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Top Romantic Upstate South Carolina Hotels

Greenville Marriott

One Parkway E Greenville SC

2 hours drive from Clemson University

Stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff ...

8.6/10 Excellent! (684 reviews)

"Property was tucked away and quiet. Staff at check in and check out was very cheerful and helpful."

Reviewed on 3 Aug 2026

Hotel Domestique

10 Road of Vines Travelers Rest SC

2 hours drive from Clemson University

Stay at this boutique hotel in Travelers Rest. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Mountain Park Golf and Les Mullinax Park ...

See all 3,061 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.