
Southeast Missouri Luxury Holidays
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to ₹43,962 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Luxury Southeast Missouri Hotels

Super 8 by Wyndham Pevely
1711 Highway Z, Pevely, MO
Stay at this business-friendly motel in Pevely. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Pevely Park and Sun Valley Park are located ...
5.6/10 (824 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."
Reviewed on 17 May 2025

Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Stay at this motel in Poplar Bluff. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their ...
7.8/10 Good! (1,005 reviews)
"Good"
Reviewed on 16 Jul 2025

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (1,002 reviews)
Keep up the renovations
"This hotel looked like an old apartment building renovation into a hotel with much wrk in progress. Decent stay. Spacious. Very minimal breakfast offerings. The geese outside sure left messes everywhere but the greeting cat was a nice touch"
Reviewed on 28 Jun 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.