Compare and book 5 Star hotels in Southwest Florida, Florida
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Top Southwest Florida 5 Star Hotels

The St. Regis Longboat Key Resort
The St. Regis Longboat Key Resort

The Ritz-Carlton, Naples
The Ritz-Carlton, Naples

The Ritz-Carlton Naples, Tiburón
The Ritz-Carlton Naples, Tiburón

Sundial Beach Resort & Spa
Sundial Beach Resort & Spa

Naples Beach Club, a Four Seasons Resort
Naples Beach Club, a Four Seasons Resort

Marco Beach Ocean Resort
Marco Beach Ocean Resort
Explore similar 4-star hotels

Sunseeker Resort Charlotte Harbor
Learn more about Southwest Florida
Amazing beaches, golf courses and popular sights from Siesta Key Beach to Lido Beach—explore Southwest Florida, a destination also known for its island views.

Find out more about Southwest Florida
Find out more about Southwest Florida
Stay in Luxury: 5 Star Hotels in Southwest Florida
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Southwest Florida trip. You'll join the multitudes of holidaymakers who have made Southwest Florida so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Southwest Florida and indulge in the finer things in life for a while.
5-Star Hotels in Southwest Florida
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Southwest Florida are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and Southwest Florida 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Southwest Florida! Choose one of our Southwest Florida 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
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Southwest Florida Hotel Reviews
Southwest Florida Hotel Reviews

The St. Regis Longboat Key Resort
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in Southwest Florida by Star Rating
Accommodation near Southwest Florida attractions
- Hotels near Siesta Key Beach
- Hotels near Lido Beach
- Hotels near Venice Beach
- Hotels near IMG Academy
- Hotels near Key West Express
- Hotels near St. Armands Circle
- Hotels near Mall at University Town Center
- Hotels near Turtle Beach
- Hotels near Naples Beach
- Hotels near Anna Maria Beach
- Hotels near Fort De Soto Park
- Hotels near Coquina Beach
- Hotels near Barefoot Beach
- Hotels near Fifth Avenue South
- Hotels near Naples Pier
- Hotels near Caspersen Beach
Choose Your Southwest Florida Hotel Style
- Beach Resorts & Hotels in Southwest Florida
- Business Hotels in Southwest Florida
- Cheap Hotels in Southwest Florida
- Family-Friendly Hotels in Southwest Florida
- Golf Hotels in Southwest Florida
- Historic Hotels in Southwest Florida
- Hotels Suites in Southwest Florida
- Hotels near Museums in Southwest Florida
- Hotels with Air Conditioning in Southwest Florida
- Hotels with Balcony in Southwest Florida
- Hotels with Breakfast in Southwest Florida
- Hotels with Connecting Rooms in Southwest Florida
- Hotels with Entertainment in Southwest Florida
- Hotels with Gym in Southwest Florida
- Hotels with Hot Tubs in Southwest Florida
- Hotels with Laundry Service in Southwest Florida
- Hotels with Parking in Southwest Florida
- Hotels with Parking in Southwest Florida
- Hotels with Restaurant in Southwest Florida
- Hotels with Swimming Pool in Southwest Florida
- Hotels with Views in Southwest Florida
- Hotels with Wifi in Southwest Florida
- Hotels with a Bar in Southwest Florida
- Hotels with smoking rooms in Southwest Florida
- Luxury Hotels in Southwest Florida
- Marina Hotels in Southwest Florida
- Pet-Friendly Hotels in Southwest Florida
- Romantic Hotels in Southwest Florida
- Shopping Hotels in Southwest Florida
- Spa Hotels in Southwest Florida
- Sports Hotels in Southwest Florida
- Wedding Hotels in Southwest Florida
More accommodation types in Southwest Florida
- Motels in Southwest Florida
- Resorts in Southwest Florida
- Aparthotels in Southwest Florida
- Condo Rentals in Southwest Florida
- Condo Resorts in Southwest Florida
- Houseboats in Southwest Florida
- Apartments in Southwest Florida
- Holiday Homes in Southwest Florida
- Villas in Southwest Florida
- B&B in Southwest Florida
- Cottages in Southwest Florida
- Guest Houses in Southwest Florida
- Inns in Southwest Florida
Explore more hotels
- The St. Regis Longboat Key Resort
- Margaritaville Beach Resort Fort Myers
- Hilton Naples
- Holiday Inn Express Cape Coral-Fort Myers Area by IHG
- The Lighthouse Resort Inn & Suites
- Siesta Key Beach Resort and Suites
- Anna Maria Beach Resort
- Zota Beach Resort
- Extended Stay America Premier Suites - Bradenton
- Tropical Breeze Resort
- JW Marriott Marco Island Beach Resort
- Hyatt Regency Coconut Point Resort & Spa
- Marco Beach Ocean Suites
- Trianon Bonita Bay
- Ramada by Wyndham Venice Hotel Venezia
- Embassy Suites by Hilton Fort Myers Estero
- Pelican Post at Anna Maria Island Inn
- Dolphin Key Resort
- The Resort at Longboat Key Club
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