A busy city street with tall buildings, including a prominent skyscraper in the background.

Search Luxury Hotels in Downtown Buffalo

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Downtown Buffalo Luxury Hotels

Our top choices for Downtown Buffalo luxury hotels

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

1. Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Downtown Buffalo
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    City centre luxury retreat offers hot springs, full-service spa, and designer rooms in Buffalo.
The price is ₹24,133
₹28,176 total
includes taxes & fees
16 Nov - 17 Nov
Curtiss Hotel, an Ascend Collection Hotel
A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

2. Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Downtown Buffalo
10.0 out of 10, Exceptional, (56 reviews)
  • cleanliness
    Indulge in luxury at this Buffalo bed & breakfast, where champagne service and heated floors create a harmonious city centre retreat.
The price is ₹28,761
₹33,478 total
includes taxes & fees
18 Nov - 19 Nov
Buffalo Harmony House
A bar area with a round bar, multiple seating options, and a large screen displaying content.

3. Seneca Niagara Resort & Casino

Seneca Niagara Resort & Casino
4.0 star property
Downtown Niagara Falls
8.6 out of 10, Excellent, (3,812 reviews)
The price is ₹11,039
₹13,413 total
includes taxes & fees
27 Oct - 28 Oct
Seneca Niagara Resort & Casino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown Buffalo Hotel Reviews

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

10/10 Excellent
"The room was clean. A great breakfast. Had plenty of parking."
James 1-night trip
Posted less than an hour ago
Sleep Inn & Suites Buffalo Airport

Frequently asked questions

Are you looking for a luxury hotel for your stay in Downtown Buffalo?
During your visit, you might want to enjoy the museums and entertainment which Downtown Buffalo is known for.
What's the best luxury accommodation option in Downtown Buffalo?
Curtiss Hotel, an Ascend Collection Hotel is a luxury hotel with 2 bars and a full-service spa, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Another upscale option for your trip is Buffalo Harmony House.
What's there to see and do in Downtown Buffalo?
Enjoy all that Downtown Buffalo has to offer and visit Chippewa District, Statler Tower and Shea's Performing Arts Center. If you have spare time during your trip, you might want to make a stop at Buffalo City Hall and Kleinhans Music Hall.
How can I get around Downtown Buffalo?
It's easier to get around town comfortably when you know your options. Nearby metro stations include Fountain Plaza Station, Lafayette Square Station and Church Station.

Explore a world of travel with Expedia