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Top Pet-friendly Southern Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

4353 Canal Pl SE Rochester MN

11 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

7.6/10 Good! (1,059 reviews)

"We loved the room and hot tub. The breakfast had nice options. The rooms were comfortable. It had soft mattresses."

Reviewed on 6 Nov 2026

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

7.8/10 Good! (1,054 reviews)

"There were children of one of the employees, who I think was living there, running up and down the hall constantly. You could hear them fighting with one another. It made it hard for my ill wife to rest"

Reviewed on 7 Nov 2026

Spark by Hilton Rochester South

4165 Maine Ave SE Rochester MN

10 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

See all 1,252 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.