Southern Indiana Luxury Holidays 2026

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Top Luxury Southern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the restaurant and the helpful staff ...

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

1 hour drive from Holiday World and Splashin' Safari

Stay at this luxury resort in West Baden Springs. Enjoy free Wi-Fi, a full-service spa and 15 restaurants. Popular attractions French Lick Winery and FLWB Indoor ...

The Brown Hotel

335 W Broadway Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,288 reviews)

"Best hotel mattress EVER. Slept like a rock."

Reviewed on 10 Aug 2026

See all 1,633 properties in Southern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.