Greenville - Spartanburg Luxury Holidays 2026

Photo by Visit Greenville, South Carolina

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Top Luxury Greenville - Spartanburg Hotels

The Westin Poinsett Greenville

120 South Main St Greenville SC

13 min walk from Bon Secours Wellness Arena

Stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle and 24-hour room service. Our guests praise the helpful ...

Hyatt Regency Greenville

220 N Main St Greenville SC

10 min walk from Bon Secours Wellness Arena

Stay at this business-friendly hotel in Greenville. Enjoy free Wi-Fi, an outdoor pool and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...

Sleep Inn at Greenville Convention Cente

231 N Pleasantburg Dr Greenville SC

5 min drive from Bon Secours Wellness Arena

Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...

8/10 Very good! (1,000 reviews)

"Super nice and affordable! I run back and forth to the hospital, was easy to get to without fighting a lot of traffic. Room was fantastic! The free coffee/tea 24 hours was a blessing! I felt safe as you are anywhere now’s days. Will rebook"

Reviewed on 30 Sept 2026

See all 1,723 properties in Greenville - Spartanburg

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.