Southern Minnesota Trip

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Where to stay in Southern Minnesota

Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Find hotels in Downtown Rochester

Top hotels in Southern Minnesota

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
The price is ₹12,095 per night from 8 Jan to 9 Jan
₹12,095
₹13,925 total
8 Jan - 9 Jan
includes taxes & fees
8.2/10 Very Good! (1,848 reviews)
Clean, comfortable room. The staff was very helpful

Reviewed on 2 Jan 2026

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
The price is ₹11,647 per night from 11 Jan to 12 Jan
₹11,647
₹13,409 total
11 Jan - 12 Jan
includes taxes & fees
7.8/10 Good! (1,527 reviews)
Clean big room close to the Mayo

Reviewed on 31 Dec 2025

Kahler Inn and Suites - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
The price is ₹7,223 per night from 24 Jan to 25 Jan
₹7,223
₹8,315 total
24 Jan - 25 Jan
includes taxes & fees
8.8/10 Excellent! (895 reviews)
The hotel was clean and a friendly staff at check in. We love that the hotel skyway is connected to Mayo, so could walk to appts. inside on a cold day. We also appreciated a noon check out.

Reviewed on 1 Jan 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
See all 1,195 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Mayo Clinic Hospital - Saint Marys Campus

If Mayo Clinic Hospital - Saint Marys Campus is what brings you to town, hopefully you'll have a chance to explore more of Rochester.

Mayo Clinic Hospital - Saint Marys Campus

Apache Mall

During your visit to Rochester, you can find the perfect gifts to bring home at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

Apache Mall

Minnesota State University

Enjoy the student vibe when you visit Minnesota State University during your trip to Mankato. Attend a sporting event while you're in the area or simply enjoy its cafes.

Minnesota State University

Frequently asked questions

Can I cancel my flight booking to Southern Minnesota due to COVID-19?
Many airlines now provide more flexibility due to COVID-19. Our handy Customer Service Portal will help find an answer to most queries about flight changes or cancellations. It's also worth reading through the terms and conditions of your airfare — preferably before you make a booking!
What's the best way to find cheap flights to Southern Minnesota that have flexible change policies?
We understand that travel arrangements can change in a flash, so choosing a flexible airfare with Expedia is always a clever idea. Simply check the "No change fee" box directly under the "Flexible change policies" filter. Your affordable, flexible flight to Southern Minnesota is just a few clicks away.
What are some of the general tips for travellers to Southern Minnesota during the COVID-19 outbreak?
With the ongoing impacts of the COVID-19 outbreak, travelling today comes with a few extra challenges. Make a note of the following tips before jumping on your flight to Southern Minnesota:
  • Before committing to anything, see if any travel bans or restrictions apply — in both your origin and destination. Get the latest updates by checking government and airport websites.
  • You're required to wear a face mask at the airport, including at security checkpoints. Be prepared to lower your mask for ID purposes when asked.
  • Rather than handing a TSA employee your boarding pass, place it straight on the reader yourself. Once that's done, hold it up for inspection.
  • One liquid hand sanitizer container is now allowed in your carry-on luggage. It must be no larger than 12 oz (350 ml), and you'll have to remove it from your bag for X-ray scanning.
  • Place any personal items (phone, keys and wallet) in your carry-on instead of a bin to reduce handling during screening.
  • If you're taking food through the security checkpoint, place it in a clear plastic bag and then into a screening bin. This lessens the likelihood that a TSA agent will need to touch your food container or carry-on bag for inspection.

Which airlines fly to Southern Minnesota?
Delta operates flights into or near Southern Minnesota, including 10082 that land at Minneapolis - St. Paul Intl. Airport (MSP) each month. Choose your travel dates and then lock in your ticket early for an awesome deal.
How can I find cheap tickets to Southern Minnesota?
Book well in advance, consider nearby airports, use frequent flyer miles — you're not short of ways! Another one is to make the most of Expedia's "flexible dates" feature. Find your Southern Minnesota flight, then compare the cheapest prices for nearby dates. In the last seven days, the best price for a flight to Southern Minnesota was .
How much is a flight to Southern Minnesota?
In the last seven days, return airfares to Southern Minnesota sold for as little as and reached a maximum of . For one-way fares taking off from (), the lowest amount paid during this same period was only .
What are the most popular airports to fly into in Southern Minnesota?
Pack your suitcase and fly into Minneapolis - St. Paul Intl. Airport (MSP), Southern Minnesota's main flight hub. Book one of the 13006 flights that land at this awesome destination every month.
When is the cheapest time to fly to Southern Minnesota?
Fly out on a Tuesday to boost your chances of securing the cheapest flight to Southern Minnesota. Mondays are usually the second most affordable day to take off. Saturday is typically the priciest day to fly anywhere.
How much is a plane ticket to Southern Minnesota?
Prices varied from to over the last seven days. When you're ready to book, we're ready to help you secure a low-cost flight to Southern Minnesota.
Which airlines with flights to Southern Minnesota employ COVID-19 cleanliness policies?
In response to the ongoing pandemic, most airlines have implemented new precautionary measures to help everybody fly with extra peace of mind. Here are some great examples:
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • Sun Country Airlines - this airline is known for electrostatic cleaning and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.