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Top Luxury Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the breakfast and the pool in their ...

7.4/10 Good! (1,000 reviews)

"Clean"

Reviewed on 14 Jul 2025

Spark by Hilton Amarillo East

2301 East I40, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

8.4/10 Very Good! (49 reviews)

"Easy check in and quiet! Very clean! Pet friendly and area to walk dogs!"

Reviewed on 17 Jul 2025

Hawthorn Suites by Wyndham Lubbock

4435 Marsha Sharp Fwy, Lubbock, TX

25 min walk from Texas Tech University

Stay at this 3-star business-friendly hotel in Lubbock. Enjoy free Wi-Fi, free parking and a fitness centre. Our guests praise the helpful staff and the clean ...

7.8/10 Good! (1,000 reviews)

"Clean nice hotel. We enjoyed our stay I just don’t understand why the “pet room” would be on the fourth floor. Had to take dogs up four flights of stairs. But it was also the nicest room, that accommodated pets, that I have ever stayed in."

Reviewed on 15 Jul 2025

See all 2,051 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.