Compare and book 5 Star hotels in Key West, Florida

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Top Key West 5 Star Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What are the best 5-star hotels in Key West?
Treat yourself to a luxurious stay at Casa Marina Key West, Curio Collection by Hilton. This is one of the top 5-star hotels in Key West based on Expedia customer reviews. From its plush guest rooms to its premium amenities and services, you can expect an exceptional guest experience.
How much does it cost to stay in a 5-star hotel in Key West?
How much you pay for a 5-star hotel in Key West depends on factors like when you plan to go and the length of your escape. An insider tip for scoring an awesome deal? Use our pricing filters to compare the available hotels for your preferred dates.

  • Search for the lowest price per night from ₹10,436

What makes a hotel 5 stars in Key West?
From high-end restaurants and all-day gyms to pools and deluxe bedding, the 5-star experience in Key West is all about comfort and luxury. But it requires more than just top-notch perks to receive a 5-star rating. Accommodation must also deliver superb guest-focused services like in-room beauty treatments, laundry and dry cleaning and 24/7 room service.