Southern Minnesota Luxury Holidays

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to ₹43,962 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury Southern Minnesota Hotels

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,460 reviews)
"Checking in is great rooms new a lot of updating!"

Reviewed on 19 Jul 2025

Kahler Grand Hotel
AmericInn by Wyndham Blue Earth

AmericInn by Wyndham Blue Earth

2 out of 5
1495 Domes Dr, Blue Earth, MN
  • 5 hours drive from Mayo Clinic
Stay at this business-friendly hotel in Blue Earth. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the property condition in their reviews. ...
7.8/10 Good! (437 reviews)
"Very clean and spacious"

Reviewed on 5 Jul 2025

AmericInn by Wyndham Blue Earth
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
Stay at this family-friendly motel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
7.8/10 Good! (1,005 reviews)
"Staff was very helpful and nice. Room was clean but old. Nice pool. I would stay there again. Has a Famous Dave's attached to it. Nice little honey hole in Rochester."

Reviewed on 17 Jul 2025

Med City Inn & Suites - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.