Compare and book 4 Star hotels in Southern Indiana, United States of America
Change your mind
Be picky
Check availability on Southern Indiana 4 Star Hotels
Top Southern Indiana 4 Star Hotels

Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Embassy Suites Louisville Downtown

The Brown Hotel

Hotel Genevieve part of JdV by Hyatt

Hyatt Regency Louisville

21c Museum Hotel Louisville

The Grady
Learn more about Southern Indiana
Explore plenty to see and do in Southern Indiana—live music, sports teams and popular sights like Ohio River Valley.

Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville
Find out more about Southern Indiana
Take Your Pick of 4 Star Hotels in Southern Indiana
The get-go of any holiday starts with choosing a great spot. Southern Indiana has been a popular destination with guests because it offers so much to do and see. But, "location, location, location" applies to more than just what city where your plane lands. Now that you have a feel for the town, it's time you to get to know your new digs.
Accommodations as Picturesque as Southern Indiana
Search Expedia.com.sg for the right 4 Star Southern Indiana Hotel to suit your fancy. Plenty of these people wrote tips to help you select the accommodation that is the right fit for your holiday.You'll be more than glad to get back to your resort every night. Southern Indiana has dozens of good options in the 4-star hotel range that create the ideal getaway.
A stay at one of these lodgings ensure that whether you are just relaxing after a day of checking out Southern Indiana or you are ready to lie down for the night, you'll be as comfortable as possible. You won't go without a thing during your stay at one of these accommodations. Visitors have consistently given them high marks for their attentive service. It's no surprise that loads of guests recommend it.
Reserve a 4-Star Hotel in Southern Indiana Today!
Your trip to Southern Indiana should be one that you'll reminisce over for years to come, and booking a 4-star hotel will help create memories that are incredible. Make sure to make a reservation soon. With so few hotels, and plenty of people desiring to vacation in Southern Indiana, you may miss out on your perfect hotel.
Frequently asked questions
Explore a world of travel with Expedia
Hotels in Southern Indiana by Star Rating
Accommodation near Southern Indiana attractions
- Hotels near KFC Yum Center
- Hotels near Kentucky International Convention Center
- Hotels near Holiday World and Splashin' Safari
- Hotels near Louisville Slugger Museum
- Hotels near Bally's Evansville Casino
- Hotels near Fourth Street Live!
- Hotels near Ford Center
- Hotels near Belterra Casino
- Hotels near Clifty Falls State Park
- Hotels near University of Southern Indiana
- Hotels near French Lick Casino
- Hotels near Kentucky Bourbon Trail Visitor Center
- Hotels near 21c Museum Hotel
- Hotels near Horseshoe Southern Indiana Casino
- Hotels near Big Splash Adventure
- Hotels near Spring Mill State Park
- Hotels near University of Evansville
- Hotels near Belle of Louisville
Choose Your Southern Indiana Hotel Style
- Business Hotels in Southern Indiana
- Casino Hotels in Southern Indiana
- Cheap Hotels in Southern Indiana
- Family-Friendly Hotels in Southern Indiana
- Golf Hotels in Southern Indiana
- Historic Hotels in Southern Indiana
- Hotels near Museums in Southern Indiana
- Hotels with Air Conditioning in Southern Indiana
- Hotels with Airport Transfers in Southern Indiana
- Hotels with Breakfast in Southern Indiana
- Hotels with Connecting Rooms in Southern Indiana
- Hotels with Entertainment in Southern Indiana
- Hotels with Gym in Southern Indiana
- Hotels with Hot Tubs in Southern Indiana
- Hotels with Indoor Pools in Southern Indiana
- Hotels with Laundry Service in Southern Indiana
- Hotels with Parking in Southern Indiana
- Hotels with Parking in Southern Indiana
- Hotels with Restaurant in Southern Indiana
- Hotels with Room Service in Southern Indiana
- Hotels with Swimming Pool in Southern Indiana
- Hotels with Views in Southern Indiana
- Hotels with Wifi in Southern Indiana
- Hotels with a Bar in Southern Indiana
- Hotels with smoking rooms in Southern Indiana
- Luxury Hotels in Southern Indiana
- Pet-Friendly Hotels in Southern Indiana
- Romantic Hotels in Southern Indiana
- Shopping Hotels in Southern Indiana
- Spa Hotels in Southern Indiana
- Sports Hotels in Southern Indiana
- Wedding Hotels in Southern Indiana
More accommodation types in Southern Indiana
- Cottages in Southern Indiana
- Motels in Southern Indiana
- Apartments in Southern Indiana
- Aparthotels in Southern Indiana
- B&B in Southern Indiana
- Holiday Homes in Southern Indiana
- Resorts in Southern Indiana
- Condo Rentals in Southern Indiana
- Guest Houses in Southern Indiana
- Hostels in Southern Indiana
- Inns in Southern Indiana
Explore more hotels
- Motel 6 Jeffersonville, In - Louisville
- Baymont by Wyndham Dale
- Garner Hotel Evansville East by IHG
- Hampton Inn Evansville
- Comfort Inn & Suites Evansville Airport
- Ramada by Wyndham Sellersburg/Louisville North
- Clarion Inn & Suites
- DoubleTree by Hilton Evansville
- Santas Lodge and Resort
- Hampton Inn Louisville-North/Clarksville
- Holiday Inn Express & Suites Evansville North by IHG
- Spark by Hilton Evansville East, IN
- The Villas at French Lick Springs
- Red Roof Inn Charlestown
- Holiday Inn Express New Albany - Louisville NW by IHG
- Baymont by Wyndham Corydon
- Travelodge by Wyndham Sellersburg / Louisville North
- Hometowne Inn & Suites
- New Harmony Inn Resort and Conference Center
More ways to book
Expedia's Latest Trends
- Hotels in Atlanta
- Hotels in New Haven
- Hotels in Seattle
- Cheap Hotels in Chicago
- Hotels in Philadelphia
- Hotels in Santa Clara
- Hotels in Berkeley Heights
- Hotels in San Francisco
- Hotels in New York
- Cheap Hotels in New York
- Hotels with Early Check-in in New York
- Hotels in Erie
- Hotels in Ames
- Hotels in West Lafayette
- Hotels in Newark
- Hotels near Mars Desert Research Center
- Hotels in Las Vegas
- Hotels in Los Angeles
- Hotels in Salt Lake City
- Hotels in Miami
- Hotels in Chicago
- Hotels in San Jose
- Hotels in Ann Arbor