A tree-lined landscape with a river and fields.

East Prairie Hotels from ₹6,299

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Check prices for these dates

Next weekend
7 Aug - 9 Aug
In two weeks
14 Aug - 16 Aug

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Our top choices for East Prairie hotels

Indoor pool, outdoor pool

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,004 reviews)
"Nice hotel with evening dinner and buffet breakfast."
United States
Sally
The price is ₹10,588
₹12,173 total
includes taxes & fees
15 Aug - 16 Aug
Drury Inn & Suites Sikeston, MO
Exterior

2. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (597 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is ₹10,671
₹12,082 total
includes taxes & fees
19 Aug - 20 Aug
Hampton Inn Sikeston
Exterior

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (488 reviews)
"Very clean room breakfast was good"
United States
michael
The price is ₹8,872
₹10,045 total
includes taxes & fees
30 Aug - 31 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free daily full breakfast

4. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,000 reviews)
"Good location. Other nearby hotels were questionable, but felt safe in Best Western."
United States
Kevin
The price is ₹9,080
₹10,349 total
includes taxes & fees
17 Aug - 18 Aug
Best Western Plus Sikeston I-55
Property amenity

5. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (101 reviews)
"Perfect last minute stop on our road trip Very clean, well maintained and pleasant staff"
United States
Dwain
The price is ₹10,493
₹11,881 total
includes taxes & fees
20 Aug - 21 Aug
Fairfield Inn & Suites by Marriott Sikeston
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

6. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (651 reviews)
"The room was spacious and could have used a small loveseat for TV watching. The breakfast didn't include pastries or a waffle machine. There's instant oatmeal and apples, OJ, coffee and apple juice. I'm hoping as they continue to renovate it will be like other hotels I've stayed at for the same price."
United States
France
The price is ₹5,676
₹6,299 total
includes taxes & fees
2 Aug - 3 Aug
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior

7. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (423 reviews)
"Definitely be back and will recommend to my family and friends"
United States
Bobby
The price is ₹6,796
₹7,542 total
includes taxes & fees
4 Aug - 5 Aug
The Riverstone Hotel Charleston-Sikeston
Desk, blackout curtains, iron/ironing board (on request), free WiFi

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (805 reviews)
"I love it there."
United States
Sharika West
The price is ₹6,293
₹7,172 total
includes taxes & fees
2 Aug - 3 Aug
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Iron/ironing board (on request), free WiFi, bed sheets

9. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (148 reviews)
"Great clean place to stay at"
United States
William
The price is ₹5,377
₹6,397 total
includes taxes & fees
3 Aug - 4 Aug
Country Yard Inn and Suite
1 bedroom, desk, laptop workspace, blackout curtains

10. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,004 reviews)
The price is ₹6,439
₹7,339 total
includes taxes & fees
1 Sept - 2 Sept
Days Inn and Suites by Wyndham Sikeston
Property amenity

11. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (19 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ₹10,398
₹11,773 total
includes taxes & fees
16 Aug - 17 Aug
TownePlace Suites by Marriott Sikeston
Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi

12. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (69 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is ₹7,899
₹9,022 total
includes taxes & fees
2 Aug - 3 Aug
Super 8 By Wyndham Marston
Exterior

13. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (302 reviews)
"Hotel was nice an clean. Friendly staff. Clean hotel rooms and free breakfast every morning."
United States
Starlette
The price is ₹8,894
₹10,137 total
includes taxes & fees
28 Aug - 29 Aug
Comfort Inn & Suites Sikeston I-55
Room, 1 King Bed, Non Smoking | View from room

14. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is ₹6,610
₹7,336 total
includes taxes & fees
2 Aug - 3 Aug
Eagle Inn Charleston
Lobby

15. Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (420 reviews)
"Clean room, excellent staff, wonderful breakfast"
United States
Ben
The price is ₹7,555
₹8,972 total
includes taxes & fees
23 Aug - 24 Aug
Sleep Inn at Discovery Park of America
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout curtains, free WiFi

16. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (658 reviews)
"Staff is great rooms clean no bugs and bed was comfortable "
United States
James
The price is ₹6,096
₹6,948 total
includes taxes & fees
9 Aug - 10 Aug
Super 8 by Wyndham Sikeston/Miner Area
Free buffet breakfast

17. Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.2 out of 10, Very good, (533 reviews)
"Breakfast was filling and fresh. Short overnight stay which completely met our needs First level room with convenient vehicle parking right outside the door which made moving luggage painless. "
United States
Lisa
The price is ₹6,000
₹7,125 total
includes taxes & fees
29 Aug - 30 Aug
Quality Inn Union City US 51
Lobby

18. Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (575 reviews)
"Very clean and nice place and people."
United States
Jade
The price is ₹5,708
₹6,779 total
includes taxes & fees
16 Aug - 17 Aug
Country Hearth Inn & Suites Union City
Lobby

19. Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (398 reviews)
"Over all a good stay however often times no one at front desk sauna not working no eggs or sausage with breakfast could atleast to boiled eggs"
United States
Richard
The price is ₹5,437
₹6,457 total
includes taxes & fees
4 Aug - 5 Aug
Hospitality House Union City I 69 / US 51
Lobby

20. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (293 reviews)
"Breakfast was sparse. This motel needs a complete overhaul. "
United States
Susan
The price is ₹6,152
₹6,827 total
includes taxes & fees
21 Aug - 22 Aug
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
A tree-lined landscape with a river and fields.

Top East Prairie Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Our room looked new and clean and specious ! Breakfast was delicious, variety and better quality compared to some other.. The air conditioner was quite as well.The environments were safe. Overall we loved our stay, thank you for your great service !"
palita 1-night trip
Posted 20 hours ago
Drury Inn & Suites Sikeston, MO

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ₹6,439 per night from 1 Sept to 2 Sept
₹6,439
₹7,339 total
1 Sept - 2 Sept
includes taxes & fees

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Best Western Plus Sikeston I-55 and Days Inn and Suites by Wyndham Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
How is it staying in East Prairie?
Visitors will definitely enjoy all that East Prairie has to offer. There are 37 hotels and other accommodation options in the surrounding area. Find out more about East Prairie.
What are the top places to visit in East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Central Park and Sikeston Depot Museum in the area. Take a look at what more there is to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.