Southern Minnesota Trip

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Where to stay in Southern Minnesota

Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
An aerial view of a cityscape with various buildings, including a prominent clock tower and several high-rise structures.

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

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A calm river reflecting a bridge and buildings, surrounded by trees and a clear sky.

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Mayo Civic Center and Cascade Lake Beach.

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A sunset over a city skyline reflected in a calm lake, with industrial buildings and trees in the foreground.

Historic Southwest

While visiting Historic Southwest, you might make a stop by sights like Soldiers Field Veterans Memorial and Plummer House.

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A cafe interior with a wooden clock, hanging lights, and a counter with various items.

Historic Downtown Winona

You'll enjoy the live music and spas in Historic Downtown Winona. You might want to make time for a stop at Mississippi River or Winona County Historical Society.

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East Side Pioneers

If you're spending some time in East Side Pioneers, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

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Top hotels in Southern Minnesota

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
₹6,876
₹7,917 total
13 Oct - 14 Oct
includes taxes & fees
Med City Inn & Suites - Mayo Clinic Area
Kahler Grand Hotel

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
₹13,645
₹15,709 total
8 Oct - 9 Oct
includes taxes & fees
Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
₹7,037
₹8,101 total
25 Oct - 26 Oct
includes taxes & fees
8.2/10 Very good! (1,524 reviews)
"Good location for access to restuarants, clinic, St. Mary's. Nice room and helpful staff."

Reviewed on 7 Oct 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
See all 1,230 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Minnesota attractions

Forestville Mystery Cave State Park

9.0/10 (22 reviews)
Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.
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Mayo Civic Center

9.2/10 (818 reviews)
Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.
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Mayo Clinic Health System Event Center

8.8/10 (246 reviews)
Catch an event at Mayo Clinic Health System Event Center during your trip to Mankato. Discover the cafes and its entertainment venues while you're in the area.
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Apache Mall

8.6/10 (1,101 reviews)
During your visit to Rochester, you can find the perfect gifts to bring home at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Rochester Recreation Center

8.0/10 (205 reviews)
Catch an event at Rochester Recreation Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Laura Ingalls Wilder Museum

9.0/10 (33 reviews)
You can spend time studying the exhibits at Laura Ingalls Wilder Museum in Walnut Grove. Take in the museums while you're in the area.
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National Volleyball Center

7.8/10 (151 reviews)
Catch an event at National Volleyball Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Welch Village Ski Area

8.6/10 (16 reviews)
Hit the slopes in Welch with a visit to Welch Village Ski Area. Stroll along the area's riverfront or simply enjoy its cafes.
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Frequently asked questions

How much does a Southern Minnesota holiday package cost?
Live it up in Southern Minnesota from as low as . We offer a great selection of rental cars, hotels and flights to suit every style and budget. You can pick up even better deals when you add some activities or tours to your holiday package.
How do I get a cheap travel package to Southern Minnesota?
Imagine all the amazing things you could do in Southern Minnesota with extra cash in your wallet. Watch your savings stack up when you bundle your flights, hotels and other bookings into a Southern Minnesota holiday package. You have loads of choice when you book with Expedia too. In fact, you can select from more than 550 airlines and 1,000,000 hotel options worldwide. Whether you're taking off with the entire family or travelling on your own, planning a getaway to Southern Minnesota is better with a package.
What are the top hotels in Southern Minnesota?
For properties in Rochester with cosy beds and friendly service, look up Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you're stopping by Lake City as well, you can look forward to a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southern Minnesota holiday?
It can be hard to know when the best time is to book your holiday to Southern Minnesota. But typically the earlier you book, the more affordable the prices. In some cases, you can secure your flights and hotels up to a year before your departure date. If you're thinking of a last-minute getaway, no need to fret! There are great bargains popping up on Expedia all the time.
What does an Expedia Southern Minnesota travel package include?
Much of that depends on you. You can choose from a variety of Southern Minnesota bundles, such as a rental car, flight and hotel. You can also book a flight with a hotel, or a flight with a rental car. Once you've made your booking, you can add the fun stuff like activities and tours. Whatever your dream Southern Minnesota break looks like, you're sure to save!
What should I know before booking a Southern Minnesota travel package?
Bundling your bookings into a Southern Minnesota holiday package is the most convenient way to organise your trip. Not only that, you'll get great discounts when you combine your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a Southern Minnesota Expedia holiday package?
Yes, you sure can. We offer more than 550 airline partners all over the world, so fly with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Southern Minnesota holiday package?
We totally get it — life sometimes gets in the way of your plans. If you've booked a Southern Minnesota holiday package and have to cancel or change it, we can help. We suggest browsing our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to cancel or amend your itinerary at no cost. If it's been longer than 24 hours, your airline, hotel or car rental company may impose a fee.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.