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Top Luxury Southern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the restaurant and the helpful staff ...

9.4/10 Exceptional! (1,004 reviews)

"Museum is very nice"

Reviewed on 25 Jun 2026

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

1 hour drive from Holiday World and Splashin' Safari

Stay at this luxury resort in West Baden Springs. Enjoy free Wi-Fi, a full-service spa and 15 restaurants. Popular attractions French Lick Winery and FLWB Indoor ...

The Brown Hotel

335 W Broadway Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,254 reviews)

"Went for a six day trip and we loved the charm of the hotel. Bar drinks were great and room was cleaned each day, which was nice."

Reviewed on 26 Jun 2026

See all 1,555 properties in Southern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.