Southeast Minnesota Luxury Holidays 2026

Photo by Sara Crotts

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Top Luxury Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (2,263 reviews)

"The location could not be better."

Reviewed on 15 Aug 2026

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

8/10 Very good! (1,005 reviews)

"We had an issue with our first room battery was dead on door lock so they were able to move us. We appreciated the accomadati9n and the breakfast. Staff was helpful. Could use maybe a swing or slide outside by the dinosaur statue. My son pived it."

Reviewed on 15 Aug 2026

AmericInn by Wyndham Northfield

1320 Bollenbacher Dr Northfield MN

2 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Northfield. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

8.2/10 Very good! (683 reviews)

"Friendly staff, easy check and breakfast was simple but fine. Hallway carpet should be changed, maybe figure out a way to reduce dampness in the air in the room. Room itself was clean."

Reviewed on 13 Aug 2026

See all 924 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.