Southeast Minnesota Luxury Holidays 2026

Photo by Sara Crotts

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Top Luxury Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (2,338 reviews)

"Perfect for the outpatient setting for Mayo. Definitely recommend using valet for just a little more it’s worth it and so easy!"

Reviewed on 1 Oct 2026

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

7.8/10 Good! (1,026 reviews)

"A terrible place- We arrived in the evening. The guy that checked us in didn't seem friendly. We went out and ate supper after check in. When we got back, it was late. We should have checked the room better before we left to eat. The ceiling in the bathroom had a big bulge, and the bathrm exhaust ..."

Reviewed on 30 Sept 2026

AmericInn by Wyndham Northfield

1320 Bollenbacher Dr Northfield MN

2 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Northfield. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

See all 951 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.