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Top Luxury Central Missouri Hotels

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

24 min walk from University of Missouri

Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.4/10 Good! (1,000 reviews)

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Reviewed on 30 Nov 2025

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

8 min walk from University of Missouri

Stay at this business-friendly hotel in Columbia. Enjoy free Wi-Fi, 3 restaurants and 3 bars/lounges. Our guests praise the helpful staff and the property condition ...

8.8/10 Excellent! (1,000 reviews)

This is the first time we have stayed at this facility and I was impressed! Location is excellent

Reviewed on 24 Nov 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

2 hours drive from University of Missouri

Stay at this beach resort in Lake Ozark. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the pool and the helpful staff in their ...

7.2/10 Good! (1,076 reviews)

Nice clean room and staff was excellent. Some taller toilets or grab bars for us older people with knee problems would be a nice touch. This resort has been a staple in the community and is very well maintained. Would definitely stay here again.

Reviewed on 5 Dec 2025

See all 4,773 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.