxes & fees
15 May - 16 May

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (552 reviews)
The price is ₹10,004
₹11,327 total
includes taxes & fees
17 May - 18 May

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (630 reviews)
The price is ₹5,809
₹6,447 total
includes taxes & fees
1 Jun - 2 Jun

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (74 reviews)
The price is ₹10,441
₹11,822 total
includes taxes & fees
31 May - 1 Jun

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (412 reviews)
The price is ₹7,119
₹7,900 total
includes taxes & fees
3 May - 4 May

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (570 reviews)
The price is ₹5,680
₹6,745 total
includes taxes & fees
4 May - 5 May

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,000 reviews)
The price is ₹8,587
₹9,787 total
includes taxes & fees
2 Jun - 3 Jun

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (462 reviews)
The price is ₹9,966
₹11,284 total
includes taxes & fees
17 May - 18 May

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (762 reviews)
The price is ₹4,951
₹5,346 total
includes taxes & fees
10 May - 11 May

Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (482 reviews)
The price is ₹6,551
₹7,518 total
includes taxes & fees
3 May - 4 May

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (771 reviews)
The price is ₹5,719
₹6,518 total
includes taxes & fees
4 May - 5 May

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (384 reviews)
The price is ₹6,880
₹8,170 total
includes taxes & fees
24 May - 25 May

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
6.8 out of 10, (617 reviews)
The price is ₹5,980
₹6,817 total
includes taxes & fees
3 May - 4 May

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
The price is ₹6,151
₹7,010 total
includes taxes & fees
3 May - 4 May

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (62 reviews)
The price is ₹6,444
₹7,361 total
includes taxes & fees
17 May - 18 May

Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (181 reviews)
The price is ₹10,118
₹12,015 total
includes taxes & fees
10 May - 11 May

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (106 reviews)
The price is ₹52,100
₹57,819 total
includes taxes & fees
3 May - 4 May

Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51Union City
6.8 out of 10, (391 reviews)
The price is ₹5,410
₹6,425 total
includes taxes & fees
3 May - 4 May

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is ₹12,055
₹13,649 total
includes taxes & fees
28 May - 29 May

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (284 reviews)
The price is ₹7,261
₹8,058 total
includes taxes & fees
18 May - 19 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Holiday Inn Express & Suites Sikeston Southwest by IHG
8/10 Good
More cheap stays in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
The price is ₹5,719 per night from 4 May to 5 May
₹5,719
₹6,518 total
4 May - 5 May
includes taxes & fees
8.4/10 Very Good! (771 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- Advance Hotels
- B&B in Benton
- Motels in Bragg City
- Campbell Hotels
- Resorts in Cape Girardeau
- All-Inclusive Hotels in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Hotels with Breakfast in Cape Girardeau
- Motels in Cape Girardeau
- B&B in Charleston
- Cape Girardeau County Hotels
- Hotels Suites in Hayti
- Cheap Hotels in Jackson
- Hotels Suites in Jackson
- Hotels near Southeast Missouri State University









































































