Top Romantic Southeast Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway, Winona, MN

2 hours drive from Mayo Clinic

Stay at this 3.5-star B&B in Winona. Enjoy free breakfast, free parking and a business centre. Popular attractions Watkins Heritage Museum and Polish Cultural ...

10/10 Exceptional! (361 reviews)

The Inkeeper Richard was gracious, welcoming and informative about the area. The property is beautiful and historic. Food and service were perfect. I highly recommend this B & B for anyone visiting the Winona area.

Reviewed on 21 Oct 2025

St James Hotel, a Historic Hotel of America

406 Main St., Red Wing, MN

2 hours drive from Mayo Clinic

Stay at this 3.5-star spa hotel in Red Wing. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...

9.2/10 Wonderful! (1,021 reviews)

Couples like: full-service spa, bar

Travellers say...

Surprised how clean and nice room was for its age. No complaints!

Reviewed on 27 Oct 2025

AmericInn by Wyndham Austin

1700 8th St NW, Austin, MN

2 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Austin. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...

8.6/10 Excellent! (707 reviews)

Highly Reccomend

Love the room. Just what was needed after working all day and then driving 4 hours. We choice the king studio and the whirlpool tub was heaven.

Reviewed on 18 Oct 2025

See all 926 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.