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Top Luxury Central Missouri Hotels

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.6/10 Good! (1,005 reviews)

"never again!"

Reviewed on 19 Jun 2026

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

2 hours drive from Lake of the Ozarks

Stay at this business-friendly hotel in Columbia. Enjoy free Wi-Fi, 3 restaurants and 3 bars/lounges. Our guests praise the helpful staff and the property condition ...

9/10 Wonderful! (1,002 reviews)

"This is a nice hotel, walkable to campus. However, they tried to ignore my Expedia rate and book me in at a considerably higher rate. What was worse, I had prepaid an Expedia deposit which they had no record of. I was able to show them my email as proof. They had no interest in solving this issue ..."

Reviewed on 13 Jun 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

20 min drive from Lake of the Ozarks

Stay at this beach resort in Lake Ozark. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their ...

7.4/10 Good! (1,175 reviews)

"The pools and views were great! Would suggest adding some umbrellas to pool area- there was little to no shade. Staff was great, check-in was seamless, and all the servers were awesome! Property is definitely in need of major TLC, but otherwise stay was fine."

Reviewed on 20 Jun 2026

See all 5,130 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.